Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dalli E et al. | Effects of hawthorn (Crataegus laevigata) on platelet aggregation in healthy volunteers. | 2011 | Thromb. Res. | pmid:21737127 |
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Shen L et al. | In vivo oxidation, platelet activation and simultaneous occurrence of natural immunity in atherosclerosis-prone mice. | 2011 | Isr. Med. Assoc. J. | pmid:21845968 |
Mattiello T et al. | Aspirin extrusion from human platelets through multidrug resistance protein-4-mediated transport: evidence of a reduced drug action in patients after coronary artery bypass grafting. | 2011 | J. Am. Coll. Cardiol. | pmid:21816313 |
Ramadan E et al. | Chronic valproate treatment blocks D2-like receptor-mediated brain signaling via arachidonic acid in rats. | 2011 | Neuropharmacology | pmid:21839100 |
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Capodanno D et al. | Pharmacodynamic effects of different aspirin dosing regimens in type 2 diabetes mellitus patients with coronary artery disease. | 2011 | Circ Cardiovasc Interv | pmid:21386092 |
Yan LG et al. | Injectable caltrop fruit saponin protects against ischemia-reperfusion injury in rat brain. | 2011 | Am. J. Chin. Med. | pmid:21476209 |
Liu JQ et al. | Effects of tanshinone IIA, a major component of Salvia miltiorrhiza, on platelet aggregation in healthy newborn piglets. | 2011 | J Ethnopharmacol | pmid:21453766 |
Halawani SH et al. | Aspirin failure in patients presenting with acute cerebrovascular ischaemia. | 2011 | Thromb. Haemost. | pmid:21544317 |
Gonçalves LH et al. | Urinary 11-dehydro thromboxane B₂ levels in type 2 diabetic patients before and during aspirin intake. | 2011 | Clin. Chim. Acta | pmid:21510926 |
Basselin M et al. | Anti-inflammatory effects of chronic aspirin on brain arachidonic acid metabolites. | 2011 | Neurochem. Res. | pmid:20981485 |
Oates JC et al. | Selective cyclooxygenase-2 inhibitor suppresses renal thromboxane production but not proliferative lesions in the MRL/lpr murine model of lupus nephritis. | 2011 | Am. J. Med. Sci. | pmid:20924284 |
Grove EL et al. | Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery disease. | 2011 | J. Thromb. Haemost. | pmid:20955349 |
Basselin M et al. | Imaging upregulated brain arachidonic acid metabolism in HIV-1 transgenic rats. | 2011 | J. Cereb. Blood Flow Metab. | pmid:20664612 |
Ceprnja M et al. | Oxidative stress markers in patients with post-traumatic stress disorder. | 2011 | Coll Antropol | pmid:22397253 |
Toliopoulos IK et al. | Inhibition of platelet aggregation and immunomodulation of NK lymphocytes by administration of ascorbic acid. | 2011 | Indian J. Exp. Biol. | pmid:22403863 |
Lordkipanidzé M et al. | Heterogeneity in platelet cyclooxygenase inhibition by aspirin in coronary artery disease. | 2011 | Int. J. Cardiol. | pmid:20207433 |