MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Choi KC et al. | Inhibitory effects of quercetin on aflatoxin B1-induced hepatic damage in mice. | 2010 | Food Chem. Toxicol. | pmid:20621152 |
Holzschuh MH et al. | Identification and stability of a new bichalcone in Achyrocline satureioides spray dried powder. | 2010 | Pharmazie | pmid:21038841 |
Garrido I et al. | Targeted analysis of conjugated and microbial-derived phenolic metabolites in human urine after consumption of an almond skin phenolic extract. | 2010 | J. Nutr. | pmid:20739450 |
Raja MK et al. | A comprehensive review on Nymphaea stellata: A traditionally used bitter. | 2010 | J Adv Pharm Technol Res | pmid:22247863 |
Fernández-López JA et al. | Determination of antioxidant constituents in cactus pear fruits. | 2010 | Plant Foods Hum Nutr | pmid:20811778 |
Ozgen U et al. | A new sulfated alpha-ionone glycoside from Sonchus erzincanicus Matthews. | 2010 | Molecules | pmid:20428066 |
Cao J et al. | The relationship between fasting plasma concentrations of selected flavonoids and their ordinary dietary intake. | 2010 | Br. J. Nutr. | pmid:19747418 |
Rupasinghe HP et al. | Absorption and tissue distribution of dietary quercetin and quercetin glycosides of apple skin in broiler chickens. | 2010 | J. Sci. Food Agric. | pmid:20393998 |
An D et al. | Changes of metabolic profiles in urine after oral administration of quercetin in rats. | 2010 | Food Chem. Toxicol. | pmid:20304023 |
Rangel-Ordóñez L et al. | Plasma levels and distribution of flavonoids in rat brain after single and repeated doses of standardized Ginkgo biloba extract EGb 761®. | 2010 | Planta Med. | pmid:20486074 |
Chen ZP et al. | Comparative pharmacokinetics and bioavailability studies of quercetin, kaempferol and isorhamnetin after oral administration of Ginkgo biloba extracts, Ginkgo biloba extract phospholipid complexes and Ginkgo biloba extract solid dispersions in rats. | 2010 | Fitoterapia | pmid:20603197 |
Qu L et al. | Protective effects of flavonoids against oxidative stress induced by simulated microgravity in SH-SY5Y cells. | 2010 | Neurochem. Res. | pmid:20571914 |
Park S and Choi J | Inhibition of beta-catenin/Tcf signaling by flavonoids. | 2010 | J. Cell. Biochem. | pmid:20564233 |
Lee J et al. | Isorhamnetin-induced anti-adipogenesis is mediated by stabilization of beta-catenin protein. | 2010 | Life Sci. | pmid:20097210 |
Olsson ME et al. | Quercetin and isorhamnetin in sweet and red cultivars of onion (Allium cepa L.) at harvest, after field curing, heat treatment, and storage. | 2010 | J. Agric. Food Chem. | pmid:20099844 |
Jaramillo S et al. | The flavonol isorhamnetin exhibits cytotoxic effects on human colon cancer cells. | 2010 | J. Agric. Food Chem. | pmid:20923189 |
Wang J et al. | Preparative separation of phenolic compounds from Halimodendron halodendron by high-speed counter-current chromatography. | 2010 | Molecules | pmid:20877205 |
Xia F et al. | Simultaneous determination of copper, lead, and cadmium at hexagonal mesoporous silica immobilized quercetin modified carbon paste electrode. | 2010 | J Autom Methods Manag Chem | pmid:20445747 |
Krenn L et al. | Contribution of methylated exudate flavonoids to the anti-inflammatory activity of Grindelia robusta. | 2009 | Fitoterapia | pmid:19278665 |
Winterbone MS et al. | Physiologically relevant metabolites of quercetin have no effect on adhesion molecule or chemokine expression in human vascular smooth muscle cells. | 2009 | Atherosclerosis | pmid:18489909 |
Li L et al. | Identification and bioactivities of resveratrol oligomers and flavonoids from Carex folliculata seeds. | 2009 | J. Agric. Food Chem. | pmid:19627089 |
Søltoft M et al. | Pressurised liquid extraction of flavonoids in onions. Method development and validation. | 2009 | Talanta | pmid:19782226 |
Kawai Y et al. | Different profiles of quercetin metabolites in rat plasma: comparison of two administration methods. | 2009 | Biosci. Biotechnol. Biochem. | pmid:19270373 |
Matsukawa N et al. | Nondigestible saccharides suppress the bacterial degradation of quercetin aglycone in the large intestine and enhance the bioavailability of quercetin glucoside in rats. | 2009 | J. Agric. Food Chem. | pmid:19807098 |
Okoko T and Oruambo IF | Inhibitory activity of quercetin and its metabolite on lipopolysaccharide-induced activation of macrophage U937 cells. | 2009 | Food Chem. Toxicol. | pmid:19271315 |
Lodi F et al. | Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta. | 2009 | Atherosclerosis | pmid:18801486 |
Lee J et al. | Isorhamnetin represses adipogenesis in 3T3-L1 cells. | 2009 | Obesity (Silver Spring) | pmid:18948972 |
Larmo PS et al. | Effect of a low dose of sea buckthorn berries on circulating concentrations of cholesterol, triacylglycerols, and flavonols in healthy adults. | 2009 | Eur J Nutr | pmid:19288149 |
Wang Z et al. | Simultaneous determination of six herbal components in intestinal perfusate by high-performance liquid chromatography. | 2009 | Biomed. Chromatogr. | pmid:19309764 |
Hölscher D et al. | Matrix-free UV-laser desorption/ionization (LDI) mass spectrometric imaging at the single-cell level: distribution of secondary metabolites of Arabidopsis thaliana and Hypericum species. | 2009 | Plant J. | pmid:19732382 |
Boesch-Saadatmandi C et al. | Effect of apoE genotype and dietary quercetin on blood lipids and TNF-alpha levels in apoE3 and apoE4 targeted gene replacement mice. | 2009 | Br. J. Nutr. | pmid:18986596 |
Pengfei L et al. | Antioxidant properties of isolated isorhamnetin from the sea buckthorn marc. | 2009 | Plant Foods Hum Nutr | pmid:19444611 |
Fasolo D et al. | Development of topical nanoemulsions containing quercetin and 3-O-methylquercetin. | 2009 | Pharmazie | pmid:20099516 |
Romero M et al. | Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKC. | 2009 | Atherosclerosis | pmid:18436224 |
Vukics V et al. | Analysis of heartsease (Viola tricolor L.) flavonoid glycosides by micro-liquid chromatography coupled to multistage mass spectrometry. | 2008 | J Chromatogr A | pmid:18514209 |
Wang XM et al. | Two new flavonol glycosides from Sarcopyramis bodinieri var. delicate. | 2008 | Molecules | pmid:18596665 |
Papiez MA et al. | The changes of antioxidant defense system caused by quercetin administration do not lead to DNA damage and apoptosis in the spleen and bone marrow cells of rats. | 2008 | Food Chem. Toxicol. | pmid:18602965 |
Paulke A et al. | St. John's wort flavonoids and their metabolites show antidepressant activity and accumulate in brain after multiple oral doses. | 2008 | Pharmazie | pmid:18468390 |
Olszewska M | Separation of quercetin, sexangularetin, kaempferol and isorhamnetin for simultaneous HPLC determination of flavonoid aglycones in inflorescences, leaves and fruits of three Sorbus species. | 2008 | J Pharm Biomed Anal | pmid:18635332 |
Bieger J et al. | Tissue distribution of quercetin in pigs after long-term dietary supplementation. | 2008 | J. Nutr. | pmid:18641184 |
Lee HJ et al. | Mitochondria-cytochrome C-caspase-9 cascade mediates isorhamnetin-induced apoptosis. | 2008 | Cancer Lett. | pmid:18617322 |
Egert S et al. | Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans. | 2008 | J. Nutr. | pmid:18716159 |
Lee SU et al. | Flavonoid content in fresh, home-processed, and light-exposed onions and in dehydrated commercial onion products. | 2008 | J. Agric. Food Chem. | pmid:18759442 |
Neznanov N et al. | Quercetinase pirin makes poliovirus replication resistant to flavonoid quercetin. | 2008 | DNA Cell Biol. | pmid:18067462 |
Liu AL et al. | Study of the electrochemical behavior of isorhamnetin on a glassy carbon electrode and its application. | 2008 | Talanta | pmid:18804639 |
Lan K et al. | Intra-herb pharmacokinetics interaction between quercetin and isorhamentin. | 2008 | Acta Pharmacol. Sin. | pmid:18954533 |
Suzuki H et al. | Metabolic profiling of flavonoids in Lotus japonicus using liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry. | 2008 | Phytochemistry | pmid:17669449 |
Steffen Y et al. | Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. | 2008 | Arch. Biochem. Biophys. | pmid:17996190 |
Kim JY et al. | In vitro anti-inflammatory activity of 3-O-methyl-flavones isolated from Siegesbeckia glabrescens. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18178435 |
Sobolev VS et al. | Spermidine and flavonoid conjugates from peanut (Arachis hypogaea) flowers. | 2008 | J. Agric. Food Chem. | pmid:18412366 |