MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Jiang JS et al. | Mechanisms of suppression of nitric oxide production by 3-O-methylquercetin in RAW 264.7 cells. | 2006 | J Ethnopharmacol | pmid:16213685 |
Küpeli E et al. | Effect of Cistus laurifolius L. leaf extracts and flavonoids on acetaminophen-induced hepatotoxicity in mice. | 2006 | J Ethnopharmacol | pmid:16216454 |
Chawla R et al. | Radioprotective and antioxidant activity of fractionated extracts of berries of Hippophae rhamnoides. | 2007 | J Med Food | pmid:17472473 |
Shi W et al. | Bioactive flavonoids from Flos Sophorae. | 2017 | J Nat Med | pmid:28357634 |
Yamauchi K and Mitsunaga T | Methylquercetins stimulate melanin biosynthesis in a three-dimensional skin model. | 2018 | J Nat Med | pmid:29442220 |
Wang Y et al. | Simultaneous determination of quercetin, kaempferol and isorhamnetin accumulated human breast cancer cells, by high-performance liquid chromatography. | 2005 | J Pharm Biomed Anal | pmid:15905060 |
Zu Y et al. | Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD. | 2006 | J Pharm Biomed Anal | pmid:16520013 |
Granica S et al. | Novel insight into qualitative standardization of Polygoni avicularis herba (Ph. Eur.). | 2013 | J Pharm Biomed Anal | pmid:23021006 |
Olszewska M | Separation of quercetin, sexangularetin, kaempferol and isorhamnetin for simultaneous HPLC determination of flavonoid aglycones in inflorescences, leaves and fruits of three Sorbus species. | 2008 | J Pharm Biomed Anal | pmid:18635332 |
He J et al. | A sensitive LC-MS/MS method for simultaneous determination of six flavonoids in rat plasma: application to a pharmacokinetic study of total flavonoids from mulberry leaves. | 2013 | J Pharm Biomed Anal | pmid:23850933 |
De Souza KC et al. | LC determination of flavonoids: separation of quercetin, luteolin and 3-O-methylquercetin in Achyrocline satureioides preparations. | 2002 | J Pharm Biomed Anal | pmid:12008157 |
Fasolo D et al. | Validation of an isocratic LC method for determination of quercetin and methylquercetin in topical nanoemulsions. | 2007 | J Pharm Biomed Anal | pmid:17540529 |
Dubber MJ and Kanfer I | High-performance liquid chromatographic determination of selected flavonols in Ginkgo biloba solid oral dosage forms. | 2004 | J Pharm Pharm Sci | pmid:15576009 |
Shaheen N et al. | Separation of isorhamnetin 3-sulphate and astragalin from Flaveria bidentis (L.) Kuntze using macroporous resin and followed by high-speed countercurrent chromatography. | 2015 | J Sep Sci | pmid:25763770 |
Xie Q et al. | Separation and purification of isorhamnetin 3-sulphate from Flaveria bidentis (L.) Kuntze by counter-current chromatography comparing two kinds of solvent systems. | 2012 | J Sep Sci | pmid:22084024 |
Fattorusso E et al. | Chemical composition of shallot (Allium ascalonicum Hort.). | 2002 | J. Agric. Food Chem. | pmid:12236699 |
Frison S and Sporns P | Variation in the flavonol glycoside composition of almond seedcoats as determined by maldi-tof mass spectrometry. | 2002 | J. Agric. Food Chem. | pmid:12405781 |
Sobolev VS et al. | Spermidine and flavonoid conjugates from peanut (Arachis hypogaea) flowers. | 2008 | J. Agric. Food Chem. | pmid:18412366 |
Hong YJ and Mitchell AE | Metabolic profiling of flavonol metabolites in human urine by liquid chromatography and tandem mass spectrometry. | 2004 | J. Agric. Food Chem. | pmid:15506818 |
Rajbhandari R et al. | Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometry. | 2011 | J. Agric. Food Chem. | pmid:21634376 |