MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Hu S et al. | Isorhamnetin inhibits cell proliferation and induces apoptosis in breast cancer via Akt and mitogen‑activated protein kinase kinase signaling pathways. | 2015 | Mol Med Rep | pmid:26502751 |
Park YJ et al. | Inhibitory Aromatase Effects of Flavonoids from Ginkgo Biloba Extracts on Estrogen Biosynthesis. | 2015 | Asian Pac. J. Cancer Prev. | pmid:26434836 |
Ruan Y et al. | Autophagy inhibition enhances isorhamnetin‑induced mitochondria‑dependent apoptosis in non‑small cell lung cancer cells. | 2015 | Mol Med Rep | pmid:26238746 |
Cariddi LN et al. | In Vitro and In Vivo Cytogenotoxic Effects of Hot Aqueous Extract of Achyrocline satureioides (Lam.) DC. | 2015 | Biomed Res Int | pmid:26078941 |
Chen TL et al. | Protective effects of isorhamnetin on apoptosis and inflammation in TNF-α-induced HUVECs injury. | 2015 | Int J Clin Exp Pathol | pmid:26045738 |
Sun Q et al. | Urinary Excretion of Select Dietary Polyphenol Metabolites Is Associated with a Lower Risk of Type 2 Diabetes in Proximate but Not Remote Follow-Up in a Prospective Investigation in 2 Cohorts of US Women. | 2015 | J. Nutr. | pmid:25904735 |
Li Q et al. | Anti-proliferation effects of isorhamnetin on lung cancer cells in vitro and in vivo. | 2015 | Asian Pac. J. Cancer Prev. | pmid:25854402 |
Antunes-Ricardo M et al. | Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica. | 2015 | Biomed Res Int | pmid:25821823 |
Abdal Dayem A et al. | Antiviral effect of methylated flavonol isorhamnetin against influenza. | 2015 | PLoS ONE | pmid:25806943 |
Luo Y et al. | Isorhamnetin attenuates atherosclerosis by inhibiting macrophage apoptosis via PI3K/AKT activation and HO-1 induction. | 2015 | PLoS ONE | pmid:25799286 |
Messer JG et al. | Quercetin Metabolites Up-Regulate the Antioxidant Response in Osteoblasts Isolated From Fetal Rat Calvaria. | 2015 | J. Cell. Biochem. | pmid:25716194 |
Jimenez R et al. | Quercetin and its metabolites inhibit the membrane NADPH oxidase activity in vascular smooth muscle cells from normotensive and spontaneously hypertensive rats. | 2015 | Food Funct | pmid:25562607 |
Xie Y et al. | Comparison of isorhamnetin absorption properties in total flavones of Hippophae rhamnoides L. with its pure form in a Caco-2 cell model mediated by multidrug resistance-associated protein. | 2015 | Eur J Pharm Sci | pmid:25813735 |
Maciej J et al. | Bioavailability of the flavonol quercetin in neonatal calves after oral administration of quercetin aglycone or rutin. | 2015 | J. Dairy Sci. | pmid:25795488 |
Shaheen N et al. | Separation of isorhamnetin 3-sulphate and astragalin from Flaveria bidentis (L.) Kuntze using macroporous resin and followed by high-speed countercurrent chromatography. | 2015 | J Sep Sci | pmid:25763770 |
Wiczkowski W et al. | Quercetin and isorhamnetin aglycones are the main metabolites of dietary quercetin in cerebrospinal fluid. | 2015 | Mol Nutr Food Res | pmid:25727325 |
RodrÃguez-RodrÃguez C et al. | The effect of isorhamnetin glycosides extracted from Opuntia ficus-indica in a mouse model of diet induced obesity. | 2015 | Food Funct | pmid:25588195 |
Wang H et al. | A phospholipid complex to improve the oral bioavailability of flavonoids. | 2015 | Drug Dev Ind Pharm | pmid:25496311 |
Mihajlovic L et al. | Composition of polyphenol and polyamide compounds in common ragweed (Ambrosia artemisiifolia L.) pollen and sub-pollen particles. | 2015 | Phytochemistry | pmid:25468540 |
Wang W et al. | Enhanced dissolution rate and oral bioavailability of Ginkgo biloba extract by preparing solid dispersion via hot-melt extrusion. | 2015 | Fitoterapia | pmid:25446043 |