Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yu C et al. | Effects of danshensu on platelet aggregation and thrombosis: in vivo arteriovenous shunt and venous thrombosis models in rats. | 2014 | PLoS ONE | pmid:25375124 |
Ross S et al. | Association of cyclooxygenase-2 genetic variant with cardiovascular disease. | 2014 | Eur. Heart J. | pmid:24796340 |
Shimizu T et al. | Up-regulation of Kv7.1 channels in thromboxane A2-induced colonic cancer cell proliferation. | 2014 | Pflugers Arch. | pmid:23995773 |
DeFilippis AP et al. | Fatty acids and TxA(2) generation, in the absence of platelet-COX-1 activity. | 2014 | Nutr Metab Cardiovasc Dis | pmid:24370448 |
Togna AR et al. | 4-Methylcoumarin derivatives with anti-inflammatory effects in activated microglial cells. | 2014 | Biol. Pharm. Bull. | pmid:24389482 |
Osmond DA et al. | Clopidogrel preserves whole kidney autoregulatory behavior in ANG II-induced hypertension. | 2014 | Am. J. Physiol. Renal Physiol. | pmid:24477682 |
Cathcart MC et al. | Thromboxane synthase expression and correlation with VEGF and angiogenesis in non-small cell lung cancer. | 2014 | Biochim. Biophys. Acta | pmid:24480048 |
Umar A et al. | Effect of Ocimum basilicum L. on cyclo-oxygenase isoforms and prostaglandins involved in thrombosis. | 2014 | J Ethnopharmacol | pmid:24412551 |
Sahota T et al. | Model-based analysis of thromboxane Bâ‚‚ and prostaglandin Eâ‚‚ as biomarkers in the safety evaluation of naproxen. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24667227 |
Gonçalves LH et al. | Acetylsalicylic acid therapy: influence of metformin use and other variables on urinary 11-dehydrothromboxane B2 levels. | 2014 | Clin. Chim. Acta | pmid:24316050 |
Jiménez-Romero C et al. | Dactyloditerpenol acetate, a new prenylbisabolane-type diterpene from Aplysia dactylomela with significant in vitro anti-neuroinflammatory activity. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24279991 |
Chou YI et al. | Correlations of platelet-derived microparticles with thromboxane B2, platelet-activating factor, endothelin-1, and neutrophil to lymphocyte ratio in patients with coronary intermediate lesions. | 2014 | Biomarkers | pmid:25391885 |
Montserrat-de la Paz S et al. | Long-chain fatty alcohols from evening primrose oil inhibit the inflammatory response in murine peritoneal macrophages. | 2014 | J Ethnopharmacol | pmid:24239848 |
Wang Y et al. | DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4. | 2014 | BMC Complement Altern Med | pmid:24555740 |
Fuentes E et al. | A novel role of Eruca sativa Mill. (rocket) extract: antiplatelet (NF-κB inhibition) and antithrombotic activities. | 2014 | Nutrients | pmid:25514563 |
Santos-Gallego CG and Badimon JJ | The sum of two evils: pneumonia and myocardial infarction: is platelet activation the missing link? | 2014 | J. Am. Coll. Cardiol. | pmid:25444148 |
Cangemi R et al. | Platelet activation is associated with myocardial infarction in patients with pneumonia. | 2014 | J. Am. Coll. Cardiol. | pmid:25444147 |
Mayer AM et al. | Vibrio vulnificus MO6-24/O lipopolysaccharide stimulates superoxide anion, thromboxane Bâ‚‚, matrix metalloproteinase-9, cytokine and chemokine release by rat brain microglia in vitro. | 2014 | Mar Drugs | pmid:24675728 |
van den Elsen LW et al. | Dietary fish oil improves endothelial function and lowers blood pressure via suppression of sphingolipid-mediated contractions in spontaneously hypertensive rats. | 2014 | J. Hypertens. | pmid:24569415 |
Reddoch KM et al. | Hemostatic function of apheresis platelets stored at 4°C and 22°C. | 2014 | Shock | pmid:24169210 |