Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hartung HP | Acetyl glyceryl ether phosphorylcholine (platelet-activating factor) mediates heightened metabolic activity in macrophages. Studies on PGE, TXB2 and O2- production, spreading, and the influence of calmodulin-inhibitor W-7. | 1983 | FEBS Lett. | pmid:6309563 |
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Fletcher JR et al. | Thromboxane inhibition in gram-negative sepsis fails to improve survival. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221586 |
Socini A et al. | Fish oil administration lowers prostacyclin production and the antiaggregatory activity of aortic walls more effectively than platelet aggregation and thromboxane in the rat. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221591 |
Mandrovnaia NV et al. | [Age-related changes in prostacyclin and thromboxane B2 biosynthesis under normal conditions and in arterial hypertension]. | 1983 | Kardiologiia | pmid:6366325 |
Abiko Y et al. | The stimulation of macrophage prostaglandin E2 and thromboxane B2 secretion by Streptococcus mutans insoluble glucans. | 1983 | FEBS Lett. | pmid:6403385 |
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Mehta P et al. | Inhibitory effects of diltiazem on platelet activation caused by ionophore A23187 plus ADP or epinephrine in subthreshold concentrations. | 1983 | J. Lab. Clin. Med. | pmid:6411841 |
Gordon PR et al. | Platelet arachidonate metabolism and platelet function in zinc-deficient rats. | 1983 | J. Nutr. | pmid:6403678 |
Okegawa T et al. | Endotoxin induces chronic prostaglandin and thromboxane synthesis from ureter-obstructed kidneys: role of inflammatory cells. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6403696 |
Ellsworth ML et al. | Pulmonary prostacyclin production with increased flow and sympathetic stimulation. | 1983 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6415017 |
Halushka PV et al. | Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism. | 1983 | Am. J. Med. | pmid:6687979 |
Tsukatani E | Etiology of EPH-gestosis from the viewpoint of dynamics of vasoactive prostanoid, lipid peroxides and vitamin E. | 1983 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:6688085 |
Fischer S et al. | In vivo and in vitro effects of nafazatrom (Bay g 6575), an antithrombotic compound, on arachidonic acid metabolism in platelets and vascular tissue. | 1983 | Biochem. Pharmacol. | pmid:6688182 |
Bailey IA et al. | Effects of vascular trauma and transient myocardial ischaemia on coronary venous prostaglandin levels in the dog. | 1983 | Cardiovasc. Res. | pmid:6688202 |
Srivastava KC and Awasthi KK | Separation and quantitative determination of radiolabeled prostaglandins, thromboxanes, 6-keto-prostaglandin F1 alpha and other arachidonic acid metabolites produced in biological material. | 1983 | J. Chromatogr. | pmid:6688256 |
Wilson L and Huang LS | Effects of the fetal-placental unit on uterine prostaglandin levels at term in the pregnant rat. | 1983 | Prostaglandins | pmid:6688474 |
Hidaka T et al. | Thromboxane formation from arachidonic acid and prostaglandin H2 in rabbit spleen. | 1983 | J. Biochem. | pmid:6404897 |
Gerozissis K and Dray F | In-vitro prostanoid production by the rat vas deferens. | 1983 | J. Reprod. Fertil. | pmid:6572721 |
Schleimer RP et al. | Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. | 1983 | J. Clin. Invest. | pmid:6134755 |
Okahara T et al. | Zonal heterogeneity of prostaglandin and thromboxane release in the dog kidney. | 1983 | Prostaglandins | pmid:6575405 |
Reuben SR et al. | Effects of dazoxiben on exercise performance in chronic stable angina. | 1983 | Br J Clin Pharmacol | pmid:6402000 |
Rojas J et al. | Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep. | 1983 | Pediatr. Res. | pmid:6402752 |
Gimenez T et al. | Fetal-maternal secretion of prostaglandins in the cow. | 1983 | Prostaglandins | pmid:6576447 |
Förster W and Pönicke K | Influence of sympathomimetic drugs (1-phenyl-2-amino-ethan-1-ol derivatives) on the biosynthesis of prostaglandins and thromboxane B2. | 1983 | Br. J. Pharmacol. | pmid:6403094 |
Nenci GG et al. | Platelet malondialdehyde production kinetics after cyclooxygenase block. A study performed with a modified high sensitivity assay. | 1983 | Haemostasis | pmid:6404715 |
Sharon P et al. | Prostanoid synthesis by cultured gastric and duodenal mucosa: Possible role in the pathogenesis of duodenal ulcer. | 1983 | Scand. J. Gastroenterol. | pmid:6584967 |
Lewy RI | Role of thromboxanes in vasotonic versus vaso-occlusive angina. | 1983 | Arch Mal Coeur Vaiss | pmid:6407435 |
Butler RR et al. | Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6339712 |