Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pain D010146 64 associated lipids
Contusions D003288 3 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Pleurisy D010998 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Gastritis D005756 27 associated lipids
Heart Failure D006333 36 associated lipids
Pulmonary Edema D011654 23 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypothyroidism D007037 32 associated lipids
Rhinitis D012220 10 associated lipids
Hypercapnia D006935 5 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Pain, Postoperative D010149 13 associated lipids
Asthma D001249 52 associated lipids
Kidney Diseases D007674 29 associated lipids
Femoral Fractures D005264 7 associated lipids
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Ulcer D014456 16 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Endometriosis D004715 29 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Myocardial Infarction D009203 21 associated lipids
Proteinuria D011507 30 associated lipids
Arteriosclerosis D001161 86 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Fibrosis D005355 23 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Fetal Diseases D005315 8 associated lipids
Glomerulonephritis D005921 35 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Sepsis D018805 11 associated lipids
Leukopenia D007970 9 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Stroke D020521 32 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Brain Ischemia D002545 89 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Seizures D012640 87 associated lipids
Peptic Ulcer D010437 19 associated lipids
Birth Weight D001724 23 associated lipids
Hypertension D006973 115 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Thromboembolism D013923 6 associated lipids
Nasal Polyps D009298 26 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Eizayaga FX et al. Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension. 2007 World J. Gastroenterol. pmid:17876871
Ciabattoni G et al. Determinants of platelet activation in Alzheimer's disease. 2007 Neurobiol. Aging pmid:16442186
De Candia E et al. Defective platelet responsiveness to thrombin and protease-activated receptors agonists in a novel case of gray platelet syndrome: correlation between the platelet defect and the alpha-granule content in the patient and four relatives. 2007 J. Thromb. Haemost. pmid:17137471
Miyamoto A et al. Ibuprofen or ozagrel increases NO release and l-nitro arginine induces TXA(2) release from cultured porcine basilar arterial endothelial cells. 2007 Vascul. Pharmacol. pmid:17113355
Ansari HR et al. Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17921329
Ivandic BT et al. Determination of aspirin responsiveness by use of whole blood platelet aggregometry. 2007 Clin. Chem. pmid:17332149
Calzada C et al. In vitro glycoxidized low-density lipoproteins and low-density lipoproteins isolated from type 2 diabetic patients activate platelets via p38 mitogen-activated protein kinase. 2007 J. Clin. Endocrinol. Metab. pmid:17341567
Eligini S et al. Paracrine up-regulation of monocyte cyclooxygenase-2 by platelets: role of transforming growth factor-beta1. 2007 Cardiovasc. Res. pmid:17250815
Sood BG et al. PGE2/TXB2 imbalance in neonatal hypoxemic respiratory failure. 2007 Acta Paediatr. pmid:17376184
Coppinger JA et al. Moderation of the platelet releasate response by aspirin. 2007 Blood pmid:17303692
Graff J et al. Effects of parecoxib and dipyrone on platelet aggregation in patients undergoing meniscectomy: a double-blind, randomized, parallel-group study. 2007 Clin Ther pmid:17577465
Crescente M et al. Gallic acid, a dietary polyphenolic component, blunts the inhibition of platelet COX-1 by aspirin: preliminary in-vitro findings. 2007 Thromb. Haemost. pmid:17549313
Undas A et al. Lack of aspirin-induced decrease in thrombin formation in subjects resistant to aspirin. 2007 Thromb. Haemost. pmid:17549314
Chakroun T et al. Screening for aspirin resistance in stable coronary artery patients by three different tests. 2007 Thromb. Res. pmid:17553552
Pucsok JM et al. Effect of exercise on levels of cyclo-oxygenase mediators in exhaled breath condensate in elite athletes. 2007 J Sports Med Phys Fitness pmid:17557063
Hohlfeld T et al. Variable platelet response to aspirin in patients with ischemic stroke. 2007 Cerebrovasc. Dis. pmid:17519543
Allais G et al. Naproxen sodium in short-term prophylaxis of pure menstrual migraine: pathophysiological and clinical considerations. 2007 Neurol. Sci. pmid:17508177
Wong PC et al. Platelet aggregometry and receptor binding to predict the magnitude of antithrombotic and bleeding time effects of clopidogrel in rabbits. 2007 J. Cardiovasc. Pharmacol. pmid:17513951
Hsiao G et al. Characterization of a novel and potent collagen antagonist, caffeic acid phenethyl ester, in human platelets: in vitro and in vivo studies. 2007 Cardiovasc. Res. pmid:17560560
Basselin M et al. Flurbiprofen, a cyclooxygenase inhibitor, reduces the brain arachidonic acid signal in response to the cholinergic muscarinic agonist, arecoline, in awake rats. 2007 Neurochem. Res. pmid:17562170
Aras-Lopéz R et al. Dexamethasone decreases contraction to electrical field stimulation in mesenteric arteries from spontaneously hypertensive rats through decreases in thromboxane A2 release. 2007 J. Pharmacol. Exp. Ther. pmid:17562850
Gurbel PA et al. Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study. 2007 Circulation pmid:17562955
Tu CT et al. Antifibrotic activity of rofecoxib in vivo is associated with reduced portal hypertension in rats with carbon tetrachloride-induced liver injury. 2007 J. Gastroenterol. Hepatol. pmid:17565644
Zheng BH et al. [The effect of inhaled nitric oxide on endothelium-derived angiokinetic factors in patients with acute high altitude disease]. 2007 Zhonghua Jie He He Hu Xi Za Zhi pmid:17445476
Luceri C et al. p-Coumaric acid, a common dietary phenol, inhibits platelet activity in vitro and in vivo. 2007 Br. J. Nutr. pmid:17313706
Basselin M et al. Chronic carbamazepine administration reduces N-methyl-D-aspartate receptor-initiated signaling via arachidonic acid in rat brain. 2007 Biol. Psychiatry pmid:17628508
Bray PF et al. Heritability of platelet function in families with premature coronary artery disease. 2007 J. Thromb. Haemost. pmid:17663734
Chang MC et al. Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization. 2007 Br. J. Pharmacol. pmid:17641677
Li XM et al. [Physiological effects of cold and cool Chinese herbal medicine of channel tropism of stomach on rats with stomach-heat syndrome]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17672345
Park JB Caffedymine from cocoa has COX inhibitory activity suppressing the expression of a platelet activation marker, P-selectin. 2007 J. Agric. Food Chem. pmid:17319684
Guthikonda S et al. Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin. 2007 J. Thromb. Haemost. pmid:17319904
Rohatagi S et al. Predictive population pharmacokinetic/pharmacodynamic model for a novel COX-2 inhibitor. 2007 J Clin Pharmacol pmid:17322148
González-Correa JA et al. Differences in the influence of the interaction between acetylsalicylic acid and salicylic acid on platelet function in whole blood and isolated platelets: influence of neutrophils. 2007 Pharmacol. Res. pmid:17644353
Gendron ME and Thorin E A change in the redox environment and thromboxane A2 production precede endothelial dysfunction in mice. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17644574
Weber AA et al. Effects of selective cyclooxygenase isoform inhibition on systemic prostacyclin synthesis and on platelet function at rest and after exercise in healthy volunteers. 2007 Platelets pmid:17654308
Sun LQ et al. [Relationship between syndrome differentiation of traditional Chinese medicine and vascular endothelial function in patients with diabetic arterial occlusion of lower extremities]. 2007 Zhong Xi Yi Jie He Xue Bao pmid:17997934
Marvin CC et al. Synthesis of thromboxane B2 via ketalization/ring-closing metathesis. 2007 Org. Lett. pmid:18047355
Wang Z et al. Changes of vasoactive polypeptides during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage. 2007 Chin. Med. J. pmid:18167188
DiChiara J et al. The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study. 2007 Diabetes pmid:17848625
Sha JP et al. [Effect of the recombinant staphylokinase on pancreatic ischemia in severe acute pancreatitis of rats]. 2007 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:17708840
Capone ML et al. Human pharmacology of naproxen sodium. 2007 J. Pharmacol. Exp. Ther. pmid:17473175
Maksimova MIu et al. [Hemorheology and homeostasis in the most acute stage of lacunar stroke]. 2007 Zh Nevrol Psikhiatr Im S S Korsakova pmid:18427452
Yousefipour Z et al. Ciglitazone, a peroxisome proliferator-activated receptor gamma inducer, ameliorates renal preglomerular production and activity of angiotensin II and thromboxane A2 in glycerol-induced acute renal failure. 2007 J. Pharmacol. Exp. Ther. pmid:17494862
Holma R et al. Prophylactic potential of montelukast against mild colitis induced by dextran sulphate sodium in rats. 2007 J. Physiol. Pharmacol. pmid:17928642
Bogani P et al. Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil. 2007 Atherosclerosis pmid:16488419
Vidal C et al. Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis. 2007 J. Pharmacol. Exp. Ther. pmid:17015640
Sekine S et al. Lowering systolic blood pressure and increases in vasodilator levels in SHR with oral alpha-linolenic acid administration. 2007 J Oleo Sci pmid:17898500
Dawood MY and Khan-Dawood FS Differential suppression of menstrual fluid prostaglandin F2a, prostaglandin E2, 6-keto prostaglandin F1a and thromboxane B2 by suprofen in women with primary dysmenorrhea. 2007 Prostaglandins Other Lipid Mediat. pmid:17259081
Jin UH et al. Inhibitory effect of Panax notoginseng on nitric oxide synthase, cyclo-oxygenase-2 and neutrophil functions. 2007 Phytother Res pmid:17128437
Yang YY et al. Effect of chronic CB1 cannabinoid receptor antagonism on livers of rats with biliary cirrhosis. 2007 Clin. Sci. pmid:17176248