MeSH term | MeSH ID | Detail |
---|---|---|
Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
---|---|---|
Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Wang Z et al. | Simultaneous determination of six herbal components in intestinal perfusate by high-performance liquid chromatography. | 2009 | Biomed. Chromatogr. | pmid:19309764 |
Qiu L et al. | Protective effects of isorhamnetin on N2a cell against endoplasmic reticulum stress-induced injury is mediated by PKCε. | 2017 | Biomed. Pharmacother. | pmid:28715866 |
Lu X et al. | Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice. | 2018 | Biomed. Pharmacother. | pmid:29684859 |
Kim JY et al. | In vitro anti-inflammatory activity of 3-O-methyl-flavones isolated from Siegesbeckia glabrescens. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18178435 |
Si YX et al. | Effects of isorhamnetin on tyrosinase: inhibition kinetics and computational simulation. | 2012 | Biosci. Biotechnol. Biochem. | pmid:22790928 |
Igarashi K and Ohmuma M | Effects of isorhamnetin, rhamnetin, and quercetin on the concentrations of cholesterol and lipoperoxide in the serum and liver and on the blood and liver antioxidative enzyme activities of rats. | 1995 | Biosci. Biotechnol. Biochem. | pmid:7772823 |
Kawai Y et al. | Different profiles of quercetin metabolites in rat plasma: comparison of two administration methods. | 2009 | Biosci. Biotechnol. Biochem. | pmid:19270373 |
Azuma K et al. | Enhancing effect of lipids and emulsifiers on the accumulation of quercetin metabolites in blood plasma after the short-term ingestion of onion by rats. | 2003 | Biosci. Biotechnol. Biochem. | pmid:14730132 |
Iida A et al. | Protective effects of Nitraria retusa extract and its constituent isorhamnetin against amyloid β-induced cytotoxicity and amyloid β aggregation. | 2015 | Biosci. Biotechnol. Biochem. | pmid:25965116 |
Saito A et al. | Protective effects of quercetin and its metabolites on H2O2-induced chromosomal damage to WIL2-NS cells. | 2004 | Biosci. Biotechnol. Biochem. | pmid:14981287 |