Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kranzhofer R and Ruef J | Aspirin resistance in coronary artery disease is correlated to elevated markers for oxidative stress but not to the expression of cyclooxygenase (COX) 1/2, a novel COX-1 polymorphism or the PlA(1/2) polymorphism. | 2006 | Platelets | pmid:16702043 |
| Chen GG et al. | Increased thromboxane B(2) levels are associated with lipid peroxidation and Bcl-2 expression in human lung carcinoma. | 2006 | Cancer Lett. | pmid:15876485 |
| Sailaja Devi MM and Das UN | Effect of prostaglandins against alloxan-induced diabetes mellitus. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16297610 |
| Zhou Y et al. | Increased expression of cyclooxygenase-2 mediates enhanced contraction to endothelin ETA receptor stimulation in endothelial nitric oxide synthase knockout mice. | 2006 | Circ. Res. | pmid:16645140 |
| Wilder-Smith CH et al. | Dose-effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects. | 2006 | Scand. J. Gastroenterol. | pmid:16497612 |
| Brenneis C et al. | Inhibition of prostaglandin E2 synthesis by SC-560 is independent of cyclooxygenase 1 inhibition. | 2006 | FASEB J. | pmid:16816110 |
| Rossoni G et al. | Nitric oxide and prostacyclin pathways: an integrated mechanism that limits myocardial infarction progression in anaesthetized rats. | 2006 | Pharmacol. Res. | pmid:16488624 |
| Lepäntalo A et al. | Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients. | 2006 | Thromb. Haemost. | pmid:16493486 |
| Kurosawa S et al. | Effects of ulinastatin on pulmonary artery pressure during abdominal aortic aneurysmectomy. | 2006 | J Clin Anesth | pmid:16517327 |
| Flipo RM | [Are the NSAIDs able to compromising the cardio-preventive efficacy of aspirin?]. | 2006 | Presse Med | pmid:17078596 |
| Dołegowska B et al. | Metabolism of eicosanoids and their action on renal function during ischaemia and reperfusion: the effect of alprostadil. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17011760 |
| Ong TZ et al. | Nonsteroidal anti-inflammatory drug use is a significant cause of peptic ulcer disease in a tertiary hospital in Singapore: a prospective study. | 2006 | J. Clin. Gastroenterol. | pmid:17016134 |
| Morchón R et al. | High levels of serum thromboxane B2 are generated during human pulmonary dirofilariosis. | 2006 | Clin. Vaccine Immunol. | pmid:17028222 |
| Cook-Johnson RJ et al. | Endothelial cell COX-2 expression and activity in hypoxia. | 2006 | Biochim. Biophys. Acta | pmid:17046322 |
| Faraday N et al. | Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population. | 2006 | Am. J. Cardiol. | pmid:16950183 |
| Renda G et al. | Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease. | 2006 | Clin. Pharmacol. Ther. | pmid:16952493 |
| Gabler NK et al. | Dietary onion intake as part of a typical high fat diet improves indices of cardiovascular health using the mixed sex pig model. | 2006 | Plant Foods Hum Nutr | pmid:17123162 |
| Venturinelli ML et al. | Platelet activation in different clinical forms of the coronary artery disease (role of P-selectin and others platelet markers in stable and unstable angina). | 2006 | Arq. Bras. Cardiol. | pmid:17128313 |
| Zhao Y et al. | Effect of a Chinese herbal formula, Shi-Bi-Lin, on an experimental model of allergic rhinitis. | 2006 | Ann. Allergy Asthma Immunol. | pmid:16802773 |
| Lee KS et al. | Antiplatelet activity of [5-(2-methoxy-5-chlorophenyl)furan-2-ylcarbonyl]guanidine (KR-32570), a novel sodium/hydrogen exchanger-1 and its mechanism of action. | 2006 | Arch. Pharm. Res. | pmid:16756082 |
| Peck OM et al. | The phosphatidylinositol 3 kinase pathway regulates tolerance to lipopolysaccharide and priming responses to Staphylococcus aureus and lipopolysaccharide. | 2006 | Shock | pmid:16783195 |
| Frelinger AL et al. | Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. | 2006 | Circulation | pmid:16785341 |
| Cox D et al. | Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers. | 2006 | Stroke | pmid:16794200 |
| Munsterhjelm E et al. | Influence on platelet aggregation of i.v. parecoxib and acetaminophen in healthy volunteers. | 2006 | Br J Anaesth | pmid:16698862 |
| Nakamura K et al. | Effects of atorvastatin and aspirin combined therapy on inflammatory responses in patients undergoing coronary artery bypass grafting. | 2006 | Cytokine | pmid:17300951 |
| Vranic II et al. | Adenosine cardioprotection study in clinical setting of paroxysmal supraventricular tachycardia. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16682179 |
| Huntjens DR et al. | Correlation between in vitro and in vivo concentration-effect relationships of naproxen in rats and healthy volunteers. | 2006 | Br. J. Pharmacol. | pmid:16682968 |
| Park HS et al. | Dietary trans-10, cis-12 and cis-9,trans-11 conjugated linoleic acids induce apoptosis in the colonic mucosa of rats treated with 1,2-dimethylhydrazine. | 2006 | J Med Food | pmid:16579724 |
| Ohmori T et al. | Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity: involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients. | 2006 | J. Thromb. Haemost. | pmid:16706971 |
| Perneby C et al. | Dose- and time-dependent antiplatelet effects of aspirin. | 2006 | Thromb. Haemost. | pmid:16601836 |
| Ahmadzadehfar H et al. | Passive cigarette smoking increases isoprostane formation. | 2006 | Life Sci. | pmid:16165164 |
| Niemi TT et al. | The effect of N-acetylcysteine on blood coagulation and platelet function in patients undergoing open repair of abdominal aortic aneurysm. | 2006 | Blood Coagul. Fibrinolysis | pmid:16607076 |
| Stergioulas AT and Filippou DK | Effects of physical conditioning on lipids and arachidonic acid metabolites in untrained boys: a longitudinal study. | 2006 | Appl Physiol Nutr Metab | pmid:16900233 |
| Fujimoto Y et al. | Monochloramine potently inhibits arachidonic acid metabolism in rat platelets. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16615995 |
| Xu S et al. | The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and proteinuria in diabetic apolipoprotein E-deficient mice. | 2006 | Diabetes | pmid:16380483 |
| Sánchez M et al. | Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats. | 2006 | J. Hypertens. | pmid:16331104 |
| Yang YY et al. | Roles of anandamide in the hepatic microcirculation in cirrhotic rats. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16407591 |
| Cyrus T et al. | Stabilization of advanced atherosclerosis in low-density lipoprotein receptor-deficient mice by aspirin. | 2006 | Atherosclerosis | pmid:16326168 |
| Chiang N et al. | Aspirin has a gender-dependent impact on antiinflammatory 15-epi-lipoxin A4 formation: a randomized human trial. | 2006 | Arterioscler. Thromb. Vasc. Biol. | pmid:16293793 |
| Wolfram RM et al. | Salivary isoprostanes indicate increased oxidation injury in periodontitis with additional tobacco abuse. | 2006 | Biofactors | pmid:17264390 |
| Murphy KJ et al. | Low dose supplementation with two different marine oils does not reduce pro-inflammatory eicosanoids and cytokines in vivo. | 2006 | Asia Pac J Clin Nutr | pmid:16837436 |
| González-Correa JA et al. | Influence of vitamin E on the antiplatelet effect of acetylsalicylic acid in human blood. | 2005 May-Jun | Platelets | pmid:16011961 |
| Zhao Y et al. | [The effect of desloratadine on the TXB2 and leukotrienes levels in the nasal lavage fluid of allergic rhinitis animal model]. | 2005 | Lin Chuang Er Bi Yan Hou Ke Za Zhi | pmid:16075993 |
| Song YM et al. | Effects of scorpion venom bioactive polypolypeptides on platelet aggregation and thrombosis and plasma 6-keto-PG F1alpha and TXB2 in rabbits and rats. | 2005 | Toxicon | pmid:15975616 |
| Hsiao G et al. | Protective mechanisms of inosine in platelet activation and cerebral ischemic damage. | 2005 | Arterioscler. Thromb. Vasc. Biol. | pmid:15976325 |
| Ueda T and Hashimoto T | [Thromboxane A2 (TXA2), thromboxane B2 (TXB2)]. | 2005 | Nippon Rinsho | pmid:16149442 |
| Léger CL et al. | A thromboxane effect of a hydroxytyrosol-rich olive oil wastewater extract in patients with uncomplicated type I diabetes. | 2005 | Eur J Clin Nutr | pmid:15798774 |
| Fimognari FL et al. | Nocturnal rise of urinary thromboxane B 2 in patients with coronary artery disease. | 2005 | Thromb. Haemost. | pmid:15735822 |
| Mayer AM et al. | Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines. | 2005 | BMC Pharmacol. | pmid:15762999 |
| Gerasimovska-Kitanovska B et al. | Decreased nitric oxide in women with essential hypertension in prehypertensive phase. | 2005 | Croat. Med. J. | pmid:16342341 |