Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cathcart MC et al. | Thromboxane synthase expression and correlation with VEGF and angiogenesis in non-small cell lung cancer. | 2014 | Biochim. Biophys. Acta | pmid:24480048 |
Chou YI et al. | Correlations of platelet-derived microparticles with thromboxane B2, platelet-activating factor, endothelin-1, and neutrophil to lymphocyte ratio in patients with coronary intermediate lesions. | 2014 | Biomarkers | pmid:25391885 |
Fuentes E et al. | A novel role of Eruca sativa Mill. (rocket) extract: antiplatelet (NF-κB inhibition) and antithrombotic activities. | 2014 | Nutrients | pmid:25514563 |
John F et al. | Elevated levels of leukotriene B4 and thromboxane B2 distinguish chest pain of cardiac and non cardiac origin. | 2013 May-Jun | Indian Heart J | pmid:23809385 |
Dudley A et al. | Cyclooxygenase expression and platelet function in healthy dogs receiving low-dose aspirin. | 2013 Jan-Feb | J. Vet. Intern. Med. | pmid:23278865 |
Maenthaisong R et al. | Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755755 |
Wu G et al. | Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia. | 2013 | Chem. Pharm. Bull. | pmid:23207681 |
Shi JJ and Huang LF | [Effects of transcutaneous electrical acupoint stimulation of "Zusanli" (ST 36) on gastric mucosal injury in exercise stress-induced gastric ulcer rats]. | 2013 | Zhen Ci Yan Jiu | pmid:24006661 |
Steib CJ et al. | Functional relevance of the cannabinoid receptor 2 - heme oxygenase pathway: a novel target for the attenuation of portal hypertension. | 2013 | Life Sci. | pmid:24007798 |
DeFilippis AP et al. | Thromboxane A(2) generation, in the absence of platelet COX-1 activity, in patients with and without atherothrombotic myocardial infarction. | 2013 | Circ. J. | pmid:23985963 |
Siennicka A et al. | Haemostatic factors and intraluminal thrombus thickness in abdominal aortic aneurysm. Is secondary fibrinolysis relevant? | 2013 | J. Physiol. Pharmacol. | pmid:23959729 |
Kleinbongard P et al. | Aspirate from human stented native coronary arteries vs. saphenous vein grafts: more endothelin but less particulate debris. | 2013 | Am. J. Physiol. Heart Circ. Physiol. | pmid:23934849 |
Yamamoto M et al. | Effects of continuous ingestion of hesperidin and glucosyl hesperidin on vascular gene expression in spontaneously hypertensive rats. | 2013 | J. Nutr. Sci. Vitaminol. | pmid:24418882 |
Sadilkova L et al. | The effect of selected pre-analytical phase variables on plasma thromboxane Aâ‚‚ measurements in humans. | 2013 | Int J Lab Hematol | pmid:22908995 |
Brentnall C et al. | Influence of oxytetracycline on carprofen pharmacodynamics and pharmacokinetics in calves. | 2013 | J. Vet. Pharmacol. Ther. | pmid:22913421 |
Yi X et al. | Platelet response to aspirin in Chinese stroke patients is independent of genetic polymorphisms of COX-1 C50T and COX-2 G765C. | 2013 | J. Atheroscler. Thromb. | pmid:22972377 |
Broekema FI et al. | In vivo hemostatic efficacy of polyurethane foam compared to collagen and gelatin. | 2013 | Clin Oral Investig | pmid:22855267 |
McMahon GS et al. | Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase. Findings from a randomised controlled trial. | 2013 | Thromb. Haemost. | pmid:23494053 |
Dharmasaroja PA et al. | Aspirin nonresponders in patients with ischaemic stroke. | 2013 | Blood Coagul. Fibrinolysis | pmid:23429255 |
Shiraishi M et al. | Cholesterol enrichment of rabbit platelets enhances the Ca(2+) entry pathway induced by platelet-derived secondary feedback agonists. | 2013 | Life Sci. | pmid:23499558 |