Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Edema, Cardiac D004489 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Radiculopathy D011843 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Bluetongue D001819 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Calzada C et al. 12(S)-Hydroperoxy-eicosatetraenoic acid increases arachidonic acid availability in collagen-primed platelets. 2001 J. Lipid Res. pmid:11518767
Dowd NP et al. Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo. 2001 J. Clin. Invest. pmid:11518732
Muramatsu H et al. [Correlation between the clinical effects of Seratrodast and the level of 11-dehydrothromboxane B2 in urine/sputum in bronchial asthma patients]. 2001 Arerugi pmid:11517517
Takeyoshi I et al. The effect of a selective cyclooxygenase-2 inhibitor in extended liver resection with ischemia in dogs. 2001 J. Surg. Res. pmid:11516201
Bölke E et al. Changes of gut barrier function during anesthesia and cardiac surgery. 2001 Angiology pmid:11515987
Tomida T et al. Altered expression of prostacyclin synthase in a subset of the thick ascending limb cells and mesangial cells in 5/6-nephrectomized rats. 2001 Hypertens. Res. pmid:11510754
Diebolt M et al. Wine polyphenols decrease blood pressure, improve NO vasodilatation, and induce gene expression. 2001 Hypertension pmid:11509469
Ploner F et al. Effects of combined selective iNOS inhibition and peroxynitrite blockade during endotoxemia in pigs. 2001 Shock pmid:11508865
Wang W et al. Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. 2000 Acta Pharmacol. Sin. pmid:11501172
Chen G et al. [The effect of the molecular triggers of hemostatic activity on thrombosis in early stage of electrical injuries]. 1999 Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi pmid:11501103
Khan HH et al. Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs. 2000 Acta Pharmacol. Sin. pmid:11501061
Valeri CR et al. Anemia-induced increase in the bleeding time: implications for treatment of nonsurgical blood loss. 2001 Transfusion pmid:11493727
Rebrov BA [Role of thromboxane A2 (B2) in the pathogenesis of stress proteinuria in healthy persons]. 2001 Mar-Apr Urologiia pmid:11490711
Urquhart P et al. Profile of eicosanoids produced by human saphenous vein endothelial cells and the effect of dietary fatty acids. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11487303
Xu J et al. [Study on relativity between oxygen free radical and thromboxane B2, 6-keto-PGF1 alpha during ligustrazine treatment of intrauterine growth retardation]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11477921
Huang R et al. [Effects in tetramethylpyrazine on TXA2 and PGI2 by cardio-pulmonary bypass in congenital heart diseases with pulmonary hypertension patients]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11477904
Lin S et al. [Clinical study on active factors of vascular endothelial cells in acute cerebral infarction patients and therapeutical effect of activating blood stasis]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11477811
Lang J et al. [Comparative study on effect of Panax notoginseng and ticlid in treating early diabetic nephropathy]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11475719
Wu Y et al. [Clinical study on improving effect of Buyang Huanwu decoction on plasma thromboxane B2, 6-keto-prostaglandin F1 alpha, endothelin and calcitonin gene related peptide in primary nephrotic syndrome patients]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11475715
Zoja C et al. Mycophenolate mofetil combined with a cyclooxygenase-2 inhibitor ameliorates murine lupus nephritis. 2001 Kidney Int. pmid:11473648
Catella-Lawson F et al. Oral glycoprotein IIb/IIIa antagonism in patients with coronary artery disease. 2001 Am. J. Cardiol. pmid:11472700
Rosón MI et al. Serotonin hypersensitivity in aorta of two kidney-two clip hypertensive rats: calcium contribution and prostanoids-nitric oxide interactions. 2001 Arch. Physiol. Biochem. pmid:11471069
Wojakowski W and Gmiński J Plasma levels of von willebrand factor, endothelin-1, prostacyclin and thromboxane in children from families with high risk of premature coronary artery disease. 2001 Scand. J. Clin. Lab. Invest. pmid:11465346
Coelho-Filho OR et al. Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats. 2001 Int. J. Cardiol. pmid:11461744
Tran HS et al. Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock. 2001 Crit. Care Med. pmid:11445706
Dubé JN et al. Characterization of a partial prostaglandin endoperoxide H synthase-1 deficiency in a patient with a bleeding disorder. 2001 Br. J. Haematol. pmid:11442478
Gossmann J et al. Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide? 2001 Kidney Blood Press. Res. pmid:11435743
Minuz P et al. NCX4016 (NO-aspirin) inhibits thromboxane biosynthesis and tissue factor expression and activity in human monocytes. 2001 Jul-Aug Med. Sci. Monit. pmid:11433179
Oketani K et al. In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production. 2001 Eur. J. Pharmacol. pmid:11430933
Engström K et al. Effect of low-dose aspirin in combination with stable fish oil on whole blood production of eicosanoids. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11427037
Feldman M et al. Effects of low-dose aspirin on serum C-reactive protein and thromboxane B2 concentrations: a placebo-controlled study using a highly sensitive C-reactive protein assay. 2001 J. Am. Coll. Cardiol. pmid:11419884
Okita M et al. Effect of arachidonic acid-rich oil on lipids and arachidonate metabolites in ethanol- treated rats. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418023
Karamouzis M et al. The response of muscle interstitial prostaglandin E(2)(PGE(2)), prostacyclin I(2)(PGI(2)) and thromboxane A(2)(TXA(2)) levels during incremental dynamic exercise in humans determined by in vivo microdialysis. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418021
Norio K et al. Eicosanoids and delayed graft function in human renal transplantation. 2001 Transplant. Proc. pmid:11406239
Sontag W Release of mediators by DMSO-differentiated HL-60 cells exposed to electric interferential current and the requirement of biochemical prestimulation. 2001 Int. J. Radiat. Biol. pmid:11403712
Tuppo EE et al. Sign of lipid peroxidation as measured in the urine of patients with probable Alzheimer's disease. 2001 Brain Res. Bull. pmid:11397549
Cantaro S et al. Urinary excretion of vasoactive substances in chronic renal failure. 2001 Clin. Nephrol. pmid:11393385
Miyake K et al. Effects of olopatadine hydrochloride on the increase of histamine and peptide-leukotrienes concentrations in nasal lavage fluid following the antigen-antibody reaction in actively sensitized guinea pigs. 2001 Jpn. J. Pharmacol. pmid:11388650
Katoh M et al. Inhibitory effects of TA-993 and its metabolite MB3 on platelet activation induced by collagen and U-46619 in human platelets. 2001 Biol. Pharm. Bull. pmid:11379769
Ogata K et al. Attenuation of ischemia and reperfusion injury of canine livers by inhibition of type II phospholipase A2 with LY329722. 2001 Transplantation pmid:11374398
Yoshinari D et al. Effects of a dual inhibitor of tumor necrosis factor-alpha and interleukin-1 on lipopolysaccharide-induced lung injury in rats: involvement of the p38 mitogen-activated protein kinase pathway. 2001 Crit. Care Med. pmid:11373433
Loew D et al. Investigations on the pharmacokinetic properties of Harpagophytum extracts and their effects on eicosanoid biosynthesis in vitro and ex vivo. 2001 Clin. Pharmacol. Ther. pmid:11372004
Franconi F et al. Effect of gamma-hydroxybutyric acid on human platelet aggregation in vitro. 2001 Thromb. Res. pmid:11369419
Yu Y et al. [Changes of prostaglandins in kidney tissue in gentamicin-induced acute renal tubular injury in rats]. 1998 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:11367732
Zhang T et al. [Clinical observation on preventing and treating coronary atherosclerotic heart disease with tongmai jiangzhi oral liquid]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11367649
Wang LL et al. Effects of MN-9202 on platelet aggregation, 5-HT release, TXB2 synthesis, and calcium mobilization in rabbit platelets in vitro. 2000 Acta Pharmacol. Sin. pmid:11360670
Burch RM et al. Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of imidazole. 1979 J. Pharmacol. Exp. Ther. pmid:113526
Cracowski JL et al. Enhanced in vivo lipid peroxidation in scleroderma spectrum disorders. 2001 Arthritis Rheum. pmid:11352247
Karamouzis M et al. In situ microdialysis of intramuscular prostaglandin and thromboxane in contracting skeletal muscle in humans. 2001 Acta Physiol. Scand. pmid:11350265
Kijima Y et al. Transcardiac 8-iso-prostaglandin F(2 alpha)generation from acute myocardial infarction heart: insight into abrupt reperfusion and oxidant stress. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11334551