Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Edema, Cardiac D004489 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Radiculopathy D011843 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Bluetongue D001819 1 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Heart Septal Defects D006343 2 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Weil Disease D014895 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Keith JC et al. Beneficial effects of U-63,557A, a thromboxane synthetase inhibitor, in an ovine model of pregnancy-induced hypertension. 1987 Am. J. Obstet. Gynecol. pmid:3605254
Jouppila P et al. Ritodrine infusion during late pregnancy: effects on fetal and placental blood flow, prostacyclin, and thromboxane. 1985 Am. J. Obstet. Gynecol. pmid:3885740
Sørensen JD et al. Effects of fish oil supplementation in the third trimester of pregnancy on prostacyclin and thromboxane production. 1993 Am. J. Obstet. Gynecol. pmid:8456902
Fantone JC et al. Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. 1984 Am. J. Pathol. pmid:6324595
Cybulsky AV et al. A role for thromboxane in complement-mediated glomerular injury. 1987 Am. J. Pathol. pmid:3111267
Zoja C et al. Selective inhibition of platelet thromboxane generation with low-dose aspirin does not protect rats with reduced renal mass from the development of progressive disease. 1989 Am. J. Pathol. pmid:2497648
Lundberg C et al. C5a-induced hemodynamic and hematologic changes in the rabbit. Role of cyclooxygenase products and polymorphonuclear leukocytes. 1987 Am. J. Pathol. pmid:3115110
Stimler NP and O'Flaherty JT Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues. 1983 Am. J. Pathol. pmid:6624879
Woods LW et al. Structural and biochemical changes in lungs of 3-methylindole-treated rats. 1993 Am. J. Pathol. pmid:8424451
Diamond JR et al. Altered functional characteristics of rat macrophages during nephrosis. Synergistic effects of hypercholesterolemia. 1989 Am. J. Pathol. pmid:2801885
Cook HT et al. Functional characteristics of macrophages in glomerulonephritis in the rat. O2- generation, MHC class II expression, and eicosanoid synthesis. 1989 Am. J. Pathol. pmid:2537019
Mundie TG et al. Byssinosis: Release of prostaglandins, thromboxane, and 5-hydroxytryptamine in bronchopulmonary lavage fluid after inhalation of cotton dust extracts. 1985 Am. J. Pathol. pmid:3966532
Bertani T et al. Tumor necrosis factor induces glomerular damage in the rabbit. 1989 Am. J. Pathol. pmid:2916653
Hamilton J et al. Platelet interaction with a pancreatic ascites tumor. 1986 Am. J. Pathol. pmid:3510553
Nanji AA et al. Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2. 1993 Am. J. Pathol. pmid:8382006
Schuette AH et al. Effect of lung thromboxane generation on regional blood flow during sheep bypass. 1982 Am. J. Physiol. pmid:7065206
Yamamoto S et al. Endothelin causes portal and pulmonary hypertension in porcine endotoxemic shock. 1997 Am. J. Physiol. pmid:9087598
Düsing R et al. Dietary linoleic acid deprivation: effects on blood pressure and PGI2 synthesis. 1983 Am. J. Physiol. pmid:6337507
Olson KR et al. Cardiovascular effects of homologous bradykinin in rainbow trout. 1997 Am. J. Physiol. pmid:9140009
Strand JC et al. Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. 1981 Am. J. Physiol. pmid:6787931
Peterson MB et al. Thromboxane mediates acute pulmonary hypertension in sheep extracorporeal perfusion. 1982 Am. J. Physiol. pmid:7051860
Nishijima MK et al. Effect of naloxone and ibuprofen on organ blood flow during endotoxic shock in pig. 1988 Am. J. Physiol. pmid:3394818
Katusić ZS et al. Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery. 1993 Am. J. Physiol. pmid:8456988
Olson NC et al. Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs. 1993 Am. J. Physiol. pmid:8460710
Chang SW and Ohara N Increased pulmonary vascular permeability in rats with biliary cirrhosis: role of thromboxane A2. 1993 Am. J. Physiol. pmid:8460713
Amsterdam EA et al. Contractile actions of C5a on isolated porcine myocardium. 1992 Am. J. Physiol. pmid:1357981
Dobner P and Engelmann B Low-density lipoproteins supply phospholipid-bound arachidonic acid for platelet eicosanoid production. 1998 Am. J. Physiol. pmid:9814996
Stephenson AH et al. 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. 1998 Am. J. Physiol. pmid:9688901
Perlman MB et al. Ibuprofen prevents thrombin-induced lung vascular injury: mechanism of effect. 1987 Am. J. Physiol. pmid:3030141
Stenmark KR et al. Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension. 1985 Am. J. Physiol. pmid:3923843
Scharschmidt LA et al. Angiotensin II and eicosanoids in the control of glomerular size in the rat and human. 1986 Am. J. Physiol. pmid:2936254
Wagerle LC et al. Effect of dexamethasone on cerebral prostanoid formation and pial arteriolar reactivity to CO2 in newborn pigs. 1991 Am. J. Physiol. pmid:1901460
Benigni A et al. Renal metabolism and urinary excretion of thromboxane B2 in the rat. 1989 Am. J. Physiol. pmid:2750927
Hollenberg SM et al. Eicosanoid production by human aortic endothelial cells in response to endothelin. 1994 Am. J. Physiol. pmid:7810729
Garfield RE et al. Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. 1980 Am. J. Physiol. pmid:7369350
Townsley MI et al. Pulmonary embolism: analysis of endothelial pore sizes in canine lung. 1988 Am. J. Physiol. pmid:3189571
Morel DR et al. Leukotrienes, thromboxane A2, and prostaglandins during systemic anaphylaxis in sheep. 1991 Am. J. Physiol. pmid:1716064
Klotman PE et al. Thromboxane synthetase inhibition improves function of hydronephrotic rat kidneys. 1986 Am. J. Physiol. pmid:3456211
Himmelstein SI and Klotman PE The role of thromboxane in two-kidney, one-clip Goldblatt hypertension in rats. 1989 Am. J. Physiol. pmid:2527469
Chen L et al. Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. 1997 Am. J. Physiol. pmid:9362253
Bradley LM et al. Circulatory effects of PAF-acether in newborn piglets. 1989 Am. J. Physiol. pmid:2912183
Coceani F et al. Prostaglandin E2 and thromboxane B2 in cerebrospinal fluid of afebrile and febrile cat. 1983 Am. J. Physiol. pmid:6574712
Longhurst JC et al. Increased concentration of leukotriene B4 but not thromboxane B2 in intestinal lymph of cats during brief ischemia. 1992 Am. J. Physiol. pmid:1317130
Kauser K and Rubanyi GM Gender difference in bioassayable endothelium-derived nitric oxide from isolated rat aortae. 1994 Am. J. Physiol. pmid:7810731
Stahl RA et al. High protein intake stimulates glomerular prostaglandin formation in remnant kidneys. 1987 Am. J. Physiol. pmid:3473940
Lorenz RR and Vanhoutte PM Prejunctional adrenergic inhibition by aggregating platelets in canine blood vessels. 1985 Am. J. Physiol. pmid:4037113
Farman N et al. PGE2, PGF2 alpha, 6-keto-PGF1 alpha, and TxB2 synthesis along the rabbit nephron. 1987 Am. J. Physiol. pmid:3101513
Raj JU and Chen P Role of eicosanoids in hypoxic vasoconstriction in isolated lamb lungs. 1987 Am. J. Physiol. pmid:2820247
Miyazaki Y et al. Selective turnover of sarcolemmal phospholipids with lethal cardiac myocyte injury. 1990 Am. J. Physiol. pmid:2382705
Dunham BM et al. Role of prostaglandins in positive end-expiratory pressure-induced negative inotropism. 1981 Am. J. Physiol. pmid:7034549