Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Takakuwa K et al. | Immunosuppressive therapy for recurrent aborters with positive antiphospholipid antibodies and alteration of 6ketoPGF1 alpha/TXB2 ratio. | 1997 | J Perinat Med | pmid:9494925 |
Turner NC et al. | Elevated renal endothelin-I clearance and mRNA levels associated with albuminuria and nephropathy in non-insulin-dependent diabetes mellitus: studies in obese fa/fa Zucker rats. | 1997 | Clin. Sci. | pmid:9497794 |
Bagdasarian A et al. | IVIG adverse reactions: potential role of cytokines and vasoactive substances. | 1998 | Vox Sang. | pmid:9501404 |
Bernareggi M et al. | Bronchopulmonary effects of 8-epi-PGF2A in anaesthetised guinea pigs. | 1998 | Pharmacol. Res. | pmid:9503483 |
Dschietzig T et al. | Coronary constriction and consequent cardiodepression in pulmonary embolism are mediated by pulmonary big endothelin and enhanced in early endothelial dysfunction. | 1998 | Crit. Care Med. | pmid:9504580 |
Schilling MK et al. | Role of thromboxane and leukotriene B4 in patients with acute respiratory distress syndrome after oesophagectomy. | 1998 | Br J Anaesth | pmid:9505775 |
Giardiello FM et al. | Prostaglandin levels in human colorectal mucosa: effects of sulindac in patients with familial adenomatous polyposis. | 1998 | Dig. Dis. Sci. | pmid:9512123 |
Larsen LN et al. | Alpha- and beta- alkyl-substituted eicosapentaenoic acids: incorporation into phospholipids and effects on prostaglandin H synthase and 5-lipoxygenase. | 1998 | Biochem. Pharmacol. | pmid:9514074 |
Rho MC et al. | Two distinct effects of 12S-hydroxyeicosatetraenoic acid on platelet aggregation by zooxanthellatoxin-A and ionomycin. | 1998 | Jpn. J. Pharmacol. | pmid:9517414 |
Giustina A et al. | Long-term treatment with the dual antithromboxane agent picotamide decreases microalbuminuria in normotensive type 2 diabetic patients. | 1998 | Diabetes | pmid:9519749 |
Bode-Böger SM et al. | Differential inhibition of human platelet aggregation and thromboxane A2 formation by L-arginine in vivo and in vitro. | 1998 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:9521487 |
Ooi BS et al. | Stimulation of endothelial cell production of vasoconstrictive substances by hypertensive sera. | 1998 | Am. J. Hypertens. | pmid:9524055 |
Bons-Sicard C et al. | Localization and quantification of TXB2 in human healthy and inflammatory gingival mucosa. | 1998 | J. Periodont. Res. | pmid:9524318 |
Diven WF et al. | Expression of acute otitis media after receptor blockade of platelet activating factor, thromboxane, and leukotrienes in the chinchilla. | 1998 | Ann. Otol. Rhinol. Laryngol. | pmid:9525240 |
Fukushima C et al. | Effect of synthetase inhibitors and receptor antagonists in antigen-induced contraction of human lung parenchyma. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9532973 |
Zhao Y et al. | Urinary thromboxane B2 in cardiac transplant patients as a screening method of rejection. | 1997 | Prostaglandins | pmid:9533183 |
Herrera JA et al. | Prevention of preeclampsia by linoleic acid and calcium supplementation: a randomized controlled trial. | 1998 | Obstet Gynecol | pmid:9540946 |
Liao CH et al. | Effect of PP1D-1, a synthetic antiplatelet compound, on rabbit platelets. | 1998 | Jpn. J. Pharmacol. | pmid:9541276 |
Suchkova V | Prostanoid and anti-thrombin III levels in premature infants. | 1997 | Adv. Exp. Med. Biol. | pmid:9547655 |
Kimura H et al. | Compensatory excretion of prostacyclin and thromboxane metabolites in obstructive sleep apnea syndrome. | 1998 | Intern. Med. | pmid:9550591 |