MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Olennikov DN et al. | Isorhamnetin and Quercetin Derivatives as Anti-Acetylcholinesterase Principles of Marigold (Calendula officinalis) Flowers and Preparations. | 2017 | Int J Mol Sci | pmid:28767066 |
Qiu L et al. | Protective effects of isorhamnetin on N2a cell against endoplasmic reticulum stress-induced injury is mediated by PKCε. | 2017 | Biomed. Pharmacother. | pmid:28715866 |
Gao L et al. | Isorhamnetin protects against cardiac hypertrophy through blocking PI3K-AKT pathway. | 2017 | Mol. Cell. Biochem. | pmid:28176246 |
Guo R et al. | Comparative assessment of phytochemical profiles, antioxidant and antiproliferative activities of Sea buckthorn (Hippophaë rhamnoides L.) berries. | 2017 | Food Chem | pmid:27979305 |
Neveux S et al. | Natural Compounds as Occult Ototoxins? Ginkgo biloba Flavonoids Moderately Damage Lateral Line Hair Cells. | 2017 | J. Assoc. Res. Otolaryngol. | pmid:27896487 |
Tian Y et al. | Phenolic compounds extracted by acidic aqueous ethanol from berries and leaves of different berry plants. | 2017 | Food Chem | pmid:27855899 |
Mudrić SŽ et al. | The polyphenolics and carbohydrates as indicators of botanical and geographical origin of Serbian autochthonous clones of red spice paprika. | 2017 | Food Chem | pmid:27664689 |
Ferreres F et al. | HPLC-DAD-ESI/MS(n) profiling of phenolic compounds from Lathyrus cicera L. seeds. | 2017 | Food Chem | pmid:27507525 |
Seo S et al. | Isorhamnetin Inhibits Reactive Oxygen Species-Dependent Hypoxia Inducible Factor (HIF)-1α Accumulation. | 2016 | Biol. Pharm. Bull. | pmid:27803454 |
Ford CT et al. | Identification of (poly)phenol treatments that modulate the release of pro-inflammatory cytokines by human lymphocytes. | 2016 | Br. J. Nutr. | pmid:26984113 |
Liu JL et al. | Optimization of Microwave-Assisted Extraction Conditions for Five Major Bioactive Compounds from Flos Sophorae Immaturus (Cultivars of Sophora japonica L.) Using Response Surface Methodology. | 2016 | Molecules | pmid:26950107 |
Chen JH et al. | Estrogenic effects of flavonoid components in Xiaoyao powder. | 2016 | Genet. Mol. Res. | pmid:26909969 |
Jnawali HN et al. | Antituberculosis Activity of a Naturally Occurring Flavonoid, Isorhamnetin. | 2016 | J. Nat. Prod. | pmid:26974691 |
Huang L et al. | Protective Effects of Isorhamnetin on Cardiomyocytes Against Anoxia/Reoxygenation-induced Injury Is Mediated by SIRT1. | 2016 | J. Cardiovasc. Pharmacol. | pmid:26859194 |
Choi YH | The cytoprotective effect of isorhamnetin against oxidative stress is mediated by the upregulation of the Nrf2-dependent HO-1 expression in C2C12 myoblasts through scavenging reactive oxygen species and ERK inactivation. | 2016 | Gen. Physiol. Biophys. | pmid:26830132 |
Brock MT et al. | Genetic architecture, biochemical underpinnings and ecological impact of floral UV patterning. | 2016 | Mol. Ecol. | pmid:26800256 |
Yang Y and Li D | Investigation on the interaction between isorhamnetin and bovine liver catalase by spectroscopic techniques under different pH conditions. | 2016 | Luminescence | pmid:26748824 |
Juániz I et al. | Influence of heat treatment on antioxidant capacity and (poly)phenolic compounds of selected vegetables. | 2016 | Food Chem | pmid:26616976 |
Chi G et al. | Isorhamnetin protects mice from lipopolysaccharide-induced acute lung injury via the inhibition of inflammatory responses. | 2016 | Inflamm. Res. | pmid:26525359 |
Yang B et al. | Protective Effect of Isorhamnetin on Lipopolysaccharide-Induced Acute Lung Injury in Mice. | 2016 | Inflammation | pmid:26276127 |