Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nakano T et al. | Effects of platelet depletion on PMA-induced acute lung injury in awake sheep. | 1995 | Respir Physiol | pmid:8570923 |
Sorem KA and Siler-Khodr TM | Placental prostanoid release in severe intrauterine growth retardation. | 1995 | Placenta | pmid:8570572 |
Kobayashi I et al. | Saiboku-To, a herbal extract mixture, selectively inhibits 5-lipoxygenase activity in leukotriene synthesis in rat basophilic leukemia-1 cells. | 1995 | J Ethnopharmacol | pmid:8569245 |
Altavilla D et al. | G 619, a dual thromboxane synthase inhibitor and thromboxane A2 receptor antagonist, inhibits tumor necrosis factor-alpha biosynthesis. | 1995 | Eur. J. Pharmacol. | pmid:8566149 |
Glaser K et al. | Etodolac selectively inhibits human prostaglandin G/H synthase 2 (PGHS-2) versus human PGHS-1. | 1995 | Eur. J. Pharmacol. | pmid:8566109 |
Kawikova I et al. | Bradykinin-induced release of thromboxane B2 into bronchoalveolar lavage fluid of guinea pigs: relationship to airflow obstruction. | 1995 | Eur. J. Pharmacol. | pmid:8566097 |
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Kato A et al. | Role of thromboxane A2 and prostacyclin in uninephrectomy-induced attenuation of ischemic renal injury. | 1995 | Kidney Int. | pmid:8544417 |
Daugschies A | Oesophagostomum dentatum: population dynamics and synthesis of prostanoids by histotropic stages cultured in vitro. | 1995 | Exp. Parasitol. | pmid:8542999 |
Lees P et al. | Pharmacodynamics and pharmacokinetics of carprofen in the horse. | 1994 | Equine Vet. J. | pmid:8542839 |
Blache D et al. | Occurrence and biological effects of cholesteryl sulfate on blood platelets. | 1995 | Biochim. Biophys. Acta | pmid:8541337 |
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Smith AJ et al. | Hypertensive and normal pregnancy: a longitudinal study of blood pressure, distensibility of dorsal hand veins and the ratio of the stable metabolites of thromboxane A2 and prostacyclin in plasma. | 1995 | Br J Obstet Gynaecol | pmid:8534627 |
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Rabinovici R et al. | ARDS-like lung injury produced by endotoxin in platelet-activating factor-primed rats. | 1993 | J. Appl. Physiol. | pmid:8514698 |
Renz H et al. | Tumor necrosis factor-alpha, interleukin 1, eicosanoid, and hydrogen peroxide release from macrophages exposed to glove starch particles. | 1993 | Clin. Immunol. Immunopathol. | pmid:8513589 |
Dunn CW and Horton JW | Role of angiotensin II in neonatal sepsis. | 1993 | Circ. Shock | pmid:8508519 |
Fletcher JR et al. | Tumor necrosis factor-induced mortality is reversed with cyclooxygenase inhibition. | 1993 | Ann. Surg. | pmid:8507112 |
Fisher M | Increased thromboxane biosynthesis in patients with acute cerebral ischemia. | 1993 | Stroke | pmid:8506568 |
Budd JS et al. | The effectiveness of low dose slow release aspirin as an antiplatelet agent. | 1993 | J R Soc Med | pmid:8505747 |
Penning LC et al. | Ca(2+)-mediated prostaglandin E2 induction reduces haematoporphyrin-derivative-induced cytotoxicity of T24 human bladder transitional carcinoma cells in vitro. | 1993 | Biochem. J. | pmid:8503851 |
Ferretti A et al. | Ingestion of marine oil reduces excretion of 11-dehydrothromboxane B2, an index of intravascular production of thromboxane A2. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8497491 |
Ciabattoni G et al. | Effects of vasoactive intestinal polypeptide on antigen-induced bronchoconstriction and thromboxane release in guinea-pig lung. | 1993 | Br. J. Pharmacol. | pmid:8495242 |
Schneidkraut MJ and Carlson RW | Cecal ligation and puncture is associated with pulmonary injury in the rat: role of cyclooxygenase pathway products. | 1993 | Prostaglandins | pmid:8493358 |
Mustad VA et al. | Comparison of the effects of diets rich in stearic acid versus myristic acid and lauric acid on platelet fatty acids and excretion of thromboxane A2 and PGI2 metabolites in healthy young men. | 1993 | Metab. Clin. Exp. | pmid:8487669 |
Zwischenberger JB et al. | Pathophysiology of ovine smoke inhalation injury treated with extracorporeal membrane oxygenation. | 1993 | Chest | pmid:8486048 |
Yamanaka S et al. | 11-Dehydro thromboxane B2: a reliable parameter of thromboxane A2 production in dogs. | 1993 | Prostaglandins | pmid:8484010 |
Alanko J | Effects of phenols on eicosanoid synthesis in A23187-stimulated human whole blood. | 1993 | Prostaglandins | pmid:8484008 |
Yasu T et al. | Effects of aspirin DL-lysine on thrombin generation in unstable angina pectoris. | 1993 | Am. J. Cardiol. | pmid:8480641 |
Böck M et al. | Storage of single-donor platelet concentrates: metabolic and functional changes. | 1993 | Transfusion | pmid:8480351 |
Smith CC et al. | The influence of aspirin on plasma and platelet catecholamine levels, and platelet function in normal man. | 1993 | Clin. Auton. Res. | pmid:8477181 |
Mohri H and Ohkubo T | Single-dose effect of enteric-coated aspirin on platelet function and thromboxane generation in middle-aged men. | 1993 | Ann Pharmacother | pmid:8477113 |
Hauth JC et al. | Low-dose aspirin therapy to prevent preeclampsia. | 1993 | Am. J. Obstet. Gynecol. | pmid:8475955 |
Arruzazabala ML et al. | Effects of Policosanol on platelet aggregation in rats. | 1993 | Thromb. Res. | pmid:8475481 |
Ciabattoni G et al. | Aspirin, but not heparin, suppresses the transient increase in thromboxane biosynthesis associated with cardiac catheterization or coronary angioplasty. | 1993 | J. Am. Coll. Cardiol. | pmid:8473644 |
Kroegel C and Matthys H | Platelet-activating factor-induced human eosinophil activation. Generation and release of cyclo-oxygenase metabolites in human blood eosinophils from asthmatics. | 1993 | Immunology | pmid:8473016 |
Sagripanti A et al. | [The use of picotamide in nephropathy with mesangial IgA deposits. The effect on thromboxane generation]. | 1993 | Clin Ter | pmid:8472511 |
Elmadfa I et al. | Influence of a single parenteral application of a 10% fish oil emulsion on plasma fatty acid pattern and the function of thrombocytes in young adult men. | 1993 | Ann. Nutr. Metab. | pmid:8470873 |
GarcÃa-Valdecasas JC et al. | Prostaglandin metabolism and hemodynamic alterations during human liver transplantation. | 1993 | Transplant. Proc. | pmid:8470202 |
Lueddeckens G et al. | Importance of secondary TXA2 release in mediating of endothelin-1 induced bronchoconstriction and vasopressin in the guinea-pig. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8469685 |
Byrne JG et al. | Cardiac-derived thromboxane A2. An initiating mediator of reperfusion injury? | 1993 | J. Thorac. Cardiovasc. Surg. | pmid:8469003 |
Grieve EM et al. | The reversal of experimental cyclosporin A nephrotoxicity by thromboxane synthetase inhibition. | 1993 | Biochem. Pharmacol. | pmid:8466554 |