Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Edema, Cardiac D004489 1 associated lipids
Radiculopathy D011843 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Mitchell MD et al. Thromboxane B-2 in the plasma and amniotic fluid of late pregnant and periparturient sheep. 1979 J. Reprod. Fertil. pmid:423152
Tobelem G et al. Further studies on a specific platelet antibody found in Bernard-Soulier syndrome and its effects on normal platelet function. 1979 Br. J. Haematol. pmid:427045
Friedman LS et al. Cardiovascular and pulmonary effects of thromboxane B2 in the dog. 1979 Circ. Res. pmid:428069
Ciabattoni G et al. Characterization of furosemide-induced activation of the renal prostaglandin system. 1979 Eur. J. Pharmacol. pmid:393525
Svensson J Structure and quantitative determination of the major urinary metabolite of thromboxane B2 in the guinea pig. 1979 Prostaglandins pmid:472333
Langs DA et al. Thromboxane molecules do not adopt the prostaglandin hairpin conformation. 1979 Nature pmid:481594
Russell NH et al. Thrombocytopathy in preleukaemia: association with a defect of thromboxane A2 activity. 1979 Br. J. Haematol. pmid:570847
Anhut H et al. Prostaglandin D2 is the prevailing prostaglandin in the acute inflammatory exudate of urate arthritis in the chicken. 1979 Br. J. Pharmacol. pmid:570865
Lewy RI et al. Detection of thromboxane B2 in peripheral blood of patients with Prinzmetal's angina. 1979 Prostaglandins Med pmid:575861
Ohuchi K et al. Prostaglandins E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 levels in carrageenin-induced inflammatory exudates in the rat air-pouch granuloma. 1979 Prostaglandins Med pmid:583576
Davis TM et al. Prostacyclin and thromboxane metabolites in diabetes. 1979 Lancet pmid:90875
Best L et al. Effect of glucose on platelet thromboxane biosynthesis. 1979 Lancet pmid:90876
Jarabak J and Fried J Comparison of substrate specificities of the human placental NAD- and NADP-linked 15-hydroxyprostaglandin dehydrogenases. 1979 Prostaglandins pmid:42948
Miura Y and Fukui N Prostaglandins as possible triggers for liver regeneration after partial hepatectomy. A review. 1979 Cell Mol Biol Incl Cyto Enzymol pmid:44483
Karmazyn M and Dhalla NS Thromboxane B2: a cardiodepressant of isolated rat hearts and inhibitor of sarcolemma Na+ - K+ stimulated ATPase activity. 1979 Prostaglandins Med pmid:233217
Hassid A et al. Prostaglandin synthesis in isolated rat kidney glomeruli. 1979 Proc. Natl. Acad. Sci. U.S.A. pmid:286300
Le Breton GC et al. 13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor. 1979 Proc. Natl. Acad. Sci. U.S.A. pmid:291066
Chignard M et al. Arachidonate-mediated bronchoconstriction and platelet activation are inhibited by microgram doses of compound L8027 which are not selective for thromboxane synthetase. 1979 Agents Actions Suppl. pmid:291306
Peskar BA and Holland A Plasma levels of immunoreactive 15-keto-13,14-dihydro-thromboxane B2 in guinea pigs during anaphylaxis and after histamine injection. 1979 Agents Actions Suppl. pmid:294148
Anhut H et al. Thromboxane B2 release and 3H-noradrenaline accumulation by a synaptosomal fraction of rat brain. 1979 Jul-Aug Pol J Pharmacol Pharm pmid:523340
Pradalier A et al. [Measurement of plasma and serum values of PGE2, PGF2 alpha and TXB2 during aspirin induced bronchospasm in asthmatics (author's transl)]. 1979 Jul-Aug Therapie pmid:531778
Hagen AA et al. Synthesis of prostaglandins and thromboxane B2 by cerebral arteries. 1979 May-Jun Stroke pmid:462519
Olund A et al. Prostaglandins and thromboxanes in amniotic fluid during rivanol-induced abortion and labour. 1980 Prostaglandins pmid:6775353
Bisordi JE et al. Interaction of vasopressin and prostaglandins in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777397
Burch RM and Halushka PV Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777398
Galli C et al. Dietary essential fatty acids, tissue fatty acids and prostaglandin synthesis. 1980 Prog Food Nutr Sci pmid:6779348
Best LC et al. Studies on the role of calcium in the control of thromboxane B2 production. 1980 Artery pmid:6783015
Gullner HG et al. Correction of increased prostacyclin synthesis in Bartter's syndrome by indomethacin treatment. 1980 Prostaglandins Med pmid:6994153
Brodie MJ et al. Is prostacyclin in the major pro-inflammatory prostanoid in joint fluid? 1980 Life Sci. pmid:6999274
Silver MJ et al. A model system for studying initial events in atherosclerosis. 1980 Artery pmid:7000044
Fitzpatrick TM et al. Tromboxane B2 inhibits the pulmonary inactivation of prostaglandin E2 in the dog. 1980 Br. J. Pharmacol. pmid:7000216
Poyser NL and Scott FM Prostaglandin and thromboxane production by the rat uterus and ovary in vitro during the oestrous cycle. 1980 J. Reprod. Fertil. pmid:7001011
Lands WE et al. Recent concepts on platelet function and dietary lipids in coronary thrombosis, vasospasm and angina. 1980 Herz pmid:7007191
Subbiah MT et al. Enhancement of thrombocyte aggregation and thromboxane B2 synthesis by diethylstilbestrol. 1980 Pharmacology pmid:7220591
Harris RH et al. Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. 1980 Adv Prostaglandin Thromboxane Res pmid:6768234
Jécsai G and Bagdány S Quantitative determination of thromboxane synthesis in blood samples by video-densitometry. 1980 Acta Biochim. Biophys. Acad. Sci. Hung. pmid:7282294
Hwang DH Aggregation and inhibition of rat platelets, and the formation of endoperoxide metabolites. 1980 Prostaglandins Med pmid:7413850
Karmali RA et al. Intrarenal growth of the Walker 256 tumour and renal vein concentrations of PGE2, PGF 2 alpha, and TXB2: effects of diazepam. 1980 Prostaglandins Med pmid:7394064
Cooper JD et al. Prostaglandin production associated with the pulmonary vascular response to complement activation. 1980 Surgery pmid:7394704
Dupont J et al. Effects of dietary essential fatty acid concentration upon prostanoid synthesis in rats. 1980 J. Nutr. pmid:7400858
Rao GH et al. Influence of epinephrine on the aggregation response of aspirin-treated platelets. 1980 Prostaglandins Med pmid:7403340
Schrör K et al. Preservation of ischemic myocardium by pinane thromboxane A2. 1980 Am. J. Physiol. pmid:7356037
Hassid A and Dunn MJ Microsomal prostaglandin biosynthesis of human kidney. 1980 J. Biol. Chem. pmid:7358683
Kadowitz PJ and Hyman AL Comparative effects of thromboxane B2 on the canine and feline pulmonary vascular bed. 1980 J. Pharmacol. Exp. Ther. pmid:7365689
Stuart MJ et al. Effect of cholesterol on production of thromboxane b2 by platelets in vitro. 1980 N. Engl. J. Med. pmid:7350406
Wise WC et al. Ibuprofen improves survival from endotoxic shock in the rat. 1980 J. Pharmacol. Exp. Ther. pmid:7452480
Subbiah MT et al. Studies of aggregation and thromboxane B2 synthesis in avian thrombocytes: comparison between atherosclerosis-susceptible and resistant breeds. 1980 Thromb. Haemost. pmid:7455983
Pace-Asciak CR and Edwards NS Tetranor thromboxane B2 is the principal urinary catabolite formed after i.v. infusion of thromboxane B2 in the rat. 1980 Biochem. Biophys. Res. Commun. pmid:7458943
Viinikka L and Ylikorkala O Measurement of thromboxane B2 in human plasma or serum by radioimmunoassay. 1980 Prostaglandins pmid:7465865
Lagarde M et al. Increase of platelet thromboxane A2 formation and of its plasmatic half-life in diabetes mellitus. 1980 Thromb. Res. pmid:7466751