Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Basal Ganglia Hemorrhage D020145 1 associated lipids
Edema, Cardiac D004489 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Radiculopathy D011843 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Bluetongue D001819 1 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Heart Septal Defects D006343 2 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Weil Disease D014895 2 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Drowning D004332 2 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Infertility D007246 3 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Contusions D003288 3 associated lipids
Macular Edema D008269 3 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Yang Deficiency D016711 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Bronchopulmonary Sequestration D001998 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Jejunal Diseases D007579 3 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Streptococcal Infections D013290 4 associated lipids
Retinal Diseases D012164 4 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Thrombasthenia D013915 4 associated lipids
Menorrhagia D008595 4 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Diseases in Twins D004200 4 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Heart Valve Diseases D006349 4 associated lipids
beta-Thalassemia D017086 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
Placenta Diseases D010922 5 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Facial Pain D005157 5 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Mastocytosis D008415 5 associated lipids
Bartter Syndrome D001477 5 associated lipids
Hypercapnia D006935 5 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Asthenia D001247 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Sclerosis D012598 5 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Thrombophilia D019851 6 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Coronary Stenosis D023921 6 associated lipids
Sneezing D012912 6 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Thromboembolism D013923 6 associated lipids
Bronchitis D001991 6 associated lipids
Intermittent Claudication D007383 6 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Tachycardia D013610 7 associated lipids
Dyslipidemias D050171 7 associated lipids
Keratitis D007634 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Varicose Veins D014648 7 associated lipids
Behcet Syndrome D001528 7 associated lipids
Agranulocytosis D000380 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Enteritis D004751 8 associated lipids
Fetal Diseases D005315 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Simmons PM et al. The release of leukotriene B4 during experimental inflammation. 1983 Biochem. Pharmacol. pmid:6305369
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Fletcher JR et al. Thromboxane inhibition in gram-negative sepsis fails to improve survival. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221586
Socini A et al. Fish oil administration lowers prostacyclin production and the antiaggregatory activity of aortic walls more effectively than platelet aggregation and thromboxane in the rat. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221591
Mandrovnaia NV et al. [Age-related changes in prostacyclin and thromboxane B2 biosynthesis under normal conditions and in arterial hypertension]. 1983 Kardiologiia pmid:6366325
Abiko Y et al. The stimulation of macrophage prostaglandin E2 and thromboxane B2 secretion by Streptococcus mutans insoluble glucans. 1983 FEBS Lett. pmid:6403385
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Gordon PR et al. Platelet arachidonate metabolism and platelet function in zinc-deficient rats. 1983 J. Nutr. pmid:6403678
Okegawa T et al. Endotoxin induces chronic prostaglandin and thromboxane synthesis from ureter-obstructed kidneys: role of inflammatory cells. 1983 J. Pharmacol. Exp. Ther. pmid:6403696
Ellsworth ML et al. Pulmonary prostacyclin production with increased flow and sympathetic stimulation. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6415017
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Bailey IA et al. Effects of vascular trauma and transient myocardial ischaemia on coronary venous prostaglandin levels in the dog. 1983 Cardiovasc. Res. pmid:6688202
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Wilson L and Huang LS Effects of the fetal-placental unit on uterine prostaglandin levels at term in the pregnant rat. 1983 Prostaglandins pmid:6688474
Hidaka T et al. Thromboxane formation from arachidonic acid and prostaglandin H2 in rabbit spleen. 1983 J. Biochem. pmid:6404897
Gerozissis K and Dray F In-vitro prostanoid production by the rat vas deferens. 1983 J. Reprod. Fertil. pmid:6572721
Schleimer RP et al. Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. 1983 J. Clin. Invest. pmid:6134755
Okahara T et al. Zonal heterogeneity of prostaglandin and thromboxane release in the dog kidney. 1983 Prostaglandins pmid:6575405
Reuben SR et al. Effects of dazoxiben on exercise performance in chronic stable angina. 1983 Br J Clin Pharmacol pmid:6402000
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Förster W and Pönicke K Influence of sympathomimetic drugs (1-phenyl-2-amino-ethan-1-ol derivatives) on the biosynthesis of prostaglandins and thromboxane B2. 1983 Br. J. Pharmacol. pmid:6403094
Nenci GG et al. Platelet malondialdehyde production kinetics after cyclooxygenase block. A study performed with a modified high sensitivity assay. 1983 Haemostasis pmid:6404715
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Lewy RI Role of thromboxanes in vasotonic versus vaso-occlusive angina. 1983 Arch Mal Coeur Vaiss pmid:6407435
Butler RR et al. Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production. 1983 J. Pharmacol. Exp. Ther. pmid:6339712