MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.
To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin
MeSH term | MeSH ID | Detail |
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Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ku SK et al. | Anticoagulant activities of persicarin and isorhamnetin. | 2013 | Vascul. Pharmacol. | pmid:23391847 |
Östlund J et al. | In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent. | 2017 | Toxicology | pmid:28232125 |
Yang JH et al. | Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24211276 |
Chang TK et al. | Effect of Ginkgo biloba extract on procarcinogen-bioactivating human CYP1 enzymes: identification of isorhamnetin, kaempferol, and quercetin as potent inhibitors of CYP1B1. | 2006 | Toxicol. Appl. Pharmacol. | pmid:16226778 |
Søltoft M et al. | Pressurised liquid extraction of flavonoids in onions. Method development and validation. | 2009 | Talanta | pmid:19782226 |
Liu AL et al. | Study of the electrochemical behavior of isorhamnetin on a glassy carbon electrode and its application. | 2008 | Talanta | pmid:18804639 |
Zhang Y et al. | Dietary component isorhamnetin is a PPARγ antagonist and ameliorates metabolic disorders induced by diet or leptin deficiency. | 2016 | Sci Rep | pmid:26775807 |
Ding S et al. | Quantitative determination of major active components in Ginkgo biloba dietary supplements by liquid chromatography/mass spectrometry. | 2006 | Rapid Commun. Mass Spectrom. | pmid:16921563 |
Lan K et al. | Quantitative determination of isorhamnetin, quercetin and kaempferol in rat plasma by liquid chromatography with electrospray ionization tandem mass spectrometry and its application to the pharmacokinetic study of isorhamnetin. | 2007 | Rapid Commun. Mass Spectrom. | pmid:17154349 |
Sun J et al. | Isorhamnetin protects against doxorubicin-induced cardiotoxicity in vivo and in vitro. | 2013 | PLoS ONE | pmid:23724057 |