Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Arakawa K et al. Bradykinin B2 receptor antagonist FR173657 ameliorates small bowel ischemia-reperfusion injury in dogs. 2005 Dig. Dis. Sci. pmid:15712633
Pampolina C and McNicol A Streptococcus sanguis-induced platelet activation involves two waves of tyrosine phosphorylation mediated by FcgammaRIIA and alphaIIbbeta3. 2005 Thromb. Haemost. pmid:15886812
Ikonomidis I et al. Cigarette smoking is associated with increased circulating proinflammatory and procoagulant markers in patients with chronic coronary artery disease: effects of aspirin treatment. 2005 Am. Heart J. pmid:15894964
Petrikova M et al. Carvedilol--a beta-blocker with considerable antiaggregatory effect on human blood platelets. 2005 Bratisl Lek Listy pmid:15869009
Komers R et al. Renal cyclooxygenase-2 in obese Zucker (fatty) rats. 2005 Kidney Int. pmid:15882258
Chang P et al. Therapeutic effects and possible mechanisms of a snake venom preparation in the fibrotic rat liver. 2005 Dig. Dis. Sci. pmid:15844712
Bowen RS et al. Increased phospholipase A2 and thromboxane but not prostacyclin production by placental trophoblast cells from normal and preeclamptic pregnancies cultured under hypoxia condition. 2005 Placenta pmid:15850645
Myers SI et al. Bile duct ligation induced acute inflammation up-regulates cyclooxygenase-2 content and PGE2 release in guinea pig gallbladder smooth muscle cell cultures. 2005 Prostaglandins Leukot. Essent. Fatty Acids pmid:15850713
Nakamura K et al. Influence of preoperative administration of omega-3 fatty acid-enriched supplement on inflammatory and immune responses in patients undergoing major surgery for cancer. 2005 Nutrition pmid:15925286
Coppola A et al. Reduced in vivo oxidative stress following 5-methyltetrahydrofolate supplementation in patients with early-onset thrombosis and 677TT methylenetetrahydrofolate reductase genotype. 2005 Br. J. Haematol. pmid:16173969
Blume C et al. Different effect of cyclosporine A and mycophenolate mofetil on passive Heymann nephritis in the rat. 2005 Nephron Exp. Nephrol. pmid:15855806
Giraudel JM et al. Development of in vitro assays for the evaluation of cyclooxygenase inhibitors and predicting selectivity of nonsteroidal anti-inflammatory drugs in cats. 2005 Am. J. Vet. Res. pmid:15900953
Wu CC et al. 2-(2-Br-phenyl)-8-methoxy-benzoxazinone (HPW-RX2), a direct thrombin inhibitor with a suppressive effect on thromboxane formation in platelets. 2005 Eur. J. Pharmacol. pmid:16313903
Visioli F et al. Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients. 2005 Eur J Nutr pmid:15309433
Jin YR et al. Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ mobilization. 2005 J. Pharmacol. Exp. Ther. pmid:15328379
Zhu S et al. [Influence of Minkeqing oral liquid on IL-6, IL-8, ET-1, TX-B2 in blood and to observe bronchoalveolar lavage fluid of the rat with inhalating ovalbumin]. 2005 Zhongguo Zhong Yao Za Zhi pmid:16161448
Corazzi T et al. Direct and irreversible inhibition of cyclooxygenase-1 by nitroaspirin (NCX 4016). 2005 J. Pharmacol. Exp. Ther. pmid:16144976
Haubelt H et al. Can platelet function tests predict the clinical efficacy of aspirin? 2005 Semin. Thromb. Hemost. pmid:16149017
Cao D et al. Chronic administration of ethyl docosahexaenoate decreases mortality and cerebral edema in ischemic gerbils. 2005 Life Sci. pmid:16214179
Sciulli MG et al. Platelet activation in patients with colorectal cancer. 2005 Prostaglandins Leukot. Essent. Fatty Acids pmid:15626589
Gonzalez-Conejero R et al. Biological assessment of aspirin efficacy on healthy individuals: heterogeneous response or aspirin failure? 2005 Stroke pmid:15604423
Zheng YN et al. Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism. 2005 Yakugaku Zasshi pmid:16327246
Yugar-Toledo JC et al. Blood pressure circadian rhythm and endothelial function in heavy smokers: acute effects of transdermal nicotine. 2005 J Clin Hypertens (Greenwich) pmid:16330894
Yao X et al. [The changes of some vasoactive substances after operation in patients with obstructive sleep apnea-hypopnea syndrome]. 2005 Lin Chuang Er Bi Yan Hou Ke Za Zhi pmid:16398051
Kong XY and Gong PL [Effect of phenolic alkaloids of Menispermum dauricum on thrombosis and platelet aggregation]. 2005 Yao Xue Xue Bao pmid:16408809
de Sotomayor MA et al. Improvement of age-related endothelial dysfunction by simvastatin: effect on NO and COX pathways. 2005 Br. J. Pharmacol. pmid:16231003
Daza L et al. Captopril effect on prostaglandin E2, thromboxane B2 and proteinuria in lupus nephritis patients. 2005 Prostaglandins Other Lipid Mediat. pmid:16303616
Mason PJ et al. Plasma, serum, and platelet expression of CD40 ligand in adults with cardiovascular disease. 2005 Am. J. Cardiol. pmid:16275179
Phillips J and Pearce B Serum deprivation and re-addition: effects on cyclooxygenase inhibitor sensitivity in cultured glia. 2005 Inflammopharmacology pmid:16280096
Gambero A et al. Comparative study of anti-inflammatory and ulcerogenic activities of different cyclo-oxygenase inhibitors. 2005 Inflammopharmacology pmid:16280097
Chang Y et al. Mechanisms involved in the antiplatelet activity of ketamine in human platelets. 2004 Nov-Dec J. Biomed. Sci. pmid:15591773
Barrière G et al. PHGPx overexpression induces an increase in COX-2 activity in colon carcinoma cells. 2004 May-Jun Anticancer Res. pmid:15274299
Moriguchi A et al. Antithrombotic effects of FK419, a novel nonpeptide platelet GPIIb/IIIa antagonist, in a guinea pig photochemically induced middle cerebral artery thrombosis model: comparison with ozagrel and argatroban. 2004 J. Pharmacol. Exp. Ther. pmid:14634048
Kojima F et al. Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis. 2004 Arthritis Res. Ther. pmid:15225371
Farndale RW et al. Measurement of platelet arachidonic acid metabolism. 2004 Methods Mol. Biol. pmid:15226540
Barbara J et al. Inhaled cornstarch glove powder increases latex-induced airway hyper-sensitivity in guinea-pigs. 2004 Clin. Exp. Allergy pmid:15196289
Wu KJ et al. [Detection of thromboxane B2, 6-keto-prostaglandin F1alpha and anticardiolipin antibody in patients with obstructive sleep apnea-hypopnea syndrome]. 2004 Zhonghua Jie He He Hu Xi Za Zhi pmid:15196341
Van Ryn J et al. Meloxicam does not affect the antiplatelet effect of aspirin in healthy male and female volunteers. 2004 J Clin Pharmacol pmid:15199082
Aikawa K et al. Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs. 2004 Coron. Artery Dis. pmid:15201617
Lorenzoni R et al. Short-term prevention of thromboembolic complications in patients with atrial fibrillation with aspirin plus clopidogrel: the Clopidogrel-Aspirin Atrial Fibrillation (CLAAF) pilot study. 2004 Am. Heart J. pmid:15215815
Zhang L et al. Effects of thiol antioxidant on reduced nicotinamide adenine dinucleotide phosphate oxidase in hypertensive Dahl salt-sensitive rats. 2004 Free Radic. Biol. Med. pmid:15528040
Park WH et al. Anti-inflammatory effects of a traditional Korean herbal formulation, Silsosangami, consisting of seven medicinal herbs: effect on hemolysis, neutrophil function, and gene expressions of iNOS and COX-2. 2004 Vascul. Pharmacol. pmid:15664882
Vainio M et al. Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders. 2004 Acta Obstet Gynecol Scand pmid:15548142
Tsai CY et al. Proinflammatory cytokines enhance COX-1 gene expression in cultured rat glomerular mesangial cells. 2004 Int. Immunopharmacol. pmid:14975359
Smalling WE et al. Protective effect of pentoxifylline on volume-induced lung injury in newborn piglets. 2004 Biol. Neonate pmid:14981352
Ikonomidis I et al. Reduction of daily life ischaemia by aspirin in patients with angina: underlying link between thromboxane A2 and macrophage colony stimulating factor. 2004 Heart pmid:15020512
Dippel DW et al. What is the lowest dose of aspirin for maximum suppression of in vivo thromboxane production after a transient ischemic attack or ischemic stroke? 2004 Cerebrovasc. Dis. pmid:15026612
Horani MH et al. Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2. 2004 Metab. Clin. Exp. pmid:14767868
Kawada N et al. TP receptors regulate renal hemodynamics during angiotensin II slow pressor response. 2004 Am. J. Physiol. Renal Physiol. pmid:15213069
Peck OM et al. Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: role of interferon-gamma. 2004 Shock pmid:14770039