MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Li YC et al. | Luteolin Suppresses Inflammatory Mediator Expression by Blocking the Akt/NFκB Pathway in Acute Lung Injury Induced by Lipopolysaccharide in Mice. | 2012 | Evid Based Complement Alternat Med | pmid:22203870 |
Zhang N et al. | Isorhamnetin protects rat ventricular myocytes from ischemia and reperfusion injury. | 2011 | Exp. Toxicol. Pathol. | pmid:19815400 |
da Silva EL et al. | Quercetin metabolites inhibit copper ion-induced lipid peroxidation in rat plasma. | 1998 | FEBS Lett. | pmid:9688581 |
Lall N et al. | Antiviral and antituberculous activity of Helichrysum melanacme constituents. | 2006 | Fitoterapia | pmid:16529879 |
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Granica S et al. | Antioxidant and anti-inflammatory flavonol glucuronides from Polygonum aviculare L. | 2013 | Fitoterapia | pmid:24028968 |
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Wang W et al. | Enhanced dissolution rate and oral bioavailability of Ginkgo biloba extract by preparing solid dispersion via hot-melt extrusion. | 2015 | Fitoterapia | pmid:25446043 |
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Xie Y et al. | Phytic acid enhances the oral absorption of isorhamnetin, quercetin, and kaempferol in total flavones of Hippophae rhamnoides L. | 2014 | Fitoterapia | pmid:24462958 |
Li G et al. | Pharmacokinetic properties of isorhamnetin, kaempferol and quercetin after oral gavage of total flavones of Hippophae rhamnoides L. in rats using a UPLC-MS method. | 2012 | Fitoterapia | pmid:22056665 |
Guo R et al. | Comparative assessment of phytochemical profiles, antioxidant and antiproliferative activities of Sea buckthorn (Hippophaë rhamnoides L.) berries. | 2017 | Food Chem | pmid:27979305 |
Tian Y et al. | Phenolic compounds extracted by acidic aqueous ethanol from berries and leaves of different berry plants. | 2017 | Food Chem | pmid:27855899 |
Mudrić SŽ et al. | The polyphenolics and carbohydrates as indicators of botanical and geographical origin of Serbian autochthonous clones of red spice paprika. | 2017 | Food Chem | pmid:27664689 |
Ferreres F et al. | HPLC-DAD-ESI/MS(n) profiling of phenolic compounds from Lathyrus cicera L. seeds. | 2017 | Food Chem | pmid:27507525 |
Mata A et al. | Contribution to the characterization of Opuntia spp. juices by LC-DAD-ESI-MS/MS. | 2016 | Food Chem | pmid:27211682 |
Juániz I et al. | Influence of heat treatment on antioxidant capacity and (poly)phenolic compounds of selected vegetables. | 2016 | Food Chem | pmid:26616976 |
Liu H et al. | Solid-phase extraction of flavonoids in honey samples using carbamate-embedded triacontyl-modified silica sorbent. | 2016 | Food Chem | pmid:26988475 |
Yang JH et al. | O-Methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation. | 2013 | Food Chem. Toxicol. | pmid:23774260 |
Okoko T and Oruambo IF | Inhibitory activity of quercetin and its metabolite on lipopolysaccharide-induced activation of macrophage U937 cells. | 2009 | Food Chem. Toxicol. | pmid:19271315 |