| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Total
1
3-O-Methylquercetin
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
Cross Reference
Introduction
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 3-O-Methylquercetin?
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
PubChem Associated disorders and diseases
What pathways are associated with 3-O-Methylquercetin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 3-O-Methylquercetin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 3-O-Methylquercetin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 3-O-Methylquercetin?
There are no associated biomedical information in the current reference collection.
What genes are associated with 3-O-Methylquercetin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 3-O-Methylquercetin?
Streptozotocin Diabetes
Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with 3-O-Methylquercetin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Papiez MA et al. | The changes of antioxidant defense system caused by quercetin administration do not lead to DNA damage and apoptosis in the spleen and bone marrow cells of rats. | 2008 | Food Chem. Toxicol. | pmid:18602965 |
| Choi KC et al. | Inhibitory effects of quercetin on aflatoxin B1-induced hepatic damage in mice. | 2010 | Food Chem. Toxicol. | pmid:20621152 |
| Ferreres F et al. | Phenolic compounds from Jacaranda caroba (Vell.) A. DC.: approaches to neurodegenerative disorders. | 2013 | Food Chem. Toxicol. | pmid:23524314 |
| Yang JH et al. | O-Methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation. | 2013 | Food Chem. Toxicol. | pmid:23774260 |
| Sabini MC et al. | Evaluation of the cytotoxicity, genotoxicity and apoptotic induction of an aqueous extract of Achyrocline satureioides (Lam.) DC. | 2013 | Food Chem. Toxicol. | pmid:23948353 |
| An D et al. | Changes of metabolic profiles in urine after oral administration of quercetin in rats. | 2010 | Food Chem. Toxicol. | pmid:20304023 |
| Jimenez R et al. | Quercetin and its metabolites inhibit the membrane NADPH oxidase activity in vascular smooth muscle cells from normotensive and spontaneously hypertensive rats. | 2015 | Food Funct | pmid:25562607 |
| RodrÃguez-RodrÃguez C et al. | The effect of isorhamnetin glycosides extracted from Opuntia ficus-indica in a mouse model of diet induced obesity. | 2015 | Food Funct | pmid:25588195 |
| Surco-Laos F et al. | Effects of O-methylated metabolites of quercetin on oxidative stress, thermotolerance, lifespan and bioavailability on Caenorhabditis elegans. | 2011 | Food Funct | pmid:21776484 |
| Cornish KM et al. | Quercetin metabolism in the lens: role in inhibition of hydrogen peroxide induced cataract. | 2002 | Free Radic. Biol. Med. | pmid:12086683 |
| Ader P et al. | Bioavailability and metabolism of the flavonol quercetin in the pig. | 2000 | Free Radic. Biol. Med. | pmid:10832067 |
| Choi YH | The cytoprotective effect of isorhamnetin against oxidative stress is mediated by the upregulation of the Nrf2-dependent HO-1 expression in C2C12 myoblasts through scavenging reactive oxygen species and ERK inactivation. | 2016 | Gen. Physiol. Biophys. | pmid:26830132 |
| Zhao TT et al. | Isorhamnetin protects against hypoxia/reoxygenation-induced injure by attenuating apoptosis and oxidative stress in H9c2 cardiomyocytes. | 2018 | Gene | pmid:29730426 |
| Chen JH et al. | Estrogenic effects of flavonoid components in Xiaoyao powder. | 2016 | Genet. Mol. Res. | pmid:26909969 |
| Chi G et al. | Isorhamnetin protects mice from lipopolysaccharide-induced acute lung injury via the inhibition of inflammatory responses. | 2016 | Inflamm. Res. | pmid:26525359 |
| Seo K et al. | The antioxidant effects of isorhamnetin contribute to inhibit COX-2 expression in response to inflammation: a potential role of HO-1. | 2014 | Inflammation | pmid:24337631 |
| Li Y et al. | Isorhamnetin ameliorates LPS-induced inflammatory response through downregulation of NF-κB signaling. | 2016 | Inflammation | pmid:27138362 |
| Yang B et al. | Protective Effect of Isorhamnetin on Lipopolysaccharide-Induced Acute Lung Injury in Mice. | 2016 | Inflammation | pmid:26276127 |
| Chen TL et al. | Protective effects of isorhamnetin on apoptosis and inflammation in TNF-α-induced HUVECs injury. | 2015 | Int J Clin Exp Pathol | pmid:26045738 |
| Zhang BY et al. | Isorhamnetin flavonoid synergistically enhances the anticancer activity and apoptosis induction by cis-platin and carboplatin in non-small cell lung carcinoma (NSCLC). | 2015 | Int J Clin Exp Pathol | pmid:25755690 |