MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Abdal Dayem A et al. | Antiviral effect of methylated flavonol isorhamnetin against influenza. | 2015 | PLoS ONE | pmid:25806943 |
Luo Y et al. | Isorhamnetin attenuates atherosclerosis by inhibiting macrophage apoptosis via PI3K/AKT activation and HO-1 induction. | 2015 | PLoS ONE | pmid:25799286 |
Dou W et al. | Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway. | 2014 | J. Nutr. Biochem. | pmid:24913217 |
Seo K et al. | The antioxidant effects of isorhamnetin contribute to inhibit COX-2 expression in response to inflammation: a potential role of HO-1. | 2014 | Inflammation | pmid:24337631 |
Yang JH et al. | Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24211276 |
Li C et al. | Isorhamnetin suppresses colon cancer cell growth through the PI3K‑Akt‑mTOR pathway. | 2014 | Mol Med Rep | pmid:24398569 |
Kawasaki T et al. | Components of foods inhibit a drug exporter, human multidrug and toxin extrusion transporter 1. | 2014 | Biol. Pharm. Bull. | pmid:24492725 |
Bidone J et al. | Simultaneous quantification of flavonoids from Achyrocline satureioides by a polar-reversed phase LC method--application to skin permeation/retention studies. | 2014 | Pharmazie | pmid:24601216 |
Somerset S and Papier K | A food frequency questionnaire validated for estimating dietary flavonoid intake in an Australian population. | 2014 | Nutr Cancer | pmid:25207829 |
Kim B et al. | Eruca sativa and its flavonoid components, quercetin and isorhamnetin, improve skin barrier function by activation of peroxisome proliferator-activated receptor (PPAR)-α and suppression of inflammatory cytokines. | 2014 | Phytother Res | pmid:24610745 |
Morris JB et al. | Flavonol content, oil%, and fatty acid composition variability in seeds of Teramnus labialis and T. uncinatus accessions with nutraceutical potential. | 2014 | J Diet Suppl | pmid:25054688 |
Antunes-Ricardo M et al. | Induction of apoptosis in colon cancer cells treated with isorhamnetin glycosides from Opuntia ficus-indica pads. | 2014 | Plant Foods Hum Nutr | pmid:25186940 |
Bakır T et al. | Antioxidant/prooxidant effects of α-tocopherol, quercetin and isorhamnetin on linoleic acid peroxidation induced by Cu(II) and H2O2. | 2014 | Int J Food Sci Nutr | pmid:24152374 |
Perez A et al. | The flavonoid quercetin induces acute vasodilator effects in healthy volunteers: correlation with beta-glucuronidase activity. | 2014 | Pharmacol. Res. | pmid:25076013 |
Dong GZ et al. | AMPK activation by isorhamnetin protects hepatocytes against oxidative stress and mitochondrial dysfunction. | 2014 | Eur. J. Pharmacol. | pmid:24972246 |
Jayashankar B et al. | Supercritical extract of Seabuckthorn Leaves (SCE200ET) inhibited endotoxemia by reducing inflammatory cytokines and nitric oxide synthase 2 expression. | 2014 | Int. Immunopharmacol. | pmid:24594274 |
Duan J et al. | Transport characteristics of isorhamnetin across intestinal Caco-2 cell monolayers and the effects of transporters on it. | 2014 | Food Chem. Toxicol. | pmid:24525098 |
Xie Y et al. | Phytic acid enhances the oral absorption of isorhamnetin, quercetin, and kaempferol in total flavones of Hippophae rhamnoides L. | 2014 | Fitoterapia | pmid:24462958 |
Kim JH et al. | Enzyme-assisted extraction of cactus bioactive molecules under high hydrostatic pressure. | 2014 | J. Sci. Food Agric. | pmid:23893871 |
Farag MA et al. | Metabolome classification of Brassica napus L. organs via UPLC-QTOF-PDA-MS and their anti-oxidant potential. | 2013 May-Jun | Phytochem Anal | pmid:23055344 |