Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chignard M et al. | Arachidonate-mediated bronchoconstriction and platelet activation are inhibited by microgram doses of compound L8027 which are not selective for thromboxane synthetase. | 1979 | Agents Actions Suppl. | pmid:291306 |
| Peskar BA and Holland A | Plasma levels of immunoreactive 15-keto-13,14-dihydro-thromboxane B2 in guinea pigs during anaphylaxis and after histamine injection. | 1979 | Agents Actions Suppl. | pmid:294148 |
| Cerletti C et al. | Comparison of the effects of oral and intravenous aspirin administration on platelet and peripheral vascular cyclo-oxygenase activity: studies in rats and in man. | 1986 | Agents Actions Suppl. | pmid:3101444 |
| Mihai K et al. | Association between total cholesterol and thromboxane B2 levels in offspring of parents suffering from premature coronary artery disease. | 1992 | Agents Actions Suppl. | pmid:1632293 |
| Petö J et al. | Association between total cholesterol and plasma thromboxane B2 in human adults. | 1992 | Agents Actions Suppl. | pmid:1632296 |
| Mentz P and Giessler C | Biosynthesis of TXB2 and 6-oxo-PGF1 alpha in the heart and other tissues under pathophysiological conditions. | 1992 | Agents Actions Suppl. | pmid:1632315 |
| Fernández-Cruz E et al. | Increased synthesis and production of prostaglandin E2 by monocytes from drug addicts with AIDS. | 1989 | AIDS | pmid:2496725 |
| Shalina RI et al. | [Synthesis of prostaglandins and lipid peroxidation in pregnant women with gestosis]. | 1988 | Akush Ginekol (Mosk) | pmid:3213902 |
| Bashakin NF et al. | [The functional characteristics of the prostacyclin-thromboxane system in newborn infants with a history of acute and chronic intrauterine hypoxia]. | 1993 | Akush Ginekol (Mosk) | pmid:8311150 |
| Siler-Khodr TM et al. | Effect of ethanol on thromboxane and prostacyclin production in the human placenta. | 2000 | Alcohol | pmid:10963940 |
| Hillbom M et al. | Effects of ethanol on platelet function. | 1985 May-Jun | Alcohol | pmid:4026960 |
| Signore C et al. | Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day. | 2008 | Alcohol. Clin. Exp. Res. | pmid:18715278 |
| Collins CE et al. | Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791957 |
| Treiber G et al. | The effect of single-dose naproxen on eicosanoid formation in human gastroduodenal mucosa. | 2006 | Aliment. Pharmacol. Ther. | pmid:16393293 |
| Van Hecken A et al. | Effects of enteric-coated, low-dose aspirin on parameters of platelet function. | 2002 | Aliment. Pharmacol. Ther. | pmid:12197849 |
| Cole AT et al. | Low dose aspirin: selective inhibition of rectal dialysis thromboxane B2 in healthy volunteers. | 1994 | Aliment. Pharmacol. Ther. | pmid:7865644 |
| Carty E et al. | Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848666 |
| Wannhoff A et al. | Cardiac volume overload and pulmonary hypertension in long-term follow-up of patients with a transjugular intrahepatic portosystemic shunt. | 2016 | Aliment. Pharmacol. Ther. | pmid:26919285 |
| Oosaki R et al. | Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. | 1997 | Allergy | pmid:9188934 |
| Mita H et al. | Possible involvement of mast-cell activation in aspirin provocation of aspirin-induced asthma. | 2001 | Allergy | pmid:11703219 |