Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mitchell MD et al. | Thromboxane B-2 in the plasma and amniotic fluid of late pregnant and periparturient sheep. | 1979 | J. Reprod. Fertil. | pmid:423152 |
| Tobelem G et al. | Further studies on a specific platelet antibody found in Bernard-Soulier syndrome and its effects on normal platelet function. | 1979 | Br. J. Haematol. | pmid:427045 |
| Friedman LS et al. | Cardiovascular and pulmonary effects of thromboxane B2 in the dog. | 1979 | Circ. Res. | pmid:428069 |
| Ciabattoni G et al. | Characterization of furosemide-induced activation of the renal prostaglandin system. | 1979 | Eur. J. Pharmacol. | pmid:393525 |
| Russell NH et al. | Thrombocytopathy in preleukaemia: association with a defect of thromboxane A2 activity. | 1979 | Br. J. Haematol. | pmid:570847 |
| Anhut H et al. | Prostaglandin D2 is the prevailing prostaglandin in the acute inflammatory exudate of urate arthritis in the chicken. | 1979 | Br. J. Pharmacol. | pmid:570865 |
| Davis TM et al. | Prostacyclin and thromboxane metabolites in diabetes. | 1979 | Lancet | pmid:90875 |
| Best L et al. | Effect of glucose on platelet thromboxane biosynthesis. | 1979 | Lancet | pmid:90876 |
| Jarabak J and Fried J | Comparison of substrate specificities of the human placental NAD- and NADP-linked 15-hydroxyprostaglandin dehydrogenases. | 1979 | Prostaglandins | pmid:42948 |
| Hassid A et al. | Prostaglandin synthesis in isolated rat kidney glomeruli. | 1979 | Proc. Natl. Acad. Sci. U.S.A. | pmid:286300 |
| Le Breton GC et al. | 13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor. | 1979 | Proc. Natl. Acad. Sci. U.S.A. | pmid:291066 |
| Boura AL and Murphy RD | Thromboxane B2 inhibits prostaglandin E2 inactivation by the rat isolated perfused lung. | 1978 Jul-Aug | Clin. Exp. Pharmacol. Physiol. | pmid:699382 |
| Davies GC et al. | Thromboxane B2 and fibrinopeptide A levels in platelet consumption and thrombosis. | 1978 | Surg Forum | pmid:401227 |
| Mitchell MD et al. | Possible role for prostacyclin in human parturition. | 1978 | Prostaglandins | pmid:373020 |
| Tai HH and Yuan B | Development of radioimmunoassay for thromboxane B2. | 1978 | Anal. Biochem. | pmid:567443 |
| Murota S and Morita I | Effect of prostaglandin I2 and related compounds on vascular permeability response in granuloma tissues. | 1978 | Prostaglandins | pmid:635221 |
| Powell WS and Solomon S | Biosynthesis of prostaglandins and thromboxane B2 by fetal lung homogenates. | 1978 | Prostaglandins | pmid:635224 |
| Tai HH et al. | Transformation of arachidonate into 6-oxoprostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 by sheep lung microsomal fraction. | 1978 | Biochem. J. | pmid:637853 |
| Murota SI et al. | Transformation of arachidonic acid into thromboxane B2 by the homogenates of activated macrophages. | 1978 | Biochim. Biophys. Acta | pmid:638172 |
| Mallen DN et al. | Structural verification of 15-oxo-13,14-dihydrothromboxane B2. | 1978 | Biomed. Mass Spectrom. | pmid:678616 |
| Morita I et al. | Characterization of thromboxane B2 and 6-ketoprostaglandin F alpha by combined gas chromatography and chemical-ionization mass spectrometry. | 1978 | J. Chromatogr. | pmid:681479 |
| Mitchell MD et al. | Production of thromboxane B2 by intra-uterine tissues from pregnant goats in vitro. | 1978 | J. Endocrinol. | pmid:681871 |
| Fitzpatrick FA et al. | An antiserum against 9,11-azo-15-hydroxyprosta-5,13-dienoic acid recognises and binds prostaglandin endoperoxides. | 1978 | Nature | pmid:652034 |
| Cerskus AL et al. | Effects of indomethacin and sulfinpyrazone on in vivo formation of thromboxane B2 and prostaglandin D2 during arachidonate infusion in rabbits. | 1978 | Thromb. Res. | pmid:653641 |
| Mitchell MD et al. | Thromboxane B2 in amniotic fluid before and during labour. | 1978 | Br J Obstet Gynaecol | pmid:656348 |
| Raz A et al. | Biosynthesis of thromboxane B2 and 12-L-hydroxy-5,8,10-heptadecatrienoic acid in human platelets. Evidence for a common enzymatic pathway. | 1978 | Eur. J. Biochem. | pmid:658053 |
| Salmon JA | A radioimmunoassay for 6-keto-prostaglandin F1alpha. | 1978 | Prostaglandins | pmid:663275 |
| Davidson EM et al. | The release of thromboxane B2 by rabbit peritoneal polymorphonuclear leucocytes [proceedings]. | 1978 | Br. J. Pharmacol. | pmid:667479 |
| Goldstein IM et al. | Thromboxane generation by human peripheral blood polymorphonuclear leukocytes. | 1978 | J. Exp. Med. | pmid:702055 |
| Anhut H et al. | Pharmacological modification of thromboxane and prostaglandin release in cardiac anaphylaxis. | 1978 | Prostaglandins | pmid:704912 |
| Nelson NA et al. | Synthesis of thromboxane B2 metabolites. | 1978 | Prostaglandins | pmid:704927 |
| Marion J and Wolfe LS | Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. | 1978 | Prostaglandins | pmid:704928 |
| Kitchen EA et al. | Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes. | 1978 | Prostaglandins | pmid:704931 |
| Sors H et al. | Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry. | 1978 | Prostaglandins | pmid:704933 |
| Turk J et al. | Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography. | 1978 | Prostaglandins | pmid:704934 |
| Raz A and Aharony D | Prostaglandin biosynthesis in platelets: demonstration and role of prostaglandin H2 leads to E2 isomerase. | 1978 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:705027 |
| Chang WC et al. | Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma. | 1978 | Biochem. Pharmacol. | pmid:619892 |
| Goetzl EJ and Gorman RR | Chemotactic and chemokinetic stimulation of human eosinophil and neutrophil polymorphonuclear leukocytes by 12-L-hydroxy-5,8,10-heptadecatrienoic acid (HHT). | 1978 | J. Immunol. | pmid:621391 |
| Mitchell MD et al. | Thromboxane B2 and human parturition: concentrations in the plasma and production in vitro. | 1978 | J. Endocrinol. | pmid:712300 |
| Yoshimoto T et al. | Selective inhibition of prostaglandin endoperoxide thromboxane isomerase by 1-carboxyalkylimidazoles. | 1978 | Prostaglandins | pmid:725083 |
| Anderson MW et al. | Kinetic studies on the conversion of prostaglandin endoperoxide PGH2 by thromboxane synthase. | 1978 | Prostaglandins | pmid:725086 |
| Mitchell MD et al. | Concentrations of thromboxane B2 in the maternal and foetal plasma of sheep during late pregnancy and induced parturition [proceedings]. | 1978 | J. Endocrinol. | pmid:731165 |
| Anhut H et al. | Release of 15-keto-13, 14-dihydro-thromboxane B2 and prostaglandin D2 during anaphylaxis as measured by radioimmunoassay. | 1978 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:740052 |
| McMillan RM et al. | Malonaldehyde formation in intact platelets is catalysed by thromboxane synthase. | 1978 | Biochem. J. | pmid:743261 |
| Chignard M et al. | Synthesis of thromboxane B2 in incubates of dog platelet-rich plasma with arachidonic acid and its inhibition by different drugs. | 1978 | Biochem. Biophys. Res. Commun. | pmid:743319 |
| Mitchell MD and Robinson JS | Concentrations of 6-oxo-prostaglandin F1 alpha and thromboxane B2 in the tracheal fluid of foetal sheep. | 1978 | J. Endocrinol. | pmid:744937 |
| Agradi E et al. | Influence of short term dietary supplementation of different lipids on aggregation and arachidonic acid metabolism in rabbit platelets. | 1978 | Prostaglandins | pmid:748984 |
| Fitzpatrick FA and Gorman RR | A comparison of imidazole and 9,11-azoprosta-5,13-dienoic acid. Two selective thromboxane synthetase inhibitors. | 1978 | Biochim. Biophys. Acta | pmid:629996 |
| Malik KU | Prostaglandin-mediated inhibition of the vasoconstrictor responses of the isolated perfused art splenic vasculature to adrenergic stimuli. | 1978 | Circ. Res. | pmid:27321 |
| Hamberg M et al. | A method for measurement of platelet regeneration in man. | 1978 | Prostaglandins Med | pmid:104315 |
| Roberts LJ et al. | Metabolism of thromboxane B2 in the monkey. | 1978 | J. Biol. Chem. | pmid:97291 |
| Mitchell MD et al. | Production of thromboxane B2 by the intra-uterine tissues from late pregnant Rhesus monkeys (Macaca mulatta) in vitro. | 1978 | J. Endocrinol. | pmid:101641 |
| Barac G | [Does thromboxane B2 influence renal blood flow? (proceedings)]. | 1978 | Arch. Int. Physiol. Biochim. | pmid:80176 |
| Engineer DM et al. | Modulation of slow-reacting substance of anaphylaxis and histamine release by prostacyclin and thromboxanes [proceedings]. | 1978 | J. Physiol. (Lond.) | pmid:81301 |
| Best LC et al. | Dipyridamole and platelet function. | 1978 | Lancet | pmid:81402 |
| Adcock JJ et al. | The mechanism of enhancement by fatty acid hydroperoxides of anaphylactic mediator release. | 1978 | Prostaglandins | pmid:81495 |
| Lagarde M et al. | Impairment of platelet thromboxane A2 generation and of the platelet release reaction in two patients with congenital deficiency of platelet cyclo-oxygenase. | 1978 | Br. J. Haematol. | pmid:205238 |
| Crawford A et al. | Rat osteogenic sarcoma cells: comparison of the effects of prostaglandins E1, E2, I2 (prostacyclin), 6-keto F1alpha and thromboxane B2 on cyclic AMP production and adenylate cyclase activity. | 1978 | Biochem. Biophys. Res. Commun. | pmid:212039 |
| Hyman AL et al. | Prostaglandins and the lung. | 1978 | Am. Rev. Respir. Dis. | pmid:339796 |
| Trang LE et al. | Levels of prostaglandins F2 alpha and E2 and thromboxane B2 in joint fluid in rheumatoid arthritis. | 1977 | Scand. J. Rheumatol. | pmid:929121 |
| Smith AG et al. | Gas-liquid chromatography-mass spectrometry of thromboxane B2 and its detection in semen and human aorta by selected ion monitoring. | 1977 | J. Chromatogr. | pmid:562354 |
| Abdel-Halim MS et al. | Identification of prostaglandin D2 as a major prostaglandin in homogenates of rat brain. | 1977 | Prostaglandins | pmid:594367 |
| Williams KI and Downing I | Prostaglandin and thromboxane production by rat decidual microsomes. | 1977 | Prostaglandins | pmid:594385 |
| Ali M et al. | Synthesis of thromboxane B2 and prostaglandins by bovine gastric mucosal microsomes. | 1977 | Prostaglandins | pmid:594386 |
| Wasserman MA and Griffin RL | Thromboxane B2--comparative bronchoactivity in experimental systems. | 1977 | Eur. J. Pharmacol. | pmid:590340 |
| Poyser NL | Identification of thromboxane B2 in guinea-pig uterine homogenates. | 1977 | Experientia | pmid:590434 |
| Fitzpatrick FA et al. | A radioimmunoassay for thromboxane B2. | 1977 | Anal. Biochem. | pmid:907115 |
| Murota SI et al. | The effects of thromboxane B2 and 6-ketoprostaglandin F1alpha on cultured fibroblasts. | 1977 | Biochim. Biophys. Acta | pmid:911847 |
| Roberts LJ et al. | Metabolism of thromboxane B2 in man. Identification of the major urinary metabolite. | 1977 | J. Biol. Chem. | pmid:914816 |
| Ali M et al. | Synthesis of prostaglandin D2 and thromboxane B2 by human platelets. | 1977 | Thromb. Res. | pmid:918907 |
| Burka JF and Garland LG | A possible modulatory role for prostacyclin (PGI2) INIgGa-induced release of slow-reacting substance of anaphylaxis in rats. | 1977 | Br. J. Pharmacol. | pmid:339980 |
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