Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Acute Kidney Injury D058186 34 associated lipids
Airway Remodeling D056151 3 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Atherosclerosis D050197 85 associated lipids
Dyslipidemias D050171 7 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Coronary Stenosis D023921 6 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Stroke D020521 32 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Venous Thrombosis D020246 11 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Thrombophilia D019851 6 associated lipids
Endotoxemia D019446 27 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Sepsis D018805 11 associated lipids
Systemic Inflammatory Response Syndrome D018746 4 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Osteoblastoma D018215 1 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
beta-Thalassemia D017086 5 associated lipids
Carotid Stenosis D016893 15 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Yang Deficiency D016711 3 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Helicobacter Infections D016481 21 associated lipids
Bacteremia D016470 9 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Reperfusion Injury D015427 65 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Wounds and Injuries D014947 20 associated lipids
Weil Disease D014895 2 associated lipids
Granulomatosis with Polyangiitis D014890 5 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Vascular Diseases D014652 16 associated lipids
Varicose Veins D014648 7 associated lipids
Uveitis D014605 14 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Uremia D014511 33 associated lipids
Ulcer D014456 16 associated lipids
Tooth, Impacted D014095 9 associated lipids
Thrombosis D013927 49 associated lipids
Thromboembolism D013923 6 associated lipids
Thrombocytopenia D013921 15 associated lipids
Thrombocythemia, Essential D013920 9 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Thrombasthenia D013915 4 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia D013610 7 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Streptococcal Infections D013290 4 associated lipids
Stomach Volvulus D013277 1 associated lipids
Stomach Ulcer D013276 75 associated lipids
Gastric Dilatation D013271 1 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Sneezing D012912 6 associated lipids
Shock, Septic D012772 11 associated lipids
Shock D012769 11 associated lipids
Seizures D012640 87 associated lipids
Sclerosis D012598 5 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Rhinitis D012220 10 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Retinal Diseases D012164 4 associated lipids
Retinal Detachment D012163 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Respiration Disorders D012120 5 associated lipids
Renal Artery Obstruction D012078 8 associated lipids
Raynaud Disease D011928 7 associated lipids
Radiculopathy D011843 1 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Pulmonary Edema D011654 23 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Kraayenbrink AA et al. Endothelial vasoactive mediators in preeclampsia. 1993 Am. J. Obstet. Gynecol. pmid:8333445
Clark KE et al. Effect of bisenoic prostaglandins and arachidonic acid on the uterine vasculature of pregnant sheep. 1982 Am. J. Obstet. Gynecol. pmid:7065014
Chavarría ME et al. Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia. 2003 Am. J. Obstet. Gynecol. pmid:12712098
Magness RR et al. Angiotensin II metabolic clearance rate and pressor responses in nonpregnant and pregnant women. 1994 Am. J. Obstet. Gynecol. pmid:8092213
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Markham SM et al. The effect of the menstrual cycle and of decompression stress on arachidonic acid-induced platelet aggregation and on intrinsic platelet thromboxane production in women compared with men. 1991 Am. J. Obstet. Gynecol. pmid:1750481
Walsh SW Preeclampsia: an imbalance in placental prostacyclin and thromboxane production. 1985 Am. J. Obstet. Gynecol. pmid:3923838
Chacho KJ et al. Peritoneal fluid in patients with and without endometriosis: prostanoids and macrophages and their effect on the spermatozoa penetration assay. 1986 Am. J. Obstet. Gynecol. pmid:2940869
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Drake TS et al. Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis. 1981 Am. J. Obstet. Gynecol. pmid:6894667
Ylikorkala O et al. Maternal prostacyclin, thromboxane, and placental blood flow. 1983 Am. J. Obstet. Gynecol. pmid:6338724
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Ylikorkala O et al. Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies. 1981 Am. J. Obstet. Gynecol. pmid:6895277
Fitzgerald DJ et al. Increased thromboxane biosynthesis in normal pregnancy is mainly derived from platelets. 1987 Am. J. Obstet. Gynecol. pmid:3618681
Nelson DM et al. Hypoxia limits differentiation and up-regulates expression and activity of prostaglandin H synthase 2 in cultured trophoblast from term human placenta. 1999 Am. J. Obstet. Gynecol. pmid:10203658
Walsh SW et al. Peroxide induces vasoconstriction in the human placenta by stimulating thromboxane. 1993 Am. J. Obstet. Gynecol. pmid:8238110
Moutquin JM et al. Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study. 1997 Am. J. Obstet. Gynecol. pmid:9423755
Maher JE et al. The effect of low-dose aspirin on fetal urine output and amniotic fluid volume. 1993 Am. J. Obstet. Gynecol. pmid:8238144
Owen J et al. The effect of low-dose aspirin on umbilical artery Doppler measurements. 1993 Am. J. Obstet. Gynecol. pmid:8238148
DuBard MB et al. Are pill counts valid measures of compliance in clinical obstetric trials? 1993 Am. J. Obstet. Gynecol. pmid:8238182
Glance DG et al. Prostaglandin production and stimulation by angiotensin II in the isolated perfused human placental cotyledon. 1985 Am. J. Obstet. Gynecol. pmid:3855602
van der Weiden RM et al. Prostanoid excretion in incipient singleton and twin pregnancies. 1996 Am. J. Obstet. Gynecol. pmid:9065139
Bergman A et al. The role of prostaglandins in detrusor instability. 1991 Am. J. Obstet. Gynecol. pmid:1750483
Spitz B et al. Low-dose aspirin. I. Effect on angiotensin II pressor responses and blood prostaglandin concentrations in pregnant women sensitive to angiotensin II. 1988 Am. J. Obstet. Gynecol. pmid:3189434
Miller KW and Keith JC Erythrocyte morphologic features and serum chemistry studies in ovine pregnancy-induced hypertension treated with thromboxane synthetase inhibitors. 1988 Am. J. Obstet. Gynecol. pmid:3189458
Peaceman AM and Rehnberg KA The effect of aspirin and indomethacin on prostacyclin and thromboxane production by placental tissue incubated with immunoglobulin G fractions from patients with lupus anticoagulant. 1995 Am. J. Obstet. Gynecol. pmid:7503174
Jouppila P et al. Ritodrine infusion during late pregnancy: effects on fetal and placental blood flow, prostacyclin, and thromboxane. 1985 Am. J. Obstet. Gynecol. pmid:3885740
Ylikorkala O and Mäkilä UM Prostacyclin and thromboxane in gynecology and obstetrics. 1985 Am. J. Obstet. Gynecol. pmid:3890549
Capponi A et al. Indomethacin modifies the fetal hemodynamic response induced by percutaneous umbilical blood sampling. 1997 Am. J. Obstet. Gynecol. pmid:9369815
Sørensen JD et al. Effects of fish oil supplementation in the third trimester of pregnancy on prostacyclin and thromboxane production. 1993 Am. J. Obstet. Gynecol. pmid:8456902
Diss EM et al. Study of thromboxane and prostacyclin metabolism in an in vitro model of first-trimester human trophoblast. 1992 Am. J. Obstet. Gynecol. pmid:1415390
Romero R et al. The relationship between spontaneous rupture of membranes, labor, and microbial invasion of the amniotic cavity and amniotic fluid concentrations of prostaglandins and thromboxane B2 in term pregnancy. 1993 Am. J. Obstet. Gynecol. pmid:8317506
Cervar M et al. Drug actions in preeclampsia: aspirin, but not magnesium chloride or dihydralazine, differentially inhibits cultured human trophoblast release of thromboxane and prostacyclin without affecting angiotensin II, endothelin-1, or leukotriene B4 secretion. 1997 Am. J. Obstet. Gynecol. pmid:9024091
Kurki T et al. Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin. 1992 Am. J. Obstet. Gynecol. pmid:1733190
Presser SC et al. Simultaneous measurements of prostacyclin and thromboxane metabolites during the menstrual cycle. 1991 Am. J. Obstet. Gynecol. pmid:1892191
Johnson RD et al. Aspirin induces increased expression of both prostaglandin H synthase-1 and prostaglandin H synthase-2 in cultured human placental trophoblast. 1997 Am. J. Obstet. Gynecol. pmid:9240586
Monga M et al. Cocaine alters placental production of thromboxane and prostacyclin. 1994 Am. J. Obstet. Gynecol. pmid:7943110
Thorp JA et al. Low-dose aspirin inhibits thromboxane, but not prostacyclin, production by human placental arteries. 1988 Am. J. Obstet. Gynecol. pmid:3061295
Kang IS et al. Dose-related action of gonadotropin-releasing hormone on basal prostanoid production from the human term placenta. 1991 Am. J. Obstet. Gynecol. pmid:1750474
Rouse DJ et al. Midpregnancy serum thromboxane B2 determinations do not predict subsequent adverse pregnancy outcomes. 1993 Am. J. Obstet. Gynecol. pmid:8333431
Ylikorkala O et al. The effect of oral contraceptives on antiaggregatory prostacyclin and proaggregatory thromboxane A2 in humans. 1982 Am. J. Obstet. Gynecol. pmid:7036746