Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Desquand S et al. | Interference of BN 52021, an antagonist of PAF, with different forms of active anaphylaxis in the guinea-pig: importance of the booster injection. | 1991 | Br. J. Pharmacol. | pmid:1285397 |
| Pettus BJ et al. | Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release. | 2003 | J. Biol. Chem. | pmid:12855693 |
| Miceli M et al. | Effect of low doses of ethanol on platelet function in long-life abstainers and moderate-wine drinkers. | 2003 | Life Sci. | pmid:12865095 |
| Heller AR et al. | Clusterin protects the lung from leukocyte-induced injury. | 2003 | Shock | pmid:12865662 |
| De Cristofaro R et al. | Lipid and protein oxidation contribute to a prothrombotic state in patients with type 2 diabetes mellitus. | 2003 | J. Thromb. Haemost. | pmid:12871497 |
| Wolfram R et al. | Daily prickly pear consumption improves platelet function. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12878452 |
| Villalobos MA et al. | Effects of camonagrel, a selective inhibitor of platelet thromboxane synthase, on the platelet-subendothelium interaction. | 2003 | Pharmacology | pmid:12886030 |
| Montalescot G et al. | Lack of platelet-activating factor release during reversible myocardial ischaemia. | 1992 | Eur. Heart J. | pmid:1289094 |
| Dapper F et al. | Effects of pulsatile and nonpulsatile perfusion mode during extracorporeal circulation--a comparative clinical study. | 1992 | Thorac Cardiovasc Surg | pmid:1290181 |
| Pestel S et al. | Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. | 2003 | Biochem. Pharmacol. | pmid:12906929 |
| Shimada N et al. | Increased endothelin: nitric oxide ratio is associated with erythropoietin-induced hypertension in hemodialysis patients. | 2003 | Ren Fail | pmid:12911161 |
| Patrono C | Aspirin resistance: definition, mechanisms and clinical read-outs. | 2003 | J. Thromb. Haemost. | pmid:12911581 |
| OuYang WX | [Mechanism and effect of anisodamine on uteroplacental circulation in pregnancy-induced hypertension]. | 1992 | Zhonghua Fu Chan Ke Za Zhi | pmid:1291219 |
| Tomita Y et al. | Melanocyte-stimulating properties of arachidonic acid metabolites: possible role in postinflammatory pigmentation. | 1992 | Pigment Cell Res. | pmid:1292020 |
| Jörres A et al. | Thromboxane B2 urinary metabolites in patients undergoing cardiopulmonary bypass. | 1992 | Eicosanoids | pmid:1292525 |
| Yu CC and Lai YL | Chronic hypoxia attenuates ischemia-reperfusion-induced increase in pulmonary vascular resistance. | 2003 | Life Sci. | pmid:12927588 |
| Zhuang HP et al. | [Effect of aspirin combined with perindopril on prostacyclin, thromboxone A2, and norepinephrine in the blood of arteriosclerosis rabbit models and the cardiac function]. | 2003 | Hunan Yi Ke Da Xue Xue Bao | pmid:12934393 |
| Al-Waili NS and Boni NS | Natural honey lowers plasma prostaglandin concentrations in normal individuals. | 2003 | J Med Food | pmid:12935324 |
| Tsipas G and Morphake P | Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. | 2003 | J. Nutr. Biochem. | pmid:12948879 |
| Wu X et al. | Zileuton, a 5-lipoxygenase inhibitor, increases production of thromboxane A2 and platelet aggregation in patients with asthma. | 2003 | Am. J. Hematol. | pmid:12949886 |
| Seebacher F and Franklin CE | Prostaglandins are important in thermoregulation of a reptile (Pogona vitticeps). | 2003 | Proc. Biol. Sci. | pmid:12952634 |
| Chen HI et al. | Effects of acute exercise on the biosynthesis of eicosanoids in rats. | 1992 | Chin J Physiol | pmid:1295717 |
| Tanigawa T et al. | Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: possible involvement of PGE2. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12958020 |
| Cerletti C et al. | Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes. | 2003 | Clin Pharmacokinet | pmid:12959636 |
| Dionne RA et al. | Dexamethasone suppresses peripheral prostanoid levels without analgesia in a clinical model of acute inflammation. | 2003 | J. Oral Maxillofac. Surg. | pmid:12966473 |
| Liu H et al. | Clinical implication of the changes of cAMP, TXA2 and PGI2 in CSF of asphyxiated newborns. | 2003 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:12973949 |
| Chantharaksri U et al. | Pathogenesis of hypoxemia. | 1992 | Southeast Asian J. Trop. Med. Public Health | pmid:1298990 |
| Bassalyk LS et al. | [The effect of indomethacin and leukinferon on the thromboxane B2 level in the blood plasma of patients with endometrial cancer in the perioperative period]. | 1992 | Vopr Onkol | pmid:1300754 |
| Jiang HW et al. | [Clinical study in treating qi-deficiency and blood-stasis syndrome of angina pectoris with qi xue granule]. | 1992 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:1301847 |
| Taylor BJ et al. | Effects of alveolar hypoxia on the pulmonary circulation and lung mechanics after cromolyn sodium and U-60,257 in lambs. | 1992 | J. Dev. Physiol. | pmid:1304007 |
| Jiang K | [The study of occurrence mechanism in acute and chronic cerebral vasospasm]. | 1992 | Zhonghua Shen Jing Jing Shen Ke Za Zhi | pmid:1304997 |
| Di Minno G et al. | In vivo platelet activation in homozygous cystathionine beta-synthase deficiency: a probucol-sensitive phenomenon. | 1992 | Trans. Assoc. Am. Physicians | pmid:1308991 |
| Bendele AM et al. | Anti-inflammatory activity of BF389, a Di-T-butylphenol, in animal models of arthritis. | 1992 | J. Pharmacol. Exp. Ther. | pmid:1309875 |
| Takashio T et al. | Inhibitory effect of pindolol on hypoxic pulmonary vasoconstriction. | 1992 | Am. J. Physiol. | pmid:1310232 |
| Yu SM et al. | Dicentrine, a novel antiplatelet agent inhibiting thromboxane formation and increasing the cyclic AMP level of rabbit platelets. | 1992 | Biochem. Pharmacol. | pmid:1310852 |
| Spaethe SM et al. | Guinea pig whole blood 5-lipoxygenase assay: utility in the assessment of potential 5-lipoxygenase inhibitors. | 1992 | Biochem. Pharmacol. | pmid:1310855 |
| Ryo R et al. | Deficiency of P62, a putative collagen receptor, in platelets from a patient with defective collagen-induced platelet aggregation. | 1992 | Am. J. Hematol. | pmid:1311144 |
| Sata T et al. | Paraquat-induced lung injury: prevention by N-tert-butyl-alpha-phenylnitrone, a free-radical spin-trapping agent. | 1992 | Am. J. Physiol. | pmid:1311515 |
| Martinez GR et al. | 3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase. | 1992 | J. Med. Chem. | pmid:1311763 |
| Aepfelbacher M et al. | Bacterial lipopolysaccharide up-regulates platelet-activating factor-stimulated Ca2+ mobilization and eicosanoid release in human Mono Mac 6 cells. | 1992 | J. Immunol. | pmid:1312103 |
| Panos RJ et al. | Alterations in eicosanoid production by rat alveolar type II cells isolated after silica-induced lung injury. | 1992 | Am. J. Respir. Cell Mol. Biol. | pmid:1312852 |
| Rabinovici R et al. | Platelet activating factor mediates interleukin-2-induced lung injury in the rat. | 1992 | J. Clin. Invest. | pmid:1314853 |
| Kitsukawa Y et al. | Effect of ingestion of eicosapentaenoic acid ethyl ester on carrageenan-induced colitis in guinea pigs. | 1992 | Gastroenterology | pmid:1316857 |
| Longhurst JC et al. | Increased concentration of leukotriene B4 but not thromboxane B2 in intestinal lymph of cats during brief ischemia. | 1992 | Am. J. Physiol. | pmid:1317130 |
| Farrukh IS and Michael JR | Cellular mechanisms that control pulmonary vascular tone during hypoxia and normoxia. Possible role of Ca2+ATPases. | 1992 | Am. Rev. Respir. Dis. | pmid:1317692 |
| Chen CX et al. | Inhibitory effect of rhynchophylline on platelet aggregation and thrombosis. | 1992 | Zhongguo Yao Li Xue Bao | pmid:1317985 |
| Imaizumi A et al. | Pertussis toxin induces bronchopulmonary hyperresponsiveness in guinea-pigs while antagonizing the effects of formyl-L-methionyl-L-leucyl-L-phenylalanine. | 1992 | Eur. J. Pharmacol. | pmid:1318209 |
| Sumner H et al. | Inhibition of 5-lipoxygenase and cyclo-oxygenase in leukocytes by feverfew. Involvement of sesquiterpene lactones and other components. | 1992 | Biochem. Pharmacol. | pmid:1319159 |
| Baker AJ and Fuller RW | Effect of cyclic adenosine monophosphate, 5'-(N-ethylcarboxyamido)-adenosine and methylxanthines on the release of thromboxane and lysosomal enzymes from human alveolar macrophages and peripheral blood monocytes in vitro. | 1992 | Eur. J. Pharmacol. | pmid:1319339 |
| Koyama S et al. | Dibutyryl cyclic AMP attenuates lung responses induced by endotoxin in conscious sheep. | 1992 | Am. Rev. Respir. Dis. | pmid:1320821 |