Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Edema, Cardiac D004489 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Radiculopathy D011843 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Bluetongue D001819 1 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
Foot Rot D005535 1 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Heart Septal Defects D006343 2 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Weil Disease D014895 2 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Drowning D004332 2 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Jejunal Diseases D007579 3 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Infertility D007246 3 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Macular Edema D008269 3 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Yang Deficiency D016711 3 associated lipids
Contusions D003288 3 associated lipids
Aortic Rupture D001019 3 associated lipids
Bronchopulmonary Sequestration D001998 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Retinal Diseases D012164 4 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Thrombasthenia D013915 4 associated lipids
Menorrhagia D008595 4 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Diseases in Twins D004200 4 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Pulmonary Embolism D011655 5 associated lipids
beta-Thalassemia D017086 5 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
Placenta Diseases D010922 5 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Facial Pain D005157 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Mastocytosis D008415 5 associated lipids
Bartter Syndrome D001477 5 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypercapnia D006935 5 associated lipids
Asthenia D001247 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Sclerosis D012598 5 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Coronary Stenosis D023921 6 associated lipids
Sneezing D012912 6 associated lipids
Bronchitis D001991 6 associated lipids
Intermittent Claudication D007383 6 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Thromboembolism D013923 6 associated lipids
Thrombophilia D019851 6 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Varicose Veins D014648 7 associated lipids
Behcet Syndrome D001528 7 associated lipids
Agranulocytosis D000380 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Tachycardia D013610 7 associated lipids
Dyslipidemias D050171 7 associated lipids
Keratitis D007634 7 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Renal Artery Obstruction D012078 8 associated lipids
Enteritis D004751 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Herrick AL et al. Von Willebrand factor, thrombomodulin, thromboxane, beta-thromboglobulin and markers of fibrinolysis in primary Raynaud's phenomenon and systemic sclerosis. 1996 Ann. Rheum. Dis. pmid:8712862
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Myers SI et al. Long-term resuscitation of hemorrhage/reperfusion injury (H/R) stimulates renal PGE2 release. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8832762
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Closa D et al. Hepatic involvement in pancreatitis-induced lung damage. 1996 Am. J. Physiol. pmid:8772495
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Ravn HB et al. Magnesium inhibits human platelets. 1996 Blood Coagul. Fibrinolysis pmid:8735829
Young JM et al. Human whole blood assays for inhibition of prostaglandin G/H synthases-1 and -2 using A23187 and lipopolysaccharide stimulation of thromboxane B2 production. 1996 Inflamm. Res. pmid:8737748
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Ko FN et al. Mechanism of action of p-chlorobiphenyl on the inhibition of platelet aggregation. 1996 J. Pharm. Pharmacol. pmid:8794990
Yoshida T et al. Abnormal prostanoid metabolism in lupus nephritis and the effects of a thromboxane A2 synthetase inhibitor, DP-1904. 1996 Lupus pmid:8743126
Fritsche KL and Cassity NA Metabolism of [3H]arachidonic acid by n-3 polyunsaturated fatty acid-enriched piglet alveolar macrophages. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8981628
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Kruse-Elliott KT et al. Attenuation of endotoxin-induced pathophysiology by a new potent PAF receptor antagonist. 1996 Shock pmid:8721386
Li KL et al. The effect of ketoprofen creams on periodontal disease in rhesus monkeys. 1996 J. Periodont. Res. pmid:8971650
Yanase T et al. Dibutyryl cAMP improves systemic vasoconstriction caused by endotoxin in dogs. 1996 Shock pmid:8721389
Grauer GF et al. Effects of dietary n-3 fatty acid supplementation versus thromboxane synthetase inhibition on gentamicin-induced nephrotoxicosis in healthy male dogs. 1996 Am. J. Vet. Res. pmid:8725828
Delatour P et al. Pharmacodynamics and chiral pharmacokinetics of carprofen in calves. 1996 Br. Vet. J. pmid:8680841
Jensen N et al. Recovery of endothelial cells and prostanoid production in endothelial cell-seeded grafts. 1996 Eur J Vasc Endovasc Surg pmid:8696898
Nosál R et al. The H1-histamine antagonist Dithiaden inhibits human platelets in vitro. 1996 Inflamm. Res. pmid:8696916
Janssen PL et al. Consumption of ginger (Zingiber officinale roscoe) does not affect ex vivo platelet thromboxane production in humans. 1996 Eur J Clin Nutr pmid:8933126
Liao CH et al. Antiplatelet effect of demethyldiisoeugenol. 1996 Can. J. Physiol. Pharmacol. pmid:9022830
Tarnow P et al. Effects of D-myo-Inositol-1,2,6-triphosphate on eicosanoid formation in burned skin. 1996 J. Surg. Res. pmid:8606494
Okada M et al. Two mechanisms for platelet-mediated killing of tumour cells: one cyclo-oxygenase dependent and the other nitric oxide dependent. 1996 Immunology pmid:8911154
Berdeaux O et al. Effects of a trans isomer of arachidonic acid on rat platelet aggregation and eicosanoid production. 1996 J. Lipid Res. pmid:8906600
Cuiper LL et al. Systemic and pulmonary hypertension after abrupt cessation of prostacyclin: role of thromboxane A2. 1996 J. Appl. Physiol. pmid:8847301
Horiguchi T et al. Pulmonary responses to heparin-protamine complexes: the effects of age and species. 1996 J. Appl. Physiol. pmid:8847332
Gabriel A et al. Influence of prostaglandin E1 on tissue ischemia during surgical repair of the abdominal aorta. 1996 J. Cardiothorac. Vasc. Anesth. pmid:8850397
Chen SJ et al. Antiplatelet and calcium inhibitory properties of eugenol and sodium eugenol acetate. 1996 Gen. Pharmacol. pmid:8853295
Suehiro T et al. Thromboxane A2 in preservation-reperfusion injury: the effect of thromboxane A2 synthetase inhibitor. 1996 J. Surg. Res. pmid:8632642
Garvin PJ et al. Evaluation of the thromboxane A2 synthetase inhibitor OKY-046 in a warm ischemia-reperfusion rat model. 1996 Transplantation pmid:8633364
Isenring P et al. Eicosanoid modulation of the norepinephrine effect on blood pressure and renal hemodynamics in humans. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8992495
Leung S et al. Isolation and purification of anticardiolipin antibody from plasma of a patient with antiphospholipid syndrome: induced generation of platelet thromboxane A2 synthesis. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:9014216
Hirakata H et al. Sevoflurane inhibits human platelet aggregation and thromboxane A2 formation, possibly by suppression of cyclooxygenase activity. 1996 Anesthesiology pmid:8968193
Sheu JR et al. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. 1996 Eur. J. Pharmacol. pmid:9016940
Leung LK and Glauert HP Reduction of the concentrations of prostaglandins E2 and F2alpha, and thromboxane B2 in cultured rat hepatocytes treated with the peroxisome proliferator ciprofibrate. 1996 Toxicol. Lett. pmid:8644126
Karck U et al. PGE2 and PGF2 alpha release by human peritoneal macrophages in endometriosis. 1996 Prostaglandins pmid:8900443
Blache D Enhanced arachidonic acid and calcium metabolism in cholesteryl sulfate-enriched rat platelets. 1996 J Lipid Mediat Cell Signal pmid:8925194
Pancera P et al. Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8860111
van der Weiden RM et al. Prostanoid excretion in incipient singleton and twin pregnancies. 1996 Am. J. Obstet. Gynecol. pmid:9065139
Cheng Z et al. Pharmacokinetics and pharmacodynamics of phenylbutazone and oxyphenbutazone in the donkey. 1996 J. Vet. Pharmacol. Ther. pmid:8735424
Pregnolato P et al. Effect of diets containing different amounts of precursor and derivative fatty acids on serum TXB2. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8981629
Siler-Khodr TM et al. Dose-related action of estradiol on placental prostanoid prediction. 1996 Prostaglandins pmid:8873234
Prié S et al. Eosinophils and neutrophils modify arachidonic acid-induced relaxation of guinea-pig trachea. 1996 Eur. J. Pharmacol. pmid:8997620
Lechi C et al. In vitro study of the anti-aggregating activity of two nitroderivatives of acetylsalicylic acid. 1996 Blood Coagul. Fibrinolysis pmid:8735820
Cirino G et al. Indomethacin and thromboxane A2/prostaglandin H2 antagonist SQ29,548 impair in vitro contractions of aortic rings of ex vivo-treated lipopolysaccharide rats. 1996 J Lipid Mediat Cell Signal pmid:8925198
Hirashima Y et al. Prevention of cerebrovasospasm following subarachnoid hemorrhage in rabbits by the platelet-activating factor antagonist, E5880. 1996 J. Neurosurg. pmid:8622157
Korn RL et al. The effects of Carmeda Bioactive Surface on human blood components during simulated extracorporeal circulation. 1996 J. Thorac. Cardiovasc. Surg. pmid:8622305
McAdam B et al. Transdermal modification of platelet function: an aspirin patch system results in marked suppression of platelet cyclooxygenase. 1996 J. Pharmacol. Exp. Ther. pmid:8627531
Chou TC et al. The inhibitory effect of 2-thienyl 2'-hydroxyphenyl ketone (C85) on platelet thromboxane formation. 1996 Thromb. Res. pmid:8897698
Harada Y et al. Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy. 1996 Prostaglandins pmid:8900441
Saji T et al. [Short- and long-term effects of the new oral prostacyclin analogue, beraprost sodium, in patients with severe pulmonary hypertension]. 1996 J Cardiol pmid:8642506
Tsunomori M et al. 15-Hydroperoxyeicosapentaenoic acid inhibits arachidonic acid metabolism in rabbit platelets more potently than eicosapentaenoic acid. 1996 Biochim. Biophys. Acta pmid:8679681
Livingston ER et al. Increased activation of the coagulation and fibrinolytic systems leads to hemorrhagic complications during left ventricular assist implantation. 1996 Circulation pmid:8901751
Serebruany VL et al. Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine. 1996 Pharmacology pmid:8902873
Martin W et al. Respiratory dysfunction and white cell activation following cardiopulmonary bypass: comparison of membrane and bubble oxygenators. 1996 Eur J Cardiothorac Surg pmid:8905281
Montuschi P et al. Tachykinin NK2 receptor antagonists decrease eicosanoid release in lung anaphylaxis. 1996 Eur. J. Pharmacol. pmid:8905345
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Schmid P et al. Passive smoking and platelet thromboxane. 1996 Thromb. Res. pmid:8907294
Chello M et al. Reduction by indobufen of neutrophil activation in peripheral arterial occlusive disease. 1996 J. Cardiovasc. Pharmacol. pmid:8907804
Szekacs B et al. Prostacyclin and thromboxane production of rat and cat arterial tissue is altered independently by several vasoactive substances. 1996 Prostaglandins pmid:8908622
Serebruany VL et al. Hemostatic changes after early versus late intracoronary magnesium during acute myocardial infarction in swine. 1996 J. Cardiovasc. Pharmacol. pmid:8961080
Gries A et al. Lipoprotein(a) inhibits collagen-induced aggregation of thrombocytes. 1996 Arterioscler. Thromb. Vasc. Biol. pmid:8963722
Sreedhara R et al. Uremic patients have decreased shear-induced platelet aggregation mediated by decreased availability of glycoprotein IIb-IIIa receptors. 1996 Am. J. Kidney Dis. pmid:8604704
Fukushima C et al. Inhibitory effect of thromboxane A2 synthetase inhibitor, DP-1904, on antigen-induced contraction of human lung parenchyma. 1996 Ann. Allergy Asthma Immunol. pmid:8970439
Shibasaki T et al. Mizoribine reduces urinary protein excretion in rats given puromycin aminonucleoside. 1996 Am. J. Nephrol. pmid:8919236
González ET et al. Prostanoid modulation of glucose transport in isolated diabetic rat uterus. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8804128
Takase B et al. Arachidonic acid metabolites in acute myocardial infarction. 1996 Angiology pmid:8686958
Mustad V et al. Seasonal variation in parameters related to coronary heart disease risk in young men. 1996 Atherosclerosis pmid:8879440
Selley ML et al. The effect of cholesterol oxidation products on human platelet aggregation. 1996 Thromb. Res. pmid:8885139
Carbajal D et al. Possible cytoprotective mechanism in rats of D-002, an anti-ulcerogenic product isolated from beeswax. 1996 J. Pharm. Pharmacol. pmid:8887738
Nowak J et al. Thromboxane metabolite excretion in patients with hand-arm vibration syndrome. 1996 Clin Physiol pmid:8842572
Huang JZ et al. Study on characteristics of blast-fragment combined injury in dogs. 1996 J Trauma pmid:8606426
Fekkes D et al. Eicosanoid and amino acid metabolism in transient acute psychoses with psychedelic symptoms. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8804122
Feng J et al. Beneficial effects of iloprost cardioplegia in ischemic arrest in isolated working rat heart. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8804125
Gennaro M et al. Perfluorocarbon emulsion prevents eicoasanoid release in skeletal muscle ischemia and reperfusion. 1996 Cardiovasc Surg pmid:8782946
Fimognari FL et al. Associated daily biosynthesis of cortisol and thromboxane A2: a preliminary report. 1996 J. Lab. Clin. Med. pmid:8759943
Xing X and Xia S [The injury of liver sinusoidal endothelial cells in a rat's isolated liver perfusion (ILP) model for regional chemotherapy]. 1996 Zhonghua Wai Ke Za Zhi pmid:9275689
Kuroiwa M et al. Effects of granulocyte colony-stimulating factor on the hemostatic system in healthy volunteers. 1996 Int. J. Hematol. pmid:8762814
Fuse I et al. Vascular thromboxane formation in hemostasis mechanism: correlation between bleeding time and vascular TXB2 in a patient with congenital platelet cyclo-oxygenase deficiency. 1996 Int. J. Hematol. pmid:8762815
Yoshida SH et al. Dietary Juniperis virginiensis seed oil decreased pentobarbital-associated mortalities among DBA/1 mice treated with collagen-adjuvant emulsions. 1996 J Lipid Mediat Cell Signal pmid:8816989
Galbraith EA and McKellar QA Protein binding and in vitro serum thromboxane B2 inhibition by flunixin meglumine and meclofenamic acid in dog, goat and horse blood. 1996 Res. Vet. Sci. pmid:8819199
Davì G et al. Influence of metabolic control on thromboxane biosynthesis and plasma plasminogen activator inhibitor type-1 in non-insulin-dependent diabetes mellitus. 1996 Thromb. Haemost. pmid:8819248
Wagner RS et al. Activation of thromboxane A2 receptors alters lipopolysaccharide-induced adherence of THP-1 cells. 1996 Shock pmid:8821102
Nishisho T et al. Experimental and clinical studies of eicosanoids in cerebrospinal fluid after spinal cord injury. 1996 Neurosurgery pmid:8905750
Watanabe M et al. [Changes in platelet sensitivity to thromboxane A2 in pediatric patients with nephrotic syndrome]. 1996 Nihon Jinzo Gakkai Shi pmid:8828355
Meenan J et al. Lexipafant (BB-882), a platelet activating factor receptor antagonist, ameliorates mucosal inflammation in an animal model of colitis. 1996 Eur J Gastroenterol Hepatol pmid:8823572
Giulian D et al. Activated microglia are the principal glial source of thromboxane in the central nervous system. 1996 Neurochem. Int. pmid:8808790
Zhen ZY et al. Experimental study on microthrombi and myocardial injuries. 1996 Microvasc. Res. pmid:8812763
Pace-Asciak CR et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. 1996 Clin. Chim. Acta pmid:8814965
Uhlig S et al. Cyclooxygenase-2-dependent bronchoconstriction in perfused rat lungs exposed to endotoxin. 1996 Mol. Med. pmid:8784790