Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Radiculopathy D011843 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Bluetongue D001819 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Edema, Cardiac D004489 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Heart Septal Defects D006343 2 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Weil Disease D014895 2 associated lipids
Drowning D004332 2 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Infertility D007246 3 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Macular Edema D008269 3 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Yang Deficiency D016711 3 associated lipids
Contusions D003288 3 associated lipids
Bronchopulmonary Sequestration D001998 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Jejunal Diseases D007579 3 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Retinal Diseases D012164 4 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Menorrhagia D008595 4 associated lipids
Thrombasthenia D013915 4 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Diseases in Twins D004200 4 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Facial Pain D005157 5 associated lipids
Bartter Syndrome D001477 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Mastocytosis D008415 5 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypercapnia D006935 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Asthenia D001247 5 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Sclerosis D012598 5 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
beta-Thalassemia D017086 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Placenta Diseases D010922 5 associated lipids
Thrombophilia D019851 6 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Sneezing D012912 6 associated lipids
Coronary Stenosis D023921 6 associated lipids
Thromboembolism D013923 6 associated lipids
Bronchitis D001991 6 associated lipids
Intermittent Claudication D007383 6 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Tachycardia D013610 7 associated lipids
Dyslipidemias D050171 7 associated lipids
Keratitis D007634 7 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Varicose Veins D014648 7 associated lipids
Behcet Syndrome D001528 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Agranulocytosis D000380 7 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Lupus Nephritis D008181 8 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Sheehan DV et al. Some biochemical correlates of panic attacks with agoraphobia and their response to a new treatment. 1984 J Clin Psychopharmacol pmid:6142907
Barnett AH et al. Specific thromboxane synthetase inhibition and albumin excretion rate in insulin-dependent diabetes. 1984 Lancet pmid:6145027
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Schwartz D et al. Renal arachidonic acid metabolism and cellular changes in the rabbit renal vein constricted kidney: inflammation as a common process in renal injury models. 1984 Prostaglandins pmid:6427853
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Benedetto C et al. Production of prostacyclin, 6-keto-PGF1 alpha and thromboxane B2 by incubated samples of umbilical vessels: a comparison of methods for expressing the results on dry weight, wet weight, protein or DNA bases. 1984 Prostaglandins pmid:6390522
FitzGerald GA and Oates JA Selective and nonselective inhibition of thromboxane formation. 1984 Clin. Pharmacol. Ther. pmid:6370554
Welton AF et al. Ro 22-3747: a new antiallergic agent for the treatment of immediate hypersensitivity diseases. 1984 J. Pharmacol. Exp. Ther. pmid:6198511
Navran SS et al. Human platelet activation by bacterial phospholipase C is mediated by phosphatidylinositol hydrolysis but not generation of phosphatidic acid: inhibition by a selective inhibitor of phospholipase C. 1984 Thromb. Res. pmid:6372157
Furman BL et al. Failure of drugs that selectively inhibit thromboxane synthesis to modify endotoxin shock in conscious rats. 1984 Br. J. Pharmacol. pmid:6375795
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Carter AJ et al. A comparison of human pulmonary arterial and venous prostacyclin and thromboxane synthesis--effect of a thromboxane synthase inhibitor. 1984 Thromb. Haemost. pmid:6377567
Fitzpatrick F et al. Development of a gas chromatographic-mass spectrometric method using a stable isotope internal standard for quantitation of thromboxane B2. 1984 Thromb. Res. pmid:6474413
Salvetti A et al. The influence of indomethacin and sulindac on some pharmacological actions of atenolol in hypertensive patients. 1984 Br J Clin Pharmacol pmid:6378233
Watanabe J et al. Effect of vitamin E on platelet aggregation in diabetes mellitus. 1984 Tohoku J. Exp. Med. pmid:6474447
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Wilson L and Huang LS Temporal response of uterine prostaglandins to estradiol treatment in the ovariectomized-pregnant rat. 1984 Prostaglandins pmid:6484214
Walinsky P et al. Thromboxane A2 in acute myocardial infarction. 1984 Am. Heart J. pmid:6485997
Ishii H et al. The effect of plasma on platelet function in hypercholesterolemic rabbits and the changes in fatty acid composition of the plasma. 1984 Thromb. Res. pmid:6234679
D'Angelo A et al. Increased production of platelet thromboxane B2 in non-insulin-dependent diabetes. Relationship to vascular complications. 1984 Eur. J. Clin. Invest. pmid:6428908
Del Maschio A et al. Inhibition of human platelet cyclo-oxygenase activity by sulfinpyrazone and three of its metabolites. 1984 Eur. J. Pharmacol. pmid:6432556
Schenkein HA and Rutherford RB Effects of serum on C3b-stimulated release of prostaglandins and thromboxane B2 from human monocytes. 1984 Immunopharmacology pmid:6511367
Fung WP et al. Effect of ethanol on gastric secretion of thromboxane B2. 1984 Med. J. Malaysia pmid:6513851
Watanabe J et al. Effect of prostaglandin synthetase inhibitors on platelet aggregation and thromboxane production in diabetes mellitus. 1984 Tohoku J. Exp. Med. pmid:6515648
Ditter H and Matthias FR Changes in thromboxane formation by platelets during and after a continuous endotoxin infusion into rabbits. 1984 VASA pmid:6516562
Uotila P et al. Prostanoids and hemodynamics in man before and during cardiopulmonary bypass. 1984 Prostaglandins pmid:6335260
Hänsch GM et al. Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components. 1984 J. Immunol. pmid:6432907
Rachmilewitz D and Karmeli F Effect of nufenoxole on human colonic prostanoid synthesis, Na-K-ATPase and adenylate cyclase activities. 1984 Eur. J. Pharmacol. pmid:6152213
De Caterina R et al. Inhibition of platelet function by injectable isosorbide dinitrate. 1984 Am. J. Cardiol. pmid:6428211
Stock JL and Coderre JA Calcitonin enhances production of prostaglandins by stimulated human monocytes. 1984 Prostaglandins pmid:6087420
Triolo G et al. Circulating immune complexes and platelet thromboxane synthesis in patients with insulin-dependent (type I) diabetes mellitus. 1984 Diabetes pmid:6611280
Yui Y et al. Intravenous infusion of a selective inhibitor of thromboxane A2 synthetase in man: influence on thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and platelet aggregation. 1984 Circulation pmid:6434196
Koike K et al. Platelet secretion defect in patients with the attention deficit disorder and easy bruising. 1984 Blood pmid:6692042
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Jackson CA et al. Near-normal glycaemic control does not correct abnormal platelet reactivity in diabetes mellitus. 1984 Clin. Sci. pmid:6434224
Vesterqvist O et al. Development of a GC-MS method for quantitation of 2,3-dinor-TxB2 and determinations of the daily urinary excretion rates in healthy humans. 1984 Thromb. Res. pmid:6695361
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Mehta J et al. Thromboxane release in coronary artery disease: spontaneous versus pacing-induced angina. 1984 Am. Heart J. pmid:6695662
Klotz TA et al. Urinary excretion of thromboxane B2 in patients with venous thromboembolic disease. 1984 Chest pmid:6697787
Maddox Y et al. A routine source of human peritoneal macrophages. 1984 Scand. J. Immunol. pmid:6701470
Girotti MJ et al. Effects of immunization on cardiopulmonary alterations of gram-negative endotoxemia. 1984 J Appl Physiol Respir Environ Exerc Physiol pmid:6368499
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Ylikorkala O et al. Peritoneal fluid prostaglandins in endometriosis, tubal disorders, and unexplained infertility. 1984 Obstet Gynecol pmid:6232475
Simberg N Maternal aspirin administration inhibits pulmonary arachidonic acid metabolism in fetal rabbits. 1984 Prostaglandins Leukot Med pmid:6425868
Koskimies AI et al. Peritoneal fluid 6-keto-prostaglandin F1 alpha, thromboxane B2 in endometriosis and unexplained infertility. 1984 Acta Obstet Gynecol Scand Suppl pmid:6594012
Branski D et al. Prostaglandins in small intestinal mucosa of children with celiac disease. 1984 J. Pediatr. Gastroenterol. Nutr. pmid:6594493
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Ogushi F et al. [In vitro release of arachidonate metabolites by human alveolar macrophages]. 1984 Nihon Kyobu Shikkan Gakkai Zasshi pmid:6595434
Bommer J et al. Plastic filing from dialysis tubing induces prostanoid release from macrophages. 1984 Kidney Int. pmid:6595463
Brandt R et al. Effect of propranolol, practolol and atenolol on human platelet thromboxane formation and plasma levels of prostaglandins 6-keto-F1 alpha and E2. 1984 Prostaglandins Leukot Med pmid:6597450
Chiba S et al. Sex and age-related differences in the urinary excretion of TXB2 in normal human subjects: a possible pathophysiological role of TXA2 in the aged kidney. 1984 Prostaglandins Leukot Med pmid:6597456
Mahmud I et al. Thromboxane synthesizing system in rat liver. 1984 Prostaglandins Leukot Med pmid:6597457
Morrison AR and Crowley JR Identification of an unusual cyclooxygenase metabolite of arachidonic acid in rabbit renal medulla. 1984 Arch. Biochem. Biophys. pmid:6437329
Holgate ST et al. Anaphylactic- and calcium-dependent generation of prostaglandin D2 (PGD2), thromboxane B2, and other cyclooxygenase products of arachidonic acid by dispersed human lung cells and relationship to histamine release. 1984 J. Immunol. pmid:6206153
Stimler NP Spasmogenic activity of C5adesArg anaphylatoxin on guinea pig lung parenchymal strips: sensitivity of the leukotriene-mediated component to cyclooxygenase inhibitors. 1984 Biochem. Biophys. Res. Commun. pmid:6440564
Mallarkey G and Smith GM In vivo platelet aggregation in the rat: dependence on extracellular divalent cation and inhibition by nonsteroidal anti-inflammatory drugs. 1984 Br. J. Pharmacol. pmid:6423018
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Fuller RW et al. Dexamethasone inhibits the production of thromboxane B2 and leukotriene B4 by human alveolar and peritoneal macrophages in culture. 1984 Clin. Sci. pmid:6091982
Hall ER et al. The reduction of potential TXB2 levels when serum is preincubated at room temperature. 1984 Prostaglandins Leukot Med pmid:6585846
Coker SJ Further evidence that thromboxane exacerbates arrhythmias: effects of UK38485 during coronary artery occlusion and reperfusion in anaesthetized greyhounds. 1984 J. Mol. Cell. Cardiol. pmid:6433026
Codde JP et al. Validation of the direct radioimmunoassay of prostanoids in serum and kidney. 1984 Prostaglandins Leukot Med pmid:6587406
Shaala S et al. Local effect of thromboxane B2 on the contractility of the human non pregnant uterus. 1984 Prostaglandins Leukot Med pmid:6587408
Higgins AJ et al. Influence of phenylbutazone on eicosanoid levels in equine acute inflammatory exudate. 1984 Cornell Vet pmid:6587959
Krell RD and Kusner EJ Differential effect of cyclo-oxygenase inhibition on antigen- and ionophore-induced release of slow reacting substance from fragmented guinea-pig lung. 1984 Br. J. Pharmacol. pmid:6434013
Meydani M et al. Effects of dietary methionine, methylmercury, and atrazine on ex-vivo synthesis of prostaglandin E1 and thromboxane B2. 1984 Prostaglandins Leukot Med pmid:6588393
Branski D et al. Effect of cimetidine on human gastric and duodenal prostanoid synthesis. 1984 Scand. J. Gastroenterol. pmid:6589742
Galli C et al. Acute effects of ethanol, caffeine, or both on platelet aggregation, thromboxane formation, and plasma-free fatty acids in normal subjects. 1984 Drug Nutr Interact pmid:6510241
Lelcuk S et al. Inhibition of ischemia-induced thromboxane synthesis in man. 1984 J Trauma pmid:6325720
Swart SS et al. Functional significance of the platelet alpha2-adrenoceptor: studies in patients with myeloproliferative disorders. 1984 Thromb. Res. pmid:6326344
Turk J et al. Arachidonic acid metabolism in isolated pancreatic islets. I. Identification and quantitation of lipoxygenase and cyclooxygenase products. 1984 Biochim. Biophys. Acta pmid:6329307
Gal D et al. Effect of radiation on prostaglandin production by human bowel in vitro. 1984 Int. J. Radiat. Oncol. Biol. Phys. pmid:6588048
Oglesby TD and Gorman RR The inhibition of arachidonic acid metabolism in human platelets by RHC 80267, a diacylglycerol lipase inhibitor. 1984 Biochim. Biophys. Acta pmid:6424715