Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Seizures D012640 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Atherosclerosis D050197 85 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Stomach Ulcer D013276 75 associated lipids
Hyperlipidemias D006949 73 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Coronary Disease D003327 70 associated lipids
Colitis D003092 69 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Reperfusion Injury D015427 65 associated lipids
Pain D010146 64 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Weight Loss D015431 56 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Asthma D001249 52 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Thrombosis D013927 49 associated lipids
Fatty Liver D005234 48 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Lung Diseases D008171 37 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Heart Failure D006333 36 associated lipids
Glomerulonephritis D005921 35 associated lipids
Fever D005334 35 associated lipids
Anaphylaxis D000707 35 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Burns D002056 34 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Uremia D014511 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Stroke D020521 32 associated lipids
Proteinuria D011507 30 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Endometriosis D004715 29 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Endotoxemia D019446 27 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Angina Pectoris D000787 27 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Gastritis D005756 27 associated lipids
Nasal Polyps D009298 26 associated lipids
Ascites D001201 25 associated lipids
Hyperemia D006940 25 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Cattle Diseases D002418 24 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Pulmonary Edema D011654 23 associated lipids
Birth Weight D001724 23 associated lipids
Fibrosis D005355 23 associated lipids
Hypoxia D000860 23 associated lipids
Hypersensitivity D006967 22 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Anemia D000740 21 associated lipids
Myocardial Infarction D009203 21 associated lipids
Helicobacter Infections D016481 21 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Wounds and Injuries D014947 20 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Pleurisy D010998 20 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Peptic Ulcer D010437 19 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Nephritis D009393 19 associated lipids
Cough D003371 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Stuart MJ et al. The influence of albumin and calcium on human platelet arachidonic acid metabolism. 1980 Blood pmid:6766753
Patrono C et al. Radioimmunoassay measurement of stable metabolites of platelet arachidonic acid: a convenient method for the in vitro and ex vivo evaluation of cyclo-oxygenase inhibitors. 1980 Agents Actions Suppl. pmid:6787852
Vargaftig BB et al. Activation of guinea-pig platelets induced by convulxin, a substance extracted from the venom of Crotalus durissus cascavella. 1980 Eur. J. Pharmacol. pmid:7009169
Giri SN and Krishna GA Development of a dual isotopes techniques and two-stage column chromatography to characterize the prostaglandin F2alpha, E2 and Thromboxane B2 formed by the guinea pig lung. 1980 J Pharmacol Methods pmid:7009992
Heggers JP et al. Evaluation of burn blister fluid. 1980 Plast. Reconstr. Surg. pmid:6770396
Wise WC et al. Protective effects of thromboxane synthetase inhibitors in rats in endotoxic shock. 1980 Circ. Res. pmid:7189697
Mathé AA et al. Increased content of immunoreactive prostaglandin E in cerebrospinal fluid of patients with schizophrenia. 1980 Lancet pmid:6101355
Mestel F et al. Severe bleeding associated with defective thromboxane synthetase. 1980 Lancet pmid:6101498
Pareti FI et al. Platelets and the vessel wall: how much aspirin? 1980 Lancet pmid:6101829
Sanger GJ and Bennett A Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. 1980 Adv Prostaglandin Thromboxane Res pmid:6103666
Zahavi J et al. Enhanced in-vivo platelet release reaction, increased thromboxane synthesis, and decreased prostacyclin release after tourniquet ischaemia. 1980 Lancet pmid:6106784
Tada M et al. Significance of thromboxane A2 in myocardial ischemia in patients with coronary artery disease. 1980 Adv Myocardiol pmid:7423053
Matsumoto M et al. Thromboxane generation in patients with essential hypertension or cerebrovascular disease and effect of oral aspirin. 1980 Thromb. Haemost. pmid:7423441
Kennedy MS et al. In vitro synthesis of prostaglandins and related lipids by populations of human peripheral blood mononuclear cells. 1980 Prostaglandins pmid:6967616
Galli C et al. Modulation of prostaglandin production in tissues by dietary essential fatty acids. 1980 Acta Med. Scand. Suppl. pmid:6935943
Wong PY et al. The role of calmodulin in prostaglandin metabolism. 1980 Ann. N. Y. Acad. Sci. pmid:6940495
Lefer AM and Crossley K Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia. 1980 Adv Shock Res pmid:7304314
Schlondorff D and Folkert VW Prostaglandin synthesis in glomeruli from rats with unilateral ureteral obstruction. 1980 Adv Prostaglandin Thromboxane Res pmid:7369028
Van Praag D and Farber SJ Prostaglandin biosynthesis in normal and ureteral obstructed rabbit kidney; formation of a novel metabolite. 1980 Adv Prostaglandin Thromboxane Res pmid:7369029
Lindgren JA et al. Effects of platelet aggregation and adenosine 3':5'-monophosphate on the synthesis of thromboxane B2 in human platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:6247886
Kot PA et al. Modification of the cardiovascular actions of prostaglandins by thromboxane B2. 1980 Adv Prostaglandin Thromboxane Res pmid:7369035
Gorman RR Biochemical and pharmacological evaluation of thromboxane synthetase inhibitors. 1980 Adv Prostaglandin Thromboxane Res pmid:6247892
Friedman LS et al. Thromboxane B2 inhibits the pulmonary metabolism of PGE2 in the anesthetized dog. 1980 Adv Prostaglandin Thromboxane Res pmid:7369063
Garfield RE et al. Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. 1980 Am. J. Physiol. pmid:7369350
Lewy RI Effect of elevated plasma-free fatty acids on thromboxane release in patients with coronary artery disease. 1980 Haemostasis pmid:7372200
Bishai I and Coceani F Metabolism of PGH2 in the feline brain. 1980 Adv Prostaglandin Thromboxane Res pmid:7376980
Galli C et al. Factors affecting brain prostaglandin formation. 1980 Adv Prostaglandin Thromboxane Res pmid:7376983
Blotman F et al. PGE2, PGF2 alpha, and TXB2 biosynthesis by human rheumatoid synovia. 1980 Adv Prostaglandin Thromboxane Res pmid:7377017
Maclouf J et al. Interactions of prostaglandin H2 and thromboxane A2 with human serum albumin. 1980 Eur. J. Biochem. pmid:7408901
Hwang DW et al. Species variation in serum levels of prostaglandins and their precursor acids. 1980 Lipids pmid:7432104
Lewy RI et al. Thromboxane release during pacing-induced angina pectoris: possible vasoconstrictor influence on the coronary vasculature. 1980 Circulation pmid:7371128
McManus LM et al. Thromboxane B2 (TxB2) release during IgE anaphylaxis in the rabbit. 1980 J. Immunol. pmid:7430618
Meyers KM et al. An evaluation of the arachidonate pathway of platelets from companion and food-producing animals, mink, and man. 1980 Thromb. Res. pmid:7209869
Kosaki G et al. The mechanism of the inhibitory effect of protease inhibitors on platelet aggregation and cellular synthesis of prostaglandins. I. The effect on the release of arachidonic acid from phospholipids. 1980 Dec 1-15 Thromb. Res. pmid:6785893
Patrono C et al. Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. 1980 Feb 1-15 Thromb. Res. pmid:7368167
Koh H et al. A radioimmunoassay of thromboxane B2 with thromboxane B2-125I-tyramide and its application to the study on the thromboxane B2 formation during platelet aggregation. 1980 Feb 1-15 Thromb. Res. pmid:7368170
Boyd JA and Eling TE Prostaglandin release and the interaction of platelets with the pulmonary vasculature of rat and guinea pig. 1980 Jul 1-15 Thromb. Res. pmid:7003800
Singh D et al. Evidence for the generation of hydroxyl radical during arachidonic acid metabolism by human platelets. 1981 Am. J. Hematol. pmid:6274189
Nordøy A Lipids and thrombogenesis. 1981 Ann. Clin. Res. pmid:7018362
Baroody RA and Bito LZ The impermeability of the basic cell membrane to thromboxane-B2' prostacyclin and 6-keto-PGF 1 alpha. 1981 Prostaglandins pmid:7010455
Chong BH et al. Heparin-induced thrombocytopenia: effect of heparin platelet antibody on platelets. 1981 Br. J. Haematol. pmid:7317283
Gordon D et al. Selective inhibition of thromboxane biosynthesis in human blood mononuclear cells and the effects of mitogen-stimulated lymphocyte proliferation. 1981 Br. J. Pharmacol. pmid:7317694
Satoh K et al. Augmented malondialdehyde production by platelets from patients with cerebrovascular disorders. 1981 Jpn. Circ. J. pmid:7321143
Catalano PM et al. Platelet recovery from aspirin inhibition in vivo; differing patterns under various assay conditions. 1981 Blood pmid:7448419
Laviolette M et al. Human alveolar macrophages: a lesion in arachidonic acid metabolism in cigarette smokers. 1981 Am. Rev. Respir. Dis. pmid:6794395
Corby DG and O'Barr TP Neonatal platelet function: a membrane-related phenomenon? 1981 Haemostasis pmid:7250785
Wonders TR et al. Reduced plasma thromboxane elevation during partial cardiopulmonary bypass in thrombocytopenic sheep. 1981 Trans Am Soc Artif Intern Organs pmid:7331082
Landgraf-Leurs MM et al. Aggregation and thromboxane B2 formation in platelets and vascular prostacyclin production from genetically obese rats. 1981 Prostaglandins pmid:6798637
Brox JH et al. The effect of cod liver oil and corn oil on platelets and vessel wall in man. 1981 Thromb. Haemost. pmid:7031981
Hirsh PD et al. Prostaglandins and ischemic heart disease. 1981 Am. J. Med. pmid:7032286