MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Robin V et al. | Antipoliovirus flavonoids from Psiadia dentata. | 2001 | Antivir. Chem. Chemother. | pmid:11900347 |
Lopez Pila JM et al. | Lack of evidence for strand-specific inhibition of poliovirus RNA synthesis by 3-methylquercetin. | 1989 | Antiviral Res. | pmid:2540709 |
Vrijsen R et al. | The poliovirus-induced shut-off of cellular protein synthesis persists in the presence of 3-methylquercetin, a flavonoid which blocks viral protein and RNA synthesis. | 1987 | Antiviral Res. | pmid:3026245 |
Rombaut B et al. | Comparison of arildone and 3-methylquercetin as stabilizers of poliovirus. | 1985 | Antiviral Res. | pmid:3002268 |
Khouri HE et al. | Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. III. Purification and kinetic analysis of S-adenosyl-L-methionine:3-methylquercetin 7-O-methyltransferase. | 1988 | Arch. Biochem. Biophys. | pmid:3415239 |
Murota K et al. | Efficiency of absorption and metabolic conversion of quercetin and its glucosides in human intestinal cell line Caco-2. | 2000 | Arch. Biochem. Biophys. | pmid:11368329 |
Lu HW et al. | Effect of three flavonoids, 5,7,3',4'-tetrahydroxy-3-methoxy flavone, luteolin, and quercetin, on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophil. | 2001 | Arch. Biochem. Biophys. | pmid:11516163 |
Steffen Y et al. | Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. | 2008 | Arch. Biochem. Biophys. | pmid:17996190 |
Justino GC et al. | Plasma quercetin metabolites: structure-antioxidant activity relationships. | 2004 | Arch. Biochem. Biophys. | pmid:15519302 |
Boers F et al. | An improved synthesis of the anti-picornavirus flavone 3-O-methylquercetin. | 1997 | Arch. Pharm. (Weinheim) | pmid:9396391 |