MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Fasolo D et al. | Validation of an isocratic LC method for determination of quercetin and methylquercetin in topical nanoemulsions. | 2007 | J Pharm Biomed Anal | pmid:17540529 |
Tundis R et al. | Inhibitory effects on the digestive enzyme alpha-amylase of three Salsola species (Chenopodiaceae) in vitro. | 2007 | Pharmazie | pmid:17663200 |
Suzuki H et al. | Metabolic profiling of flavonoids in Lotus japonicus using liquid chromatography Fourier transform ion cyclotron resonance mass spectrometry. | 2008 | Phytochemistry | pmid:17669449 |
Jiang JS et al. | Potent suppressive effects of 3-O-methylquercetin 5,7,3',4'-O-tetraacetate on ovalbumin-induced airway hyperresponsiveness. | 2007 | Planta Med. | pmid:17823872 |
Steffen Y et al. | Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase. | 2008 | Arch. Biochem. Biophys. | pmid:17996190 |
Tamura M et al. | Effect of pectin enhancement on plasma quercetin and fecal flora in rutin-supplemented mice. | 2007 | J. Food Sci. | pmid:18034749 |
Neznanov N et al. | Quercetinase pirin makes poliovirus replication resistant to flavonoid quercetin. | 2008 | DNA Cell Biol. | pmid:18067462 |
Kim JY et al. | In vitro anti-inflammatory activity of 3-O-methyl-flavones isolated from Siegesbeckia glabrescens. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18178435 |
Holzschuh MH et al. | Thermal and photo stability of phenolic constituents of an Achyrocline satureioides spray-dried powder. | 2007 | Pharmazie | pmid:18214340 |
Hämäläinen M et al. | Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. | 2007 | Mediators Inflamm. | pmid:18274639 |