3-O-Methylquercetin

3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.

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Introduction

To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 3-O-Methylquercetin?

3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin

MeSH term MeSH ID Detail
Cell Transformation, Neoplastic D002471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 3-O-Methylquercetin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 3-O-Methylquercetin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 3-O-Methylquercetin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 3-O-Methylquercetin?

There are no associated biomedical information in the current reference collection.

What genes are associated with 3-O-Methylquercetin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 3-O-Methylquercetin?

Streptozotocin Diabetes

Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with 3-O-Methylquercetin

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Authors Title Published Journal PubMed Link
Jiang JS et al. Mechanisms of suppression of nitric oxide production by 3-O-methylquercetin in RAW 264.7 cells. 2006 J Ethnopharmacol pmid:16213685
Küpeli E et al. Effect of Cistus laurifolius L. leaf extracts and flavonoids on acetaminophen-induced hepatotoxicity in mice. 2006 J Ethnopharmacol pmid:16216454
Chawla R et al. Radioprotective and antioxidant activity of fractionated extracts of berries of Hippophae rhamnoides. 2007 J Med Food pmid:17472473
Shi W et al. Bioactive flavonoids from Flos Sophorae. 2017 J Nat Med pmid:28357634
Yamauchi K and Mitsunaga T Methylquercetins stimulate melanin biosynthesis in a three-dimensional skin model. 2018 J Nat Med pmid:29442220
Wang Y et al. Simultaneous determination of quercetin, kaempferol and isorhamnetin accumulated human breast cancer cells, by high-performance liquid chromatography. 2005 J Pharm Biomed Anal pmid:15905060
Zu Y et al. Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD. 2006 J Pharm Biomed Anal pmid:16520013
Granica S et al. Novel insight into qualitative standardization of Polygoni avicularis herba (Ph. Eur.). 2013 J Pharm Biomed Anal pmid:23021006
Olszewska M Separation of quercetin, sexangularetin, kaempferol and isorhamnetin for simultaneous HPLC determination of flavonoid aglycones in inflorescences, leaves and fruits of three Sorbus species. 2008 J Pharm Biomed Anal pmid:18635332
He J et al. A sensitive LC-MS/MS method for simultaneous determination of six flavonoids in rat plasma: application to a pharmacokinetic study of total flavonoids from mulberry leaves. 2013 J Pharm Biomed Anal pmid:23850933
De Souza KC et al. LC determination of flavonoids: separation of quercetin, luteolin and 3-O-methylquercetin in Achyrocline satureioides preparations. 2002 J Pharm Biomed Anal pmid:12008157
Fasolo D et al. Validation of an isocratic LC method for determination of quercetin and methylquercetin in topical nanoemulsions. 2007 J Pharm Biomed Anal pmid:17540529
Dubber MJ and Kanfer I High-performance liquid chromatographic determination of selected flavonols in Ginkgo biloba solid oral dosage forms. 2004 J Pharm Pharm Sci pmid:15576009
Shaheen N et al. Separation of isorhamnetin 3-sulphate and astragalin from Flaveria bidentis (L.) Kuntze using macroporous resin and followed by high-speed countercurrent chromatography. 2015 J Sep Sci pmid:25763770
Xie Q et al. Separation and purification of isorhamnetin 3-sulphate from Flaveria bidentis (L.) Kuntze by counter-current chromatography comparing two kinds of solvent systems. 2012 J Sep Sci pmid:22084024
Fattorusso E et al. Chemical composition of shallot (Allium ascalonicum Hort.). 2002 J. Agric. Food Chem. pmid:12236699
Frison S and Sporns P Variation in the flavonol glycoside composition of almond seedcoats as determined by maldi-tof mass spectrometry. 2002 J. Agric. Food Chem. pmid:12405781
Sobolev VS et al. Spermidine and flavonoid conjugates from peanut (Arachis hypogaea) flowers. 2008 J. Agric. Food Chem. pmid:18412366
Hong YJ and Mitchell AE Metabolic profiling of flavonol metabolites in human urine by liquid chromatography and tandem mass spectrometry. 2004 J. Agric. Food Chem. pmid:15506818
Rajbhandari R et al. Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometry. 2011 J. Agric. Food Chem. pmid:21634376