Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Folkert VW and Schlondorff D | Prostaglandin synthesis in isolated glomeruli. | 1979 | Prostaglandins | pmid:441427 |
Parker CW et al. | Formation of thromboxane B2 and hydroxyarachidonic acids in purified human lymphocytes in the presence and absence of PHA. | 1979 | J. Immunol. | pmid:448099 |
Needleman P et al. | Platelet and blood vessel arachidonate metabolism and interactions. | 1979 | J. Clin. Invest. | pmid:372240 |
Morley J et al. | Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes. | 1979 | Prostaglandins | pmid:493559 |
Meyers KM et al. | A dominant role of thromboxane formation in secondary aggregation of platelets. | 1979 | Nature | pmid:503210 |
Daniel EE et al. | Prostaglandins and myogenic control of tension in lower esophageal sphincter in vitro. | 1979 | Prostaglandins | pmid:379920 |
Russell FA and Deykin D | The use of high pressure liquid chromatography (HPLC) for the separation of radiolabeled arachidonic acid and its metabolities produced by thrombin-treated human platelets. I. The validation of the technique. | 1979 | Prostaglandins | pmid:523671 |
Roberts LJ et al. | Prostaglandin thromboxane, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid production by ionophore-stimulated rat serosal mast cells. | 1979 | Biochim. Biophys. Acta | pmid:389290 |
Dutilh CE et al. | Study of the two pathways for arachidonate oxygenation in blood platelets. | 1979 | Lipids | pmid:34075 |
Dembińska-Kièć A et al. | Prostacyclin-dependent differences in TXA2 formation by platelets from normal and atherosclerotic rabbits. | 1979 | Atherosclerosis | pmid:224890 |
Kass MA and Holmberg NJ | Prostaglandin and thromboxane synthesis by microsomes of rabbit ocular tissues. | 1979 | Invest. Ophthalmol. Vis. Sci. | pmid:761971 |
Boura AL and Murphy RD | Thromboxane B2 inhibits prostaglandin E2 inactivation by the rat isolated perfused lung. | 1978 Jul-Aug | Clin. Exp. Pharmacol. Physiol. | pmid:699382 |
Marion J and Wolfe LS | Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. | 1978 | Prostaglandins | pmid:704928 |
Kitchen EA et al. | Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes. | 1978 | Prostaglandins | pmid:704931 |
Sors H et al. | Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry. | 1978 | Prostaglandins | pmid:704933 |
Turk J et al. | Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography. | 1978 | Prostaglandins | pmid:704934 |
Raz A and Aharony D | Prostaglandin biosynthesis in platelets: demonstration and role of prostaglandin H2 leads to E2 isomerase. | 1978 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:705027 |
Chang WC et al. | Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma. | 1978 | Biochem. Pharmacol. | pmid:619892 |
Goetzl EJ and Gorman RR | Chemotactic and chemokinetic stimulation of human eosinophil and neutrophil polymorphonuclear leukocytes by 12-L-hydroxy-5,8,10-heptadecatrienoic acid (HHT). | 1978 | J. Immunol. | pmid:621391 |
Hamberg M et al. | A method for measurement of platelet regeneration in man. | 1978 | Prostaglandins Med | pmid:104315 |