Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Abortion, Habitual D000026 5 associated lipids
Acidosis D000138 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Agranulocytosis D000380 7 associated lipids
Airway Obstruction D000402 13 associated lipids
Albuminuria D000419 18 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Anaphylaxis D000707 35 associated lipids
Anemia D000740 21 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Angina, Unstable D000789 14 associated lipids
Hypoxia D000860 23 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Aortic Rupture D001019 3 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Arthus Reaction D001183 8 associated lipids
Ascites D001201 25 associated lipids
Asthenia D001247 5 associated lipids
Asthma D001249 52 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Bartter Syndrome D001477 5 associated lipids
Behcet Syndrome D001528 7 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Birth Weight D001724 23 associated lipids
Blister D001768 16 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Bluetongue D001819 1 associated lipids
Body Weight D001835 333 associated lipids
Bronchial Spasm D001986 18 associated lipids
Bronchitis D001991 6 associated lipids
Bronchopneumonia D001996 7 associated lipids
Bronchopulmonary Dysplasia D001997 4 associated lipids
Bronchopulmonary Sequestration D001998 3 associated lipids
Burns D002056 34 associated lipids
Byssinosis D002095 11 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cat Diseases D002371 12 associated lipids
Cattle Diseases D002418 24 associated lipids
Celiac Disease D002446 16 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Intracranial Embolism and Thrombosis D002542 5 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Chest Pain D002637 4 associated lipids
Choline Deficiency D002796 16 associated lipids
Cleft Palate D002972 9 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Contusions D003288 3 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Coronary Disease D003327 70 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Cough D003371 19 associated lipids
Death, Sudden D003645 12 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diseases in Twins D004200 4 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Drowning D004332 2 associated lipids
Ductus Arteriosus, Patent D004374 5 associated lipids
Edema D004487 152 associated lipids
Edema, Cardiac D004489 1 associated lipids
Embolism, Fat D004620 4 associated lipids
Endometriosis D004715 29 associated lipids
Enteritis D004751 8 associated lipids
Erythromelalgia D004916 1 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Eye Burns D005126 13 associated lipids
Facial Pain D005157 5 associated lipids
Fatty Liver D005234 48 associated lipids
Femoral Fractures D005264 7 associated lipids
Fetal Diseases D005315 8 associated lipids
Fever D005334 35 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Fibrosis D005355 23 associated lipids
Fistula D005402 8 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Clark KE et al. Effect of bisenoic prostaglandins and arachidonic acid on the uterine vasculature of pregnant sheep. 1982 Am. J. Obstet. Gynecol. pmid:7065014
van der Weiden RM et al. Prostanoid excretion in incipient singleton and twin pregnancies. 1996 Am. J. Obstet. Gynecol. pmid:9065139
Presser SC et al. Simultaneous measurements of prostacyclin and thromboxane metabolites during the menstrual cycle. 1991 Am. J. Obstet. Gynecol. pmid:1892191
Fantone JC et al. Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. 1984 Am. J. Pathol. pmid:6324595
Cybulsky AV et al. A role for thromboxane in complement-mediated glomerular injury. 1987 Am. J. Pathol. pmid:3111267
Zoja C et al. Selective inhibition of platelet thromboxane generation with low-dose aspirin does not protect rats with reduced renal mass from the development of progressive disease. 1989 Am. J. Pathol. pmid:2497648
Lundberg C et al. C5a-induced hemodynamic and hematologic changes in the rabbit. Role of cyclooxygenase products and polymorphonuclear leukocytes. 1987 Am. J. Pathol. pmid:3115110
Stimler NP and O'Flaherty JT Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues. 1983 Am. J. Pathol. pmid:6624879
Woods LW et al. Structural and biochemical changes in lungs of 3-methylindole-treated rats. 1993 Am. J. Pathol. pmid:8424451
Diamond JR et al. Altered functional characteristics of rat macrophages during nephrosis. Synergistic effects of hypercholesterolemia. 1989 Am. J. Pathol. pmid:2801885
Cook HT et al. Functional characteristics of macrophages in glomerulonephritis in the rat. O2- generation, MHC class II expression, and eicosanoid synthesis. 1989 Am. J. Pathol. pmid:2537019
Mundie TG et al. Byssinosis: Release of prostaglandins, thromboxane, and 5-hydroxytryptamine in bronchopulmonary lavage fluid after inhalation of cotton dust extracts. 1985 Am. J. Pathol. pmid:3966532
Bertani T et al. Tumor necrosis factor induces glomerular damage in the rabbit. 1989 Am. J. Pathol. pmid:2916653
Hamilton J et al. Platelet interaction with a pancreatic ascites tumor. 1986 Am. J. Pathol. pmid:3510553
Nanji AA et al. Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2. 1993 Am. J. Pathol. pmid:8382006
Nath KA et al. Regulatory role of prostanoids in glomerular microcirculation of remnant nephrons. 1987 Am. J. Physiol. pmid:3578532
Yamamoto S et al. Endothelin causes portal and pulmonary hypertension in porcine endotoxemic shock. 1997 Am. J. Physiol. pmid:9087598
Krausz MM et al. Adverse effects of prostacyclin used to perfuse isolated lung lobes. 1982 Am. J. Physiol. pmid:7044149
Düsing R et al. Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. 1983 Am. J. Physiol. pmid:6337507
Wilkes BM and Mento PF Bradykinin-induced vasoconstriction and thromboxane release in perfused human placenta. 1988 Am. J. Physiol. pmid:3377072
Abernathy VJ et al. C-reactive protein inhibits increased pulmonary vascular permeability induced by fMLP in isolated rabbit lungs. 1996 Am. J. Physiol. pmid:8770090
Closa D et al. Hepatic involvement in pancreatitis-induced lung damage. 1996 Am. J. Physiol. pmid:8772495
Strand JC et al. Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. 1981 Am. J. Physiol. pmid:6787931
Katusić ZS et al. Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery. 1993 Am. J. Physiol. pmid:8456988
Simonson MS et al. Identification and transmembrane signaling of leukotriene D4 receptors in human mesangial cells. 1988 Am. J. Physiol. pmid:2849305
Toyofuku T et al. Pulmonary vascular response to platelet-activating factor in conscious sheep. 1988 Am. J. Physiol. pmid:3414811
Widdicombe JH et al. Release of cyclooxygenase products from primary cultures of tracheal epithelia of dog and human. 1989 Am. J. Physiol. pmid:2514604
Zipser RD and Martin K Urinary excretion of arterial blood prostaglandins and thromboxanes in man. 1982 Am. J. Physiol. pmid:6950668
Vanderhoof JA et al. Reduced mucosal prostaglandin synthesis after massive small bowel resection. 1988 Am. J. Physiol. pmid:3279815
Amsterdam EA et al. Contractile actions of C5a on isolated porcine myocardium. 1992 Am. J. Physiol. pmid:1357981
Utsunomiya T et al. Modification of inflammatory response to aspiration with ibuprofen. 1982 Am. J. Physiol. pmid:6756172
Dobner P and Engelmann B Low-density lipoproteins supply phospholipid-bound arachidonic acid for platelet eicosanoid production. 1998 Am. J. Physiol. pmid:9814996
Coceani F et al. Further evidence implicating prostaglandin E2 in the genesis of pyrogen fever. 1988 Am. J. Physiol. pmid:3279826
Del Maschio A et al. Platelet activation by polymorphonuclear leukocytes exposed to chemotactic agents. 1990 Am. J. Physiol. pmid:2156456
Stephenson AH et al. 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. 1998 Am. J. Physiol. pmid:9688901
Kruse-Elliott KT and Olson NC CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. 1993 Am. J. Physiol. pmid:8386479
Greenberg S et al. Pulmonary vascular smooth muscle function in porcine splanchnic arterial occlusion shock. 1981 Am. J. Physiol. pmid:7246787
Perlman MB et al. Ibuprofen prevents thrombin-induced lung vascular injury: mechanism of effect. 1987 Am. J. Physiol. pmid:3030141
Schlondorff D and Satriano JA Interactions of vasopressin, cAMP, and prostaglandins in toad urinary bladder. 1985 Am. J. Physiol. pmid:2579584
Barnard JW et al. Sustained effects of endothelin-1 on rabbit, dog, and rat pulmonary circulations. 1991 Am. J. Physiol. pmid:1877674
Stahl RA et al. Glomerular prostaglandin formation in two-kidney, one-clip hypertensive rats. 1984 Am. J. Physiol. pmid:6507633
Stenmark KR et al. Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension. 1985 Am. J. Physiol. pmid:3923843
Scharschmidt LA et al. Angiotensin II and eicosanoids in the control of glomerular size in the rat and human. 1986 Am. J. Physiol. pmid:2936254
Adler S et al. Biphasic effect of oxygen radicals on prostaglandin production by rat mesangial cells. 1987 Am. J. Physiol. pmid:3105332
Cudd TA and Wood CE Thromboxane A2 receptor antagonism prevents hormonal and cardiovascular responses to mineral acid infusion. 1994 Am. J. Physiol. pmid:7977850
Leffler CW and Busija DW Prostanoids and pial arteriolar diameter in hypotensive newborn pigs. 1987 Am. J. Physiol. pmid:3551632
Wagerle LC et al. Effect of dexamethasone on cerebral prostanoid formation and pial arteriolar reactivity to CO2 in newborn pigs. 1991 Am. J. Physiol. pmid:1901460
Benigni A et al. Renal metabolism and urinary excretion of thromboxane B2 in the rat. 1989 Am. J. Physiol. pmid:2750927
Del Balzo U et al. Complement C5a-mediated myocardial ischemia and neutrophil sequestration: two independent phenomena. 1993 Am. J. Physiol. pmid:8447449
Titos E et al. Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). 1999 Am. J. Physiol. pmid:10564079
Klausner JM et al. Postischemic renal injury is mediated by neutrophils and leukotrienes. 1989 Am. J. Physiol. pmid:2541628
Takashio T et al. Inhibitory effect of pindolol on hypoxic pulmonary vasoconstriction. 1992 Am. J. Physiol. pmid:1310232
Schrör K et al. Preservation of ischemic myocardium by pinane thromboxane A2. 1980 Am. J. Physiol. pmid:7356037
Sata T et al. Paraquat-induced lung injury: prevention by N-tert-butyl-alpha-phenylnitrone, a free-radical spin-trapping agent. 1992 Am. J. Physiol. pmid:1311515
Chakraborti S et al. Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium. 1989 Am. J. Physiol. pmid:2514605
Hollenberg SM et al. Eicosanoid production by human aortic endothelial cells in response to endothelin. 1994 Am. J. Physiol. pmid:7810729
McGowan HM et al. Dexamethasone attenuates reversal of hypertension in one-kidney, one-clip rats. 1988 Am. J. Physiol. pmid:3177664
Garfield RE et al. Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. 1980 Am. J. Physiol. pmid:7369350
Lampugnani MG and de Gaetano G Effects of metabolized and unmetabolized arachidonate on rat platelet shape change. 1984 Am. J. Physiol. pmid:6433724
Ahlquist DA et al. Factors influencing metabolism of arachidonic acid in guinea pig gastric mucosa. 1983 Am. J. Physiol. pmid:6401937
Whinnery MA et al. Thromboxane B2 and prostaglandin E2 in the rat kidney with unilateral ureteral obstruction. 1982 Am. J. Physiol. pmid:6950670
Murray MJ et al. Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs. 1995 Am. J. Physiol. pmid:8594921
Wilkes BM et al. Characterization of glomerular thromboxane receptor sites in the rat. 1989 Am. J. Physiol. pmid:2525345
Townsley MI et al. Pulmonary embolism: analysis of endothelial pore sizes in canine lung. 1988 Am. J. Physiol. pmid:3189571
Nukina S et al. Glycogenolytic effect of adenosine involves ATP from hepatocytes and eicosanoids from Kupffer cells. 1994 Am. J. Physiol. pmid:8304463
Grimminger F et al. Differential influence of arachidonic vs. eicosapentaenoic acid on experimental pulmonary hypertension. 1995 Am. J. Physiol. pmid:7611475
Kalichman MW et al. Effects of cocaine on blood flow and prostaglandin metabolites in rat sciatic nerve. 1994 Am. J. Physiol. pmid:8024013
Reyes AA and Klahr S Bladder contributes to eicosanoids excreted in urine. 1990 Am. J. Physiol. pmid:2240235
Teitelbaum I et al. Effect of cAMP on prostaglandin E2 production in cultured rat inner medullary collecting tubule cells. 1986 Am. J. Physiol. pmid:3020997
Klotman PE et al. Thromboxane synthetase inhibition improves function of hydronephrotic rat kidneys. 1986 Am. J. Physiol. pmid:3456211
Geisel J et al. Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2. 1994 Am. J. Physiol. pmid:7943269
Chen L et al. Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. 1997 Am. J. Physiol. pmid:9362253
Wilkes BM et al. Endothelin receptors in human placenta: relationship to vascular resistance and thromboxane release. 1990 Am. J. Physiol. pmid:2159236
Martin SE et al. Neuropeptide Y and coronary vasoconstriction: role of thromboxane A2. 1992 Am. J. Physiol. pmid:1415751
Beck N and Shaw JO Thromboxane B2 and prostaglandin E2 in the K+-depleted rat kidney. 1981 Am. J. Physiol. pmid:7468800
Don BR et al. Dietary protein intake modulates glomerular eicosanoid production in the rat. 1989 Am. J. Physiol. pmid:2539749
Reinke M Monitoring thromboxane in body fluids: a specific ELISA for 11-dehydrothromboxane B2 using a monoclonal antibody. 1992 Am. J. Physiol. pmid:1590375
Cohen RA et al. 5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries. 1983 Am. J. Physiol. pmid:6660308
Podjarny E et al. Prostanoids in renal failure induced by converting enzyme inhibition in sodium-depleted rats. 1988 Am. J. Physiol. pmid:3162354
Savla U et al. Cyclic stretch of airway epithelium inhibits prostanoid synthesis. 1997 Am. J. Physiol. pmid:9374729
Addonizio VP et al. Effects of verapamil and diltiazem on human platelet function. 1986 Am. J. Physiol. pmid:3006516
Havill AM et al. alpha-Naphthylthiourea produces dose-dependent lung vascular injury in sheep. 1982 Am. J. Physiol. pmid:6812437
Gyenes M and De Groot H Prostanoid release by Kupffer cells upon hypoxia-reoxygenation: role of pHi and Cai2+. 1993 Am. J. Physiol. pmid:8384798
Brown GP and Venuto RC In vitro renal eicosanoid production during pregnancy in rabbits. 1988 Am. J. Physiol. pmid:3287949
Perico N et al. Functional significance of exaggerated renal thromboxane A2 synthesis induced by cyclosporin A. 1986 Am. J. Physiol. pmid:3094383
Burch RM and Halushka PV Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells. 1982 Am. J. Physiol. pmid:6816073
Goldman G et al. Intravascular chemoattractants inhibit diapedesis by selective receptor occupancy. 1991 Am. J. Physiol. pmid:1847598
Bradley LM et al. Circulatory effects of PAF-acether in newborn piglets. 1989 Am. J. Physiol. pmid:2912183
Prosdocimi M et al. Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog. 1985 Am. J. Physiol. pmid:3838623
Zipser RD Effects of selective inhibition of thromboxane synthesis on renal function in humans. 1985 Am. J. Physiol. pmid:3839111
Fletcher MP et al. C5a-induced myocardial ischemia: role for CD18-dependent PMN localization and PMN-platelet interactions. 1993 Am. J. Physiol. pmid:7902015
Toda N et al. Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries. 1992 Am. J. Physiol. pmid:1558175
Kauser K and Rubanyi GM Gender difference in bioassayable endothelium-derived nitric oxide from isolated rat aortae. 1994 Am. J. Physiol. pmid:7810731
Sirko S et al. Prostaglandin formation in the hypothalamus in vivo: effect of pyrogens. 1989 Am. J. Physiol. pmid:2784289
Farman N et al. PGE2, PGF2 alpha, 6-keto-PGF1 alpha, and TxB2 synthesis along the rabbit nephron. 1987 Am. J. Physiol. pmid:3101513
Miller MJ et al. SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis. 1988 Am. J. Physiol. pmid:2847541
Brown GP and Venuto RC Eicosanoid production in rabbit vascular tissues and placentas. 1990 Am. J. Physiol. pmid:2316640
Ito BR and Del Balzo U Effect of platelet depletion and inhibition of platelet cyclooxygenase on C5a-mediated myocardial ischemia. 1994 Am. J. Physiol. pmid:7943373
Jones SA et al. Eicosanoids in third ventricular cerebrospinal fluid of fetal and newborn sheep. 1993 Am. J. Physiol. pmid:8381613
Miyazaki Y et al. Selective turnover of sarcolemmal phospholipids with lethal cardiac myocyte injury. 1990 Am. J. Physiol. pmid:2382705