Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cuiper LL et al. | Systemic and pulmonary hypertension after abrupt cessation of prostacyclin: role of thromboxane A2. | 1996 | J. Appl. Physiol. | pmid:8847301 |
| Nowak J et al. | Thromboxane metabolite excretion in patients with hand-arm vibration syndrome. | 1996 | Clin Physiol | pmid:8842572 |
| Stichtenoth DO et al. | Increased total body synthesis of prostacyclin in rats with adjuvant arthritis. | 1995 Nov-Dec | Prostaglandins | pmid:8838242 |
| Muller M and Sorrell TC | Inhibition of the human platelet cyclooxygenase response by the naturally occurring phenazine derivative, 1-hydroxyphenazine. | 1995 Nov-Dec | Prostaglandins | pmid:8838240 |
| Fylling AC et al. | Kinetic and structural evidence for the identification of 11-hydroxythromboxane B2 dehydrogenase as cytosolic aldehyde dehydrogenase. | 1995 Nov-Dec | Prostaglandins | pmid:8838239 |
| Meade CJ et al. | Pulmonary pharmacology of DT-TX 30 SE, a potent selective combined thromboxane synthetase inhibitor and receptor antagonist, in guinea pigs. | 1996 | Jpn. J. Pharmacol. | pmid:8835638 |
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| Mizugaki M et al. | Microdetermination of 11-dehydrothromboxane B3 in human urine by gas chromatography--selected-ion monitoring using (18O2) analogue as an internal standard. | 1995 | Rapid Commun. Mass Spectrom. | pmid:8829485 |
| Ishibashi M et al. | Identification of 11-dehydro-2,3-dinorthromboxane B3 in human urine based on the mass spectral properties of 11-dehydrothromboxane B3 and related compounds. | 1995 | Rapid Commun. Mass Spectrom. | pmid:8829476 |
| Mitten LA et al. | Phenylbutazone increases right atrial pressure and heart rate of running horses. | 1996 | J. Appl. Physiol. | pmid:8828679 |
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| Wagner RS et al. | Activation of thromboxane A2 receptors alters lipopolysaccharide-induced adherence of THP-1 cells. | 1996 | Shock | pmid:8821102 |
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| González ET et al. | Prostanoid modulation of glucose transport in isolated diabetic rat uterus. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8804128 |
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| Lewy RI et al. | Intravenous heparin initiates in-vivo synthesis and release of thromboxane in angina pectoris. | 1979 | Lancet | pmid:87990 |
| Morrow JD et al. | Nonenzymatic free radical-catalyzed generation of thromboxane-like compounds (isothromboxanes) in vivo. | 1996 | J. Biol. Chem. | pmid:8798513 |
| Fox GA et al. | Cyclooxygenase inhibition and vascular reactivity in a rat model of hyperdynamic sepsis. | 1996 | J. Cardiovasc. Pharmacol. | pmid:8797133 |
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| Collins CE et al. | Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791957 |
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| Raptopoulos D et al. | The effect of xylazine on plasma thromboxane B2 concentration in sheep. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8789696 |
| Bell SJ et al. | Dietary fish oil and cytokine and eicosanoid production during human immunodeficiency virus infection. | 1996 Jan-Feb | JPEN J Parenter Enteral Nutr | pmid:8788262 |
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| Uhlig S et al. | Cyclooxygenase-2-dependent bronchoconstriction in perfused rat lungs exposed to endotoxin. | 1996 | Mol. Med. | pmid:8784790 |
| Gennaro M et al. | Perfluorocarbon emulsion prevents eicoasanoid release in skeletal muscle ischemia and reperfusion. | 1996 | Cardiovasc Surg | pmid:8782946 |
| Nabe T et al. | Sephadex G-200-induced eosinophil infiltration into airways in non-sensitized and sensitized guinea pigs, and responsiveness of the cells to stimuli in vitro. | 1996 | Jpn. J. Pharmacol. | pmid:8774762 |
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| Madan ZM and Sainani GS | Effect of aspirin treatment on plasma levels of keto PGF 1 alpha and thromboxane B2. | 1995 | J Assoc Physicians India | pmid:8773058 |
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| Closa D et al. | Hepatic involvement in pancreatitis-induced lung damage. | 1996 | Am. J. Physiol. | pmid:8772495 |
| Abernathy VJ et al. | C-reactive protein inhibits increased pulmonary vascular permeability induced by fMLP in isolated rabbit lungs. | 1996 | Am. J. Physiol. | pmid:8770090 |
| Shirabe K et al. | Inhibition of thromboxane A2 activity during warm ischemia of the liver. | 1996 | J. Surg. Res. | pmid:8769950 |
| Qiu BS et al. | Protection by recombinant human interleukin-11 against experimental TNB-induced colitis in rats. | 1996 | Dig. Dis. Sci. | pmid:8769290 |
| Hrboticky N et al. | Linoleic acid esterified in low density lipoprotein serves as substrate for increased arachidonic acid synthesis in differentiating monocytic cells. | 1996 | Biochim. Biophys. Acta | pmid:8765140 |
| Fleisch JH et al. | Recombinant human secretory phospholipase A2 released thromboxane from guinea pig bronchoalveolar lavage cells: in vitro and ex vivo evaluation of a novel secretory phospholipase A2 inhibitor. | 1996 | J. Pharmacol. Exp. Ther. | pmid:8764358 |