Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Schiff E et al. | Reduction of thromboxane A2 synthesis in pregnancy by polyunsaturated fatty acid supplements. | 1993 | Am. J. Obstet. Gynecol. | pmid:8420313 |
| Van Assche FA et al. | Increased thromboxane formation in diabetic pregnancy as a possible contributor to preeclampsia. | 1993 | Am. J. Obstet. Gynecol. | pmid:8420355 |
| Mäkäräinen L and Ylikorkala O | Amniotic fluid 6-keto-prostaglandin F1 alpha and thromboxane B2 during labor. | 1984 | Am. J. Obstet. Gynecol. | pmid:6388335 |
| Fantone JC et al. | Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. | 1984 | Am. J. Pathol. | pmid:6324595 |
| Cybulsky AV et al. | A role for thromboxane in complement-mediated glomerular injury. | 1987 | Am. J. Pathol. | pmid:3111267 |
| Zoja C et al. | Selective inhibition of platelet thromboxane generation with low-dose aspirin does not protect rats with reduced renal mass from the development of progressive disease. | 1989 | Am. J. Pathol. | pmid:2497648 |
| Lundberg C et al. | C5a-induced hemodynamic and hematologic changes in the rabbit. Role of cyclooxygenase products and polymorphonuclear leukocytes. | 1987 | Am. J. Pathol. | pmid:3115110 |
| Stimler NP and O'Flaherty JT | Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues. | 1983 | Am. J. Pathol. | pmid:6624879 |
| Woods LW et al. | Structural and biochemical changes in lungs of 3-methylindole-treated rats. | 1993 | Am. J. Pathol. | pmid:8424451 |
| Diamond JR et al. | Altered functional characteristics of rat macrophages during nephrosis. Synergistic effects of hypercholesterolemia. | 1989 | Am. J. Pathol. | pmid:2801885 |
| Cook HT et al. | Functional characteristics of macrophages in glomerulonephritis in the rat. O2- generation, MHC class II expression, and eicosanoid synthesis. | 1989 | Am. J. Pathol. | pmid:2537019 |
| Mundie TG et al. | Byssinosis: Release of prostaglandins, thromboxane, and 5-hydroxytryptamine in bronchopulmonary lavage fluid after inhalation of cotton dust extracts. | 1985 | Am. J. Pathol. | pmid:3966532 |
| Bertani T et al. | Tumor necrosis factor induces glomerular damage in the rabbit. | 1989 | Am. J. Pathol. | pmid:2916653 |
| Hamilton J et al. | Platelet interaction with a pancreatic ascites tumor. | 1986 | Am. J. Pathol. | pmid:3510553 |
| Nanji AA et al. | Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2. | 1993 | Am. J. Pathol. | pmid:8382006 |
| Nath KA et al. | Regulatory role of prostanoids in glomerular microcirculation of remnant nephrons. | 1987 | Am. J. Physiol. | pmid:3578532 |
| Schuette AH et al. | Effect of lung thromboxane generation on regional blood flow during sheep bypass. | 1982 | Am. J. Physiol. | pmid:7065206 |
| Yamamoto S et al. | Endothelin causes portal and pulmonary hypertension in porcine endotoxemic shock. | 1997 | Am. J. Physiol. | pmid:9087598 |
| Düsing R et al. | Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. | 1983 | Am. J. Physiol. | pmid:6337507 |
| Wilkes BM and Mento PF | Bradykinin-induced vasoconstriction and thromboxane release in perfused human placenta. | 1988 | Am. J. Physiol. | pmid:3377072 |
| Abernathy VJ et al. | C-reactive protein inhibits increased pulmonary vascular permeability induced by fMLP in isolated rabbit lungs. | 1996 | Am. J. Physiol. | pmid:8770090 |
| Olson KR et al. | Cardiovascular effects of homologous bradykinin in rainbow trout. | 1997 | Am. J. Physiol. | pmid:9140009 |
| Closa D et al. | Hepatic involvement in pancreatitis-induced lung damage. | 1996 | Am. J. Physiol. | pmid:8772495 |
| Strand JC et al. | Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. | 1981 | Am. J. Physiol. | pmid:6787931 |
| Peterson MB et al. | Thromboxane mediates acute pulmonary hypertension in sheep extracorporeal perfusion. | 1982 | Am. J. Physiol. | pmid:7051860 |
| Nishijima MK et al. | Effect of naloxone and ibuprofen on organ blood flow during endotoxic shock in pig. | 1988 | Am. J. Physiol. | pmid:3394818 |
| Katusić ZS et al. | Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery. | 1993 | Am. J. Physiol. | pmid:8456988 |
| Simonson MS et al. | Identification and transmembrane signaling of leukotriene D4 receptors in human mesangial cells. | 1988 | Am. J. Physiol. | pmid:2849305 |
| Olson NC et al. | Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs. | 1993 | Am. J. Physiol. | pmid:8460710 |
| Chang SW and Ohara N | Increased pulmonary vascular permeability in rats with biliary cirrhosis: role of thromboxane A2. | 1993 | Am. J. Physiol. | pmid:8460713 |
| Toyofuku T et al. | Pulmonary vascular response to platelet-activating factor in conscious sheep. | 1988 | Am. J. Physiol. | pmid:3414811 |
| Widdicombe JH et al. | Release of cyclooxygenase products from primary cultures of tracheal epithelia of dog and human. | 1989 | Am. J. Physiol. | pmid:2514604 |
| Zipser RD and Martin K | Urinary excretion of arterial blood prostaglandins and thromboxanes in man. | 1982 | Am. J. Physiol. | pmid:6950668 |
| Vanderhoof JA et al. | Reduced mucosal prostaglandin synthesis after massive small bowel resection. | 1988 | Am. J. Physiol. | pmid:3279815 |
| Amsterdam EA et al. | Contractile actions of C5a on isolated porcine myocardium. | 1992 | Am. J. Physiol. | pmid:1357981 |
| Utsunomiya T et al. | Modification of inflammatory response to aspiration with ibuprofen. | 1982 | Am. J. Physiol. | pmid:6756172 |
| Del Maschio A et al. | Platelet activation by polymorphonuclear leukocytes exposed to chemotactic agents. | 1990 | Am. J. Physiol. | pmid:2156456 |
| Stephenson AH et al. | 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. | 1998 | Am. J. Physiol. | pmid:9688901 |
| Kruse-Elliott KT and Olson NC | CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. | 1993 | Am. J. Physiol. | pmid:8386479 |
| Greenberg S et al. | Pulmonary vascular smooth muscle function in porcine splanchnic arterial occlusion shock. | 1981 | Am. J. Physiol. | pmid:7246787 |
| Schlondorff D and Satriano JA | Interactions of vasopressin, cAMP, and prostaglandins in toad urinary bladder. | 1985 | Am. J. Physiol. | pmid:2579584 |
| Stahl RA et al. | Glomerular prostaglandin formation in two-kidney, one-clip hypertensive rats. | 1984 | Am. J. Physiol. | pmid:6507633 |
| Stenmark KR et al. | Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension. | 1985 | Am. J. Physiol. | pmid:3923843 |
| Scharschmidt LA et al. | Angiotensin II and eicosanoids in the control of glomerular size in the rat and human. | 1986 | Am. J. Physiol. | pmid:2936254 |
| Adler S et al. | Biphasic effect of oxygen radicals on prostaglandin production by rat mesangial cells. | 1987 | Am. J. Physiol. | pmid:3105332 |
| Cudd TA and Wood CE | Thromboxane A2 receptor antagonism prevents hormonal and cardiovascular responses to mineral acid infusion. | 1994 | Am. J. Physiol. | pmid:7977850 |
| Wagerle LC et al. | Effect of dexamethasone on cerebral prostanoid formation and pial arteriolar reactivity to CO2 in newborn pigs. | 1991 | Am. J. Physiol. | pmid:1901460 |
| Benigni A et al. | Renal metabolism and urinary excretion of thromboxane B2 in the rat. | 1989 | Am. J. Physiol. | pmid:2750927 |
| Del Balzo U et al. | Complement C5a-mediated myocardial ischemia and neutrophil sequestration: two independent phenomena. | 1993 | Am. J. Physiol. | pmid:8447449 |
| Titos E et al. | Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4). | 1999 | Am. J. Physiol. | pmid:10564079 |
| Takashio T et al. | Inhibitory effect of pindolol on hypoxic pulmonary vasoconstriction. | 1992 | Am. J. Physiol. | pmid:1310232 |
| Schrör K et al. | Preservation of ischemic myocardium by pinane thromboxane A2. | 1980 | Am. J. Physiol. | pmid:7356037 |
| Sata T et al. | Paraquat-induced lung injury: prevention by N-tert-butyl-alpha-phenylnitrone, a free-radical spin-trapping agent. | 1992 | Am. J. Physiol. | pmid:1311515 |
| Chakraborti S et al. | Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium. | 1989 | Am. J. Physiol. | pmid:2514605 |
| Hollenberg SM et al. | Eicosanoid production by human aortic endothelial cells in response to endothelin. | 1994 | Am. J. Physiol. | pmid:7810729 |
| McGowan HM et al. | Dexamethasone attenuates reversal of hypertension in one-kidney, one-clip rats. | 1988 | Am. J. Physiol. | pmid:3177664 |
| Garfield RE et al. | Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. | 1980 | Am. J. Physiol. | pmid:7369350 |
| Lampugnani MG and de Gaetano G | Effects of metabolized and unmetabolized arachidonate on rat platelet shape change. | 1984 | Am. J. Physiol. | pmid:6433724 |
| Ahlquist DA et al. | Factors influencing metabolism of arachidonic acid in guinea pig gastric mucosa. | 1983 | Am. J. Physiol. | pmid:6401937 |
| Whinnery MA et al. | Thromboxane B2 and prostaglandin E2 in the rat kidney with unilateral ureteral obstruction. | 1982 | Am. J. Physiol. | pmid:6950670 |
| Murray MJ et al. | Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs. | 1995 | Am. J. Physiol. | pmid:8594921 |
| Wilkes BM et al. | Characterization of glomerular thromboxane receptor sites in the rat. | 1989 | Am. J. Physiol. | pmid:2525345 |
| Townsley MI et al. | Pulmonary embolism: analysis of endothelial pore sizes in canine lung. | 1988 | Am. J. Physiol. | pmid:3189571 |
| Nukina S et al. | Glycogenolytic effect of adenosine involves ATP from hepatocytes and eicosanoids from Kupffer cells. | 1994 | Am. J. Physiol. | pmid:8304463 |
| Grimminger F et al. | Differential influence of arachidonic vs. eicosapentaenoic acid on experimental pulmonary hypertension. | 1995 | Am. J. Physiol. | pmid:7611475 |
| Kalichman MW et al. | Effects of cocaine on blood flow and prostaglandin metabolites in rat sciatic nerve. | 1994 | Am. J. Physiol. | pmid:8024013 |
| Morel DR et al. | Leukotrienes, thromboxane A2, and prostaglandins during systemic anaphylaxis in sheep. | 1991 | Am. J. Physiol. | pmid:1716064 |
| Reyes AA and Klahr S | Bladder contributes to eicosanoids excreted in urine. | 1990 | Am. J. Physiol. | pmid:2240235 |
| Teitelbaum I et al. | Effect of cAMP on prostaglandin E2 production in cultured rat inner medullary collecting tubule cells. | 1986 | Am. J. Physiol. | pmid:3020997 |
| Klotman PE et al. | Thromboxane synthetase inhibition improves function of hydronephrotic rat kidneys. | 1986 | Am. J. Physiol. | pmid:3456211 |
| Himmelstein SI and Klotman PE | The role of thromboxane in two-kidney, one-clip Goldblatt hypertension in rats. | 1989 | Am. J. Physiol. | pmid:2527469 |
| Geisel J et al. | Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2. | 1994 | Am. J. Physiol. | pmid:7943269 |
| Chen L et al. | Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. | 1997 | Am. J. Physiol. | pmid:9362253 |
| Wilkes BM et al. | Endothelin receptors in human placenta: relationship to vascular resistance and thromboxane release. | 1990 | Am. J. Physiol. | pmid:2159236 |
| Beck N and Shaw JO | Thromboxane B2 and prostaglandin E2 in the K+-depleted rat kidney. | 1981 | Am. J. Physiol. | pmid:7468800 |
| Don BR et al. | Dietary protein intake modulates glomerular eicosanoid production in the rat. | 1989 | Am. J. Physiol. | pmid:2539749 |
| Reinke M | Monitoring thromboxane in body fluids: a specific ELISA for 11-dehydrothromboxane B2 using a monoclonal antibody. | 1992 | Am. J. Physiol. | pmid:1590375 |
| Podjarny E et al. | Prostanoids in renal failure induced by converting enzyme inhibition in sodium-depleted rats. | 1988 | Am. J. Physiol. | pmid:3162354 |
| Addonizio VP et al. | Effects of verapamil and diltiazem on human platelet function. | 1986 | Am. J. Physiol. | pmid:3006516 |
| Havill AM et al. | alpha-Naphthylthiourea produces dose-dependent lung vascular injury in sheep. | 1982 | Am. J. Physiol. | pmid:6812437 |
| Gyenes M and De Groot H | Prostanoid release by Kupffer cells upon hypoxia-reoxygenation: role of pHi and Cai2+. | 1993 | Am. J. Physiol. | pmid:8384798 |
| Brown GP and Venuto RC | In vitro renal eicosanoid production during pregnancy in rabbits. | 1988 | Am. J. Physiol. | pmid:3287949 |
| Perico N et al. | Functional significance of exaggerated renal thromboxane A2 synthesis induced by cyclosporin A. | 1986 | Am. J. Physiol. | pmid:3094383 |
| Burch RM and Halushka PV | Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells. | 1982 | Am. J. Physiol. | pmid:6816073 |
| Bradley LM et al. | Circulatory effects of PAF-acether in newborn piglets. | 1989 | Am. J. Physiol. | pmid:2912183 |
| Coceani F et al. | Prostaglandin E2 and thromboxane B2 in cerebrospinal fluid of afebrile and febrile cat. | 1983 | Am. J. Physiol. | pmid:6574712 |
| Zipser RD | Effects of selective inhibition of thromboxane synthesis on renal function in humans. | 1985 | Am. J. Physiol. | pmid:3839111 |
| Fletcher MP et al. | C5a-induced myocardial ischemia: role for CD18-dependent PMN localization and PMN-platelet interactions. | 1993 | Am. J. Physiol. | pmid:7902015 |
| Longhurst JC et al. | Increased concentration of leukotriene B4 but not thromboxane B2 in intestinal lymph of cats during brief ischemia. | 1992 | Am. J. Physiol. | pmid:1317130 |
| Toda N et al. | Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries. | 1992 | Am. J. Physiol. | pmid:1558175 |
| Kauser K and Rubanyi GM | Gender difference in bioassayable endothelium-derived nitric oxide from isolated rat aortae. | 1994 | Am. J. Physiol. | pmid:7810731 |
| Stahl RA et al. | High protein intake stimulates glomerular prostaglandin formation in remnant kidneys. | 1987 | Am. J. Physiol. | pmid:3473940 |
| Lorenz RR and Vanhoutte PM | Prejunctional adrenergic inhibition by aggregating platelets in canine blood vessels. | 1985 | Am. J. Physiol. | pmid:4037113 |
| Sirko S et al. | Prostaglandin formation in the hypothalamus in vivo: effect of pyrogens. | 1989 | Am. J. Physiol. | pmid:2784289 |
| Farman N et al. | PGE2, PGF2 alpha, 6-keto-PGF1 alpha, and TxB2 synthesis along the rabbit nephron. | 1987 | Am. J. Physiol. | pmid:3101513 |
| Brown GP and Venuto RC | Eicosanoid production in rabbit vascular tissues and placentas. | 1990 | Am. J. Physiol. | pmid:2316640 |
| Raj JU and Chen P | Role of eicosanoids in hypoxic vasoconstriction in isolated lamb lungs. | 1987 | Am. J. Physiol. | pmid:2820247 |
| Ito BR and Del Balzo U | Effect of platelet depletion and inhibition of platelet cyclooxygenase on C5a-mediated myocardial ischemia. | 1994 | Am. J. Physiol. | pmid:7943373 |
| Miyazaki Y et al. | Selective turnover of sarcolemmal phospholipids with lethal cardiac myocyte injury. | 1990 | Am. J. Physiol. | pmid:2382705 |
| Dunham BM et al. | Role of prostaglandins in positive end-expiratory pressure-induced negative inotropism. | 1981 | Am. J. Physiol. | pmid:7034549 |