Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Acute Kidney Injury D058186 34 associated lipids
Airway Remodeling D056151 3 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Atherosclerosis D050197 85 associated lipids
Dyslipidemias D050171 7 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Coronary Stenosis D023921 6 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Kangasaho M et al. Formation of thromboxane B2 by platelets and concentrations of thromboxane B2 and 6-keto-prostaglandin F1 alpha in plasma after acute ethanol ingestion. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6303086
Foegh ML et al. Eicosanoids, gamma-interferon and inflammatory cells in kidney transplant patients. 1986 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2949550
Granström E and Kumlin M Assay of thromboxane production in biological systems: reliability of TXB2 versus 11-dehydro-TXB2 as targets for measurement. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960161
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Müller M In vivo measurement of interstitial TxB2-concentrations in skeletal muscle during ischemia and reperfusion. 1997 Adv. Exp. Med. Biol. pmid:9561122
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Moncada S and Whittle BJ Biological actions of prostacyclin and its pharmacological use in platelet studies. 1985 Adv. Exp. Med. Biol. pmid:3010671
Bourgeois N et al. Effects of endotoxin on hemodynamics of isolated dog kidney. 1987 Adv. Exp. Med. Biol. pmid:3303858
Flynn JT and Demling RH Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. 1982 Adv Shock Res pmid:6753534
Lefer AM and Crossley K Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia. 1980 Adv Shock Res pmid:7304314
Zamecnik J et al. Concentrations of thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid, decidual tissue, and placenta in the later stages of pregnancy in the rat. 1980 Adv Prostaglandin Thromboxane Res pmid:6990719
Frame MH et al. Inhibition of acid secretion from the rat-isolated gastric mucosa by arachidonic acid and identification of major metabolites. 1980 Adv Prostaglandin Thromboxane Res pmid:6990724
Sanger GJ and Bennett A Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. 1980 Adv Prostaglandin Thromboxane Res pmid:6103666
Harris RH et al. Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. 1980 Adv Prostaglandin Thromboxane Res pmid:6768234
Güllner HG et al. The principal metabolites of arachidonic acid are overproduced in Bartter's syndrome. 1980 Adv Prostaglandin Thromboxane Res pmid:6892749
Schlondorff D and Folkert VW Prostaglandin synthesis in glomeruli from rats with unilateral ureteral obstruction. 1980 Adv Prostaglandin Thromboxane Res pmid:7369028
Lindgren JA et al. Effects of platelet aggregation and adenosine 3':5'-monophosphate on the synthesis of thromboxane B2 in human platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:6247886
Gorman RR Biochemical and pharmacological evaluation of thromboxane synthetase inhibitors. 1980 Adv Prostaglandin Thromboxane Res pmid:6247892
Friedman LS et al. Thromboxane B2 inhibits the pulmonary metabolism of PGE2 in the anesthetized dog. 1980 Adv Prostaglandin Thromboxane Res pmid:7369063
Bishai I and Coceani F Metabolism of PGH2 in the feline brain. 1980 Adv Prostaglandin Thromboxane Res pmid:7376980
Galli C et al. Factors affecting brain prostaglandin formation. 1980 Adv Prostaglandin Thromboxane Res pmid:7376983
Blotman F et al. PGE2, PGF2 alpha, and TXB2 biosynthesis by human rheumatoid synovia. 1980 Adv Prostaglandin Thromboxane Res pmid:7377017
Katori M et al. Changes of prostaglandin and thromboxane levels in pleural fluid of rat carrageenin-induced pleurisy. 1980 Adv Prostaglandin Thromboxane Res pmid:7377020
Crutchley DJ et al. Potentiation of thromboxane B2 release from guinea pig lung during anaphylaxis following exposure to 100% O2. 1980 Adv Prostaglandin Thromboxane Res pmid:7377022
Morris HG and Sherman NA Prostaglandin-like substances in urine of asthmatic patients. 1980 Adv Prostaglandin Thromboxane Res pmid:7377024
Schoene NW et al. Effects of diets varying in fat and P/S ratio on arachidonic acid metabolism in human platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:7377026
Patrono C et al. Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function. 1980 Adv Prostaglandin Thromboxane Res pmid:7386257
Langs DA et al. Thromboxane molecules are not hairpin conformers. 1980 Adv Prostaglandin Thromboxane Res pmid:7386281
Bailey JM Essential fatty acid requirements and metabolism of cells in tissue culture. 1980 Adv Prostaglandin Thromboxane Res pmid:7386288
Feinstein MB et al. Serine-esterase (protease) inhibitors block stimulus-induced mobilization of arachidonate in platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:6770602