Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Erythromelalgia D004916 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Bluetongue D001819 1 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
Foot Rot D005535 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Nanji AA et al. Thromboxane inhibitors attenuate pathological changes in alcoholic liver disease in the rat. 1997 Gastroenterology pmid:8978360
Mathieu P et al. [Antiaggregant effect and tolerance of calcium carbasalate administrated immediately after aorto-coronary bypass. Results of a double-blind versus placebo study]. 1996 Pathol. Biol. pmid:8977914
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Landoni MF and Lees P Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in the horse. 1996 J. Vet. Pharmacol. Ther. pmid:8971676
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Fukushima C et al. Inhibitory effect of thromboxane A2 synthetase inhibitor, DP-1904, on antigen-induced contraction of human lung parenchyma. 1996 Ann. Allergy Asthma Immunol. pmid:8970439
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Krämer HJ et al. Fish oil fatty acids and human platelets: dose-dependent decrease in dienoic and increase in trienoic thromboxane generation. 1996 Biochem. Pharmacol. pmid:8937428
Klosterhalfen B et al. Influence of heat shock protein 70 and metallothionein induction by zinc-bis-(DL-hydrogenaspartate) on the release of inflammatory mediators in a porcine model of recurrent endotoxemia. 1996 Biochem. Pharmacol. pmid:8937427
Janssen PL et al. Consumption of ginger (Zingiber officinale roscoe) does not affect ex vivo platelet thromboxane production in humans. 1996 Eur J Clin Nutr pmid:8933126
Cirino G et al. Indomethacin and thromboxane A2/prostaglandin H2 antagonist SQ29,548 impair in vitro contractions of aortic rings of ex vivo-treated lipopolysaccharide rats. 1996 J Lipid Mediat Cell Signal pmid:8925198
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Serebruany VL et al. Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine. 1996 Pharmacology pmid:8902873
Livingston ER et al. Increased activation of the coagulation and fibrinolytic systems leads to hemorrhagic complications during left ventricular assist implantation. 1996 Circulation pmid:8901751
Karck U et al. PGE2 and PGF2 alpha release by human peritoneal macrophages in endometriosis. 1996 Prostaglandins pmid:8900443
Harada Y et al. Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy. 1996 Prostaglandins pmid:8900441
Chou TC et al. The inhibitory effect of 2-thienyl 2'-hydroxyphenyl ketone (C85) on platelet thromboxane formation. 1996 Thromb. Res. pmid:8897698
Myers SI et al. Estrogen increases male rat aortic endothelial cell (RAEC) PGI2 release. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8888351
Stiris TA et al. Effects of dexamethasone on retinal and choroidal blood flow during normoxia and hyperoxia in newborn piglets. 1996 Pediatr. Res. pmid:8888288
Carbajal D et al. Possible cytoprotective mechanism in rats of D-002, an anti-ulcerogenic product isolated from beeswax. 1996 J. Pharm. Pharmacol. pmid:8887738
García-Lafuente A et al. Bacterial peptides enhance inflammatory activity in a rat model of colitis. 1996 Digestion pmid:8886582
Ziyyat A et al. Interactions between nitric oxide and prostanoids in isolated perfused kidneys of the rat. 1996 Br. J. Pharmacol. pmid:8886425
Selley ML et al. The effect of cholesterol oxidation products on human platelet aggregation. 1996 Thromb. Res. pmid:8885139
Mustad V et al. Seasonal variation in parameters related to coronary heart disease risk in young men. 1996 Atherosclerosis pmid:8879440
Schaefer WR et al. Urinary excretion of 2,3-dinor-6-keto-PGF1 alpha and 11-dehydro-TXB2 by the gravid spontaneously hypertensive rat. 1996 Prostaglandins pmid:8875634
Siler-Khodr TM et al. Dose-related action of estradiol on placental prostanoid prediction. 1996 Prostaglandins pmid:8873234
Kanai H et al. Serotonin metabolism in patients undergoing hemodialysis. 1996 Clin. Nephrol. pmid:8861800
Pancera P et al. Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8860111
Bordia T et al. An evaluation of garlic and onion as antithrombotic agents. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8860105
Reale M et al. Human recombinant interleukin-1 beta induces thromboxane A2 release in polymorphonuclear leukocytes, macrophages and platelets: effect of IL-1 receptor antagonist. 1996 Mol. Cell. Biochem. pmid:8858567
Quinn JV et al. Evaluation of enzyme-linked immunosorbent assays for quantitation of eicosanoid mediators of sepsis syndrome. 1996 Shock pmid:8856849
Chen SJ et al. Antiplatelet and calcium inhibitory properties of eugenol and sodium eugenol acetate. 1996 Gen. Pharmacol. pmid:8853295
Gabriel A et al. Influence of prostaglandin E1 on tissue ischemia during surgical repair of the abdominal aorta. 1996 J. Cardiothorac. Vasc. Anesth. pmid:8850397
Horiguchi T et al. Pulmonary responses to heparin-protamine complexes: the effects of age and species. 1996 J. Appl. Physiol. pmid:8847332