Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hamberg M et al. | A method for measurement of platelet regeneration in man. | 1978 | Prostaglandins Med | pmid:104315 |
McCowan LM et al. | Administration of low-dose aspirin to mothers with small for gestational age fetuses and abnormal umbilical Doppler studies to increase birthweight: a randomised double-blind controlled trial. | 1999 | Br J Obstet Gynaecol | pmid:10428519 |
Kawano K et al. | Superiority of platelet integrin GPIIb-IIIa receptor antagonist over aspirin in preventing cyclic flow reductions in the guinea pig middle cerebral artery. | 1999 | Eur. J. Pharmacol. | pmid:10422782 |
Mercer JB et al. | The effect of short-term cold exposure on risk factors for cardiovascular disease. | 1999 | Thromb. Res. | pmid:10418798 |
Morrow JD et al. | Increased formation of thromboxane in vivo in humans with mastocytosis. | 1999 | J. Invest. Dermatol. | pmid:10417625 |
Jönsson A et al. | Effects of amide local anaesthetics on eicosanoid formation in burned skin. | 1999 | Acta Anaesthesiol Scand | pmid:10408815 |
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Saareks V et al. | Nicotinic acid and pyridoxine modulate arachidonic acid metabolism in vitro and ex vivo in man. | 1999 | Pharmacol. Toxicol. | pmid:10401729 |
Peredo HA et al. | Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10397409 |
Bowers W et al. | Artificial human skin: cytokine, prostaglandin, Hsp70 and histological responses to heat exposure. | 1999 | J. Dermatol. Sci. | pmid:10397388 |