Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Murphy NP et al. | Functional relevance of the expression of ligand-induced binding sites in the response to platelet GP IIb/IIIa antagonists in vivo. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9694954 |
| Levy M et al. | Cerebrospinal fluid prostaglandins after systemic dipyrone intake. | 1998 | Clin. Pharmacol. Ther. | pmid:9695726 |
| Fagugli RM et al. | Reduction of renal functional reserve in kidney transplant recipients: a possible role of arachidonic acid metabolism alterations. | 1998 | Clin. Nephrol. | pmid:9696430 |
| Iida T et al. | The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats. | 1998 | Pancreas | pmid:9700944 |
| Ingster LM and Feinleib M | Salicylate intake and cardiovascular disease: Ingster and Feinleib respond to Hu and Willett. | 1998 | Am J Public Health | pmid:9702172 |
| Hsiao G et al. | Antiplatelet action of 3',4'-diisovalerylkhellactone diester purified from Peucedanum japonicum Thunb. | 1998 | Biol. Pharm. Bull. | pmid:9703250 |
| Durando MM et al. | Endotoxin activation of mitogen-activated protein kinase in THP-1 cells; diminished activation following endotoxin desensitization. | 1998 | J. Leukoc. Biol. | pmid:9715266 |
| Saareks V et al. | Nicotine stereoisomers and cotinine stimulate prostaglandin E2 but inhibit thromboxane B2 and leukotriene E4 synthesis in whole blood. | 1998 | Eur. J. Pharmacol. | pmid:9721044 |
| Takami M and Tsukada W | Correlative alteration of thromboxane A2 with antigen-induced bronchoconstriction and the role of platelets as a source of TXA2 synthesis in guinea pigs: effect of DP-1904, an inhibitor of thromboxane synthetase. | 1998 | Pharmacol. Res. | pmid:9721601 |
| Takami M and Tsukada W | In vitro effect of DP-1904, a novel anti-asthma agent, against antigen-induced constriction and TXB2 release from the isolated guinea-pig lung parenchymal tissue. | 1998 | Pharmacol. Res. | pmid:9721602 |
| Jain SK et al. | Relationship of blood thromboxane-B2 (TxB2) with lipid peroxides and effect of vitamin E and placebo supplementation on TxB2 and lipid peroxide levels in type 1 diabetic patients. | 1998 | Diabetes Care | pmid:9727900 |
| Roberts LJ et al. | Metabolism of thromboxane B2 in the monkey. | 1978 | J. Biol. Chem. | pmid:97291 |
| Gonchar MV et al. | Lack of direct connection between arachidonic acid release and prostanoid synthesis upon differentiation of U937 cell. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9731221 |
| Simon LS et al. | Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects. | 1998 | Arthritis Rheum. | pmid:9751091 |
| Gajdos M et al. | Effective long-term inhibition of thromboxane production but not of serotonin release in patients with coronary heart disease by 30 mg/d acetylsalicylic acid dosage. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9758203 |
| Oosaki R et al. | Correlation among urinary eosinophil protein X, leukotriene E4, and 11-dehydrothromboxane B2 in patients with spontaneous asthmatic attack. | 1998 | Clin. Exp. Allergy | pmid:9761018 |
| van Dijk AP et al. | Transdermal nicotine inhibits interleukin 2 synthesis by mononuclear cells derived from healthy volunteers. | 1998 | Eur. J. Clin. Invest. | pmid:9767362 |
| Yan DH et al. | [Study on experimental parameters for diagnosing ganyang huafeng syndrome of cerebral infarction]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9772617 |
| Brinkmann A et al. | Vasopressor hormone response following mesenteric traction during major abdominal surgery. | 1998 | Acta Anaesthesiol Scand | pmid:9773140 |
| Power I et al. | Effects of ketorolac and dextran-70 alone and in combination on haemostasis. | 1998 | Acta Anaesthesiol Scand | pmid:9773144 |
| Chavali SR et al. | Increased production of TNF-alpha and decreased levels of dienoic eicosanoids, IL-6 and IL-10 in mice fed menhaden oil and juniper oil diets in response to an intraperitoneal lethal dose of LPS. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9774171 |
| Chen MF et al. | Vitamin E supplementation attenuates myointimal proliferation of the abdominal aorta after balloon injury in diet-induced hypercholesterolemic rabbits. | 1998 | Prostaglandins Other Lipid Mediat. | pmid:9777654 |
| Lindström T et al. | The effect of unreamed and reamed intramedullary nailing on the urinary excretion of prostacyclin and thromboxane A2 metabolites in patients with tibial shaft fractures. | 1998 | J Trauma | pmid:9783614 |
| John H et al. | Development and review of radioimmunoassay of 12-S-hydroxyheptadecatrienoic acid. | 1998 | Prostaglandins Other Lipid Mediat. | pmid:9785378 |
| Thomson M et al. | Prostanoid synthesis in whole blood cells from fish of the Arabian Gulf. | 1998 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:9787758 |
| Smith CJ et al. | Pharmacological analysis of cyclooxygenase-1 in inflammation. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9789085 |
| Sheu JR et al. | Mechanisms involved in the antiplatelet activity of Escherichia coli lipopolysaccharide in human platelets. | 1998 | Br. J. Haematol. | pmid:9792285 |
| Obase Y et al. | Effects of cysteinyl-leukotriene receptor antagonist, thromboxane A2 receptor antagonist, and thromboxane A2 synthetase inhibitor on antigen-induced bronchoconstriction in patients with asthma. | 1998 | Chest | pmid:9792572 |
| Turpeinen AM et al. | Replacement of dietary saturated by unsaturated fatty acids: effects of platelet protein kinase C activity, urinary content of 2,3-dinor-TXB2 and in vitro platelet aggregation in healthy man. | 1998 | Thromb. Haemost. | pmid:9798986 |
| Huszár E et al. | Elevated circulating adenosine level potentiates antigen-induced immediate bronchospasm and bronchoconstrictor mediator release in sensitized guinea pigs. | 1998 | J. Allergy Clin. Immunol. | pmid:9802380 |
| Cullen L et al. | Selective cyclooxygenase-2 inhibition by nimesulide in man. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808683 |
| Hellyer PW et al. | The effects of hyperoxia on the biosynthesis of cyclooxygenase products and haemodynamic response to nitric oxide synthase inhibition with L-NAME in endotoxaemic pigs. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9811434 |
| Dobner P and Engelmann B | Low-density lipoproteins supply phospholipid-bound arachidonic acid for platelet eicosanoid production. | 1998 | Am. J. Physiol. | pmid:9814996 |
| Jiang XW et al. | Effects of low-dose Beraprost sodium, a stable prostaglandin I2 analogue, on reperfusion injury to rabbit lungs. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9817723 |
| Menè P et al. | Eicosanoid synthesis in peripheral blood monocytes: a marker of disease activity in lupus nephritis. | 1998 | Am. J. Kidney Dis. | pmid:9820447 |
| Saitta A et al. | Effects of picotamide on release of endothelin-1, thromboxane and prostacycline after treadmill stress in patients with peripheral artery disease. | 1998 | Angiology | pmid:9822043 |
| Hauth J et al. | Maternal serum thromboxane B2 concentrations do not predict improved outcomes in high-risk pregnancies in a low-dose aspirin trial. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medical Units. | 1998 | Am. J. Obstet. Gynecol. | pmid:9822499 |
| Kalgutkar AS et al. | Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators. | 1998 | J. Med. Chem. | pmid:9822550 |
| Schmeck J et al. | Endothelin-1 and thromboxane A2 increase pulmonary vascular resistance in granulocyte-mediated lung injury. | 1998 | Crit. Care Med. | pmid:9824081 |
| Henry A et al. | Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein. | 1998 | Br. J. Haematol. | pmid:9827912 |
| Ricketts AP et al. | Evaluation of selective inhibition of canine cyclooxygenase 1 and 2 by carprofen and other nonsteroidal anti-inflammatory drugs. | 1998 | Am. J. Vet. Res. | pmid:9829404 |
| Hayashi N et al. | Effects of intravenous omega-3 and omega-6 fat emulsion on cytokine production and delayed type hypersensitivity in burned rats receiving total parenteral nutrition. | 1998 Nov-Dec | JPEN J Parenter Enteral Nutr | pmid:9829609 |
| de la Cruz JP et al. | Effect of WEB 2086-BS, an antagonist of platelet-activating factor receptors, on retinal vascularity in diabetic rats. | 1998 | Eur. J. Pharmacol. | pmid:9845270 |
| Stadelmann WK et al. | Aprotinin in ischemia-reperfusion injury: flap survival and neutrophil response in a rat skin flap model. | 1998 | Microsurgery | pmid:9846997 |
| Praticò D et al. | Chronic obstructive pulmonary disease is associated with an increase in urinary levels of isoprostane F2alpha-III, an index of oxidant stress. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9847257 |
| Paarlberg KM et al. | Vasoactive mediators in pregnancy-induced hypertensive disorders: a longitudinal study. | 1998 | Am. J. Obstet. Gynecol. | pmid:9855596 |
| Sun ZT et al. | [Clinical and experimental study on treating bronchial asthma with xingbei granule]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863090 |
| Zhang XY and Qian XM | [Clinical study of sudden deafness treated with method of integrated traditional Chinese and Western medicine]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863112 |
| Wu JX et al. | [Effects and mechanism of emodin and sandostatin on pancreatic ischemia in acute haemorrhagic necrotizing pancreatitis]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863132 |
| Hu DH et al. | [Effects of hypoxia and anisodamine on products of TXA2 and PGI2 in cultured intra-pulmonary arteriolar smooth muscle cells]. | 1997 | Sheng Li Xue Bao | pmid:9863190 |
| Li HP et al. | [The relationship between the activity of phospholipase A2 and acute hypoxic pulmonary arterial pressure]. | 1997 | Sheng Li Xue Bao | pmid:9863193 |
| Hwang GS et al. | Effects of Brazilin on the phospholipase A2 activity and changes of intracellular free calcium concentration in rat platelets. | 1998 | Arch. Pharm. Res. | pmid:9868555 |
| McAdam BF et al. | Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9874808 |
| Takeuchi K et al. | Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition. 3. Synthesis and biological activities of oxazolecarboxamide-substituted omega-phenyl-omega-(3-pyridyl)alkenoic acid derivatives and related compounds. | 1998 | J. Med. Chem. | pmid:9876106 |
| Guimarães PC et al. | Variations in white blood count, thromboxane B2 levels and hematocrit in chronic venous hypertension. | 1998 May-Jun | Sao Paulo Med J | pmid:9876450 |
| Shen ZQ et al. | Effects of copper-aspirin complex on platelet aggregation and thrombosis in rabbits and mice. | 1998 | J. Pharm. Pharmacol. | pmid:9877314 |
| Hoffmann MW et al. | [Long term effects of 50 mg acetylsalicylic acid alone and in combination with dipyridamole on platelet function after coronary bypass surgery]. | 1998 | Z Kardiol | pmid:9885179 |
| González E et al. | Nitric oxide modulates placental prostanoid production from late pregnant non-insulin-dependent diabetic rat. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9888203 |
| Davì G et al. | In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation. | 1999 | Circulation | pmid:9892587 |
| Holt S et al. | Acute cholestasis-induced renal failure: effects of antioxidants and ligands for the thromboxane A2 receptor. | 1999 | Kidney Int. | pmid:9893136 |
| Huang YS et al. | Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns. | 1998 | Burns | pmid:9915670 |
| MacKay RJ et al. | Effect of a conjugate of polymyxin B-dextran 70 in horses with experimentally induced endotoxemia. | 1999 | Am. J. Vet. Res. | pmid:9918150 |
| Fredenrich A et al. | Effects of low density and high density lipoproteins isolated from non-insulin dependent diabetic patients on prostaglandin secretion by mouse macrophage cell line P388D1. | 1999 | Atherosclerosis | pmid:9920525 |
| Gust R et al. | Response to inhaled nitric oxide in acute lung injury depends on distribution of pulmonary blood flow prior to its administration. | 1999 | Am. J. Respir. Crit. Care Med. | pmid:9927374 |
| Montuschi P et al. | Anaphylaxis increases 8-iso-prostaglandin F2alpha release from guinea-pig lung in vitro. | 1999 | Eur. J. Pharmacol. | pmid:9988124 |
| Bode AP et al. | Activation and adherence of lyophilized human platelets on canine vessel strips in the Baumgartner perfusion chamber. | 1999 | J. Lab. Clin. Med. | pmid:9989772 |
| Hayashi N et al. | Effect of intravenous omega-6 and omega-3 fat emulsions on nitrogen retention and protein kinetics in burned rats. | 1999 | Nutrition | pmid:9990578 |