3-O-Methylquercetin

3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.

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Introduction

To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 3-O-Methylquercetin?

3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin

MeSH term MeSH ID Detail
Cell Transformation, Neoplastic D002471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 3-O-Methylquercetin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 3-O-Methylquercetin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 3-O-Methylquercetin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 3-O-Methylquercetin?

There are no associated biomedical information in the current reference collection.

What genes are associated with 3-O-Methylquercetin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 3-O-Methylquercetin?

Streptozotocin Diabetes

Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with 3-O-Methylquercetin

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Authors Title Published Journal PubMed Link
Enomoto S et al. Inhibitory effect of traditional Turkish folk medicines on aldose reductase (AR) and hematological activity, and on AR inhibitory activity of quercetin-3-O-methyl ether isolated from Cistus laurifolius L. 2004 Biol. Pharm. Bull. pmid:15256757
Oh SM and Chung KH Estrogenic activities of Ginkgo biloba extracts. 2004 Life Sci. pmid:14706564
Hong YJ and Mitchell AE Metabolic profiling of flavonol metabolites in human urine by liquid chromatography and tandem mass spectrometry. 2004 J. Agric. Food Chem. pmid:15506818
Ko WC et al. Suppressive effects of 3-O-methylquercetin on ovalbumin-induced airway hyperresponsiveness. 2004 Planta Med. pmid:15643544
Justino GC et al. Plasma quercetin metabolites: structure-antioxidant activity relationships. 2004 Arch. Biochem. Biophys. pmid:15519302
Wang Y et al. Simultaneous determination of quercetin, kaempferol and isorhamnetin accumulated human breast cancer cells, by high-performance liquid chromatography. 2005 J Pharm Biomed Anal pmid:15905060
Wang Y et al. Involvement of P-glycoprotein in regulating cellular levels of Ginkgo flavonols: quercetin, kaempferol, and isorhamnetin. 2005 J. Pharm. Pharmacol. pmid:15969930
Oh HM et al. Inhibitory activity of isorhamnetin from Persicaria thunbergii on Farnesyl Protein Transferase. 2005 Arch. Pharm. Res. pmid:15789745
Bonaccorsi P et al. Flavonol glucoside profile of southern Italian red onion (Allium cepa L.). 2005 J. Agric. Food Chem. pmid:15796618
Kim BG et al. Multiple regiospecific methylations of a flavonoid by plant O-methyltransferases expressed in E. coli. 2005 Biotechnol. Lett. pmid:16328980
Schulz HU et al. Investigation of pharmacokinetic data of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin revealed from single and multiple oral dose studies with a hypericum extract containing tablet in healthy male volunteers. 2005 Arzneimittelforschung pmid:16294501
Schulz HU et al. Investigation of the bioavailability of hypericin, pseudohypericin, hyperforin and the flavonoids quercetin and isorhamnetin following single and multiple oral dosing of a hypericum extract containing tablet. 2005 Arzneimittelforschung pmid:15727160
Lee YS et al. Inhibitory effects of isorhamnetin-3-O-beta-D-glucoside from Salicornia herbacea on rat lens aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues. 2005 Biol. Pharm. Bull. pmid:15863906
Gray D et al. Determination of flavonol aglycones in Ginkgo biloba dietary supplement crude materials and finished products by high-performance liquid chromatography: single laboratory validation. 2005 May-Jun J AOAC Int pmid:16001841
Suomela JP et al. Absorption of flavonols derived from sea buckthorn (Hippophaë rhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans. 2006 J. Agric. Food Chem. pmid:16968106
Bao M and Lou Y Isorhamnetin prevent endothelial cell injuries from oxidized LDL via activation of p38MAPK. 2006 Eur. J. Pharmacol. pmid:16963021
Hubbard GP et al. Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man: a pilot study. 2006 Br. J. Nutr. pmid:16925853
Dragoni S et al. Red wine alcohol promotes quercetin absorption and directs its metabolism towards isorhamnetin and tamarixetin in rat intestine in vitro. 2006 Br. J. Pharmacol. pmid:16444288
Ding S et al. Quantitative determination of major active components in Ginkgo biloba dietary supplements by liquid chromatography/mass spectrometry. 2006 Rapid Commun. Mass Spectrom. pmid:16921563
Shukla SK et al. Protection from radiation-induced mitochondrial and genomic DNA damage by an extract of Hippophae rhamnoides. 2006 Environ. Mol. Mutagen. pmid:16948057