Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Eldor A et al. | A chronic hypercoagulable state in patients with beta-thalassaemia major is already present in childhood. | 1999 | Br. J. Haematol. | pmid:10606878 |
Reis F et al. | The peripheral serotonergic system and platelet aggregation in cyclosporin A-induced hypertensive rats. | 1999 | Thromb. Res. | pmid:10605951 |
De La Cruz JP et al. | Antiplatelet effect of the anaesthetic drug propofol: influence of red blood cells and leucocytes. | 1999 | Br. J. Pharmacol. | pmid:10602334 |
Chou TC and Li CY | Inhibitory mechanisms of dantrolene on platelet aggregation. | 1999 | Thromb. Res. | pmid:10593433 |
Kohda N et al. | Effect of cilostazol, a phosphodiesterase III inhibitor, on experimental thrombosis in the porcine carotid artery. | 1999 | Thromb. Res. | pmid:10593428 |
Hoch B and Bernhard M | Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10593170 |
Hishinuma T et al. | Urinary thromboxane A2/prostacyclin balance reflects the pathological state of a diabetic. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10593168 |
Mizugaki M et al. | Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10593167 |
Pavord ID et al. | Induced sputum eicosanoid concentrations in asthma. | 1999 | Am. J. Respir. Crit. Care Med. | pmid:10588604 |
Pirich C et al. | Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. | 1999 | Thromb. Res. | pmid:10588465 |
Gallery ED et al. | In vitro human decidual endothelial cell thromboxane secretion in preeclampsia is not abnormal. | 1999 | Hypertens Pregnancy | pmid:10586525 |
Vijaya Kumar M et al. | The anhydrous milk fat, ghee, lowers serum prostaglandins and secretion of leukotrienes by rat peritoneal macrophages. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10574649 |
Castellani S et al. | Impaired renal adaptation to stress in the elderly with isolated systolic hypertension. | 1999 | Hypertension | pmid:10567190 |
Titos E et al. | Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). | 1999 | Am. J. Physiol. | pmid:10564079 |
Heller A et al. | Pancreatitis-associated protein protects the lung from leukocyte-induced injury. | 1999 | Anesthesiology | pmid:10551593 |
Hirakata H et al. | Propofol has both enhancing and suppressing effects on human platelet aggregation in vitro. | 1999 | Anesthesiology | pmid:10551587 |
Nemcova S et al. | Cyclic nucleotides and production of prostanoids in human varicose veins. | 1999 | J. Vasc. Surg. | pmid:10550185 |
Reeves JH et al. | Continuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group. | 1999 | Crit. Care Med. | pmid:10548188 |
de Meijer A et al. | Meloxicam, 15 mg/day, spares platelet function in healthy volunteers. | 1999 | Clin. Pharmacol. Ther. | pmid:10546927 |
Pearl JM et al. | Effect of modified ultrafiltration on plasma thromboxane B2, leukotriene B4, and endothelin-1 in infants undergoing cardiopulmonary bypass. | 1999 | Ann. Thorac. Surg. | pmid:10543508 |
Chou TC et al. | Antiplatelet effect of amlodipine: a possible mechanism through a nitric oxide-mediated process. | 1999 | Biochem. Pharmacol. | pmid:10535758 |
Serebruany VL et al. | Effects of a novel Mac-1 inhibitor, NPC 15669, on hemostatic parameters during preconditioned myocardial infarction. | 1999 | Life Sci. | pmid:10530802 |
Véricel E et al. | The influence of low intake of n-3 fatty acids on platelets in elderly people. | 1999 | Atherosclerosis | pmid:10525140 |