Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Radiculopathy D011843 1 associated lipids
Erythromelalgia D004916 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Intracranial Hemorrhage, Hypertensive D020299 1 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Atrial Premature Complexes D018880 1 associated lipids
Bluetongue D001819 1 associated lipids
Gastric Dilatation D013271 1 associated lipids
Latex Hypersensitivity D020315 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Edema, Cardiac D004489 1 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Heart Septal Defects D006343 2 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Weil Disease D014895 2 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Yu J and Hu WS [Effects of neferine on platelet aggregation in rabbits]. 1997 Yao Xue Xue Bao pmid:11243209
Hellyer PW et al. Effect of NG-nitro-L-arginine-methyl-ester on cardiopulmonary function and biosynthesis of cyclooxygenase products during porcine endotoxemia. 1997 Crit. Care Med. pmid:9201060
Nanji AA et al. Thromboxane inhibitors attenuate pathological changes in alcoholic liver disease in the rat. 1997 Gastroenterology pmid:8978360
Berg J et al. Isoenzyme-specific cyclooxygenase inhibitors: a whole cell assay system using the human erythroleukemic cell line HEL and the human monocytic cell line Mono Mac 6. 1997 J Pharmacol Toxicol Methods pmid:9279772
Mori TA et al. Interactions between dietary fat, fish, and fish oils and their effects on platelet function in men at risk of cardiovascular disease. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9081682
Hsieh YZ and Kuo KL Analysis of prostaglandins by micellar electrokinetic capillary chromatography. 1997 J Chromatogr A pmid:9084156
Todd MK et al. Comparison of methods for evaluating exercise-induced changes in thromboxane B2 and beta-thromboglobulin. 1997 Med Sci Sports Exerc pmid:9140910
Bishop-Bailey D et al. Characterization of the induction of nitric oxide synthase and cyclo-oxygenase in rat aorta in organ culture. 1997 Br. J. Pharmacol. pmid:9146896
Shinohara M et al. [Responses to surgical stress in blood coagulation and fibrinolysis, platelet counts and thromboxane B2 after esophageal cancer operation]. 1997 Rinsho Byori pmid:9121003
Cheng Z et al. Pharmacokinetic and pharmacodynamic studies on phenylbutazone and oxyphenbutazone in goats. 1997 Vet. Rec. pmid:9123796
Tang QZ et al. [Effect of buyang huanwu decoction on platelet function and fibrinolytic activity of unstable angina pectoris patients]. 1997 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:10322871
Chen SX et al. [Effects of tetramethylpyrazine on platelet functions of advanced cases of lung carcinoma]. 1997 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:10322873
Chong ZZ and Feng YP Effects of dl-3-n-butylphthalide on production of TXB2 and 6-keto-PGF1 alpha in rat brain during focal cerebral ischemia and reperfusion. 1997 Zhongguo Yao Li Xue Bao pmid:10322905
Carty TJ et al. Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models. 1997 Inflamm. Res. pmid:9197987
Keen HL et al. Thromboxane is required for full expression of angiotensin hypertension in rats. 1997 Hypertension pmid:9039120
Rodwell LT et al. Effect of inhaled frusemide and oral indomethacin on the airway response to hypertonic saline challenge in asthmatic subjects. 1997 Thorax pmid:9039247
Nanji AA et al. Enhanced cyclooxygenase-2 gene expression in alcoholic liver disease in the rat. 1997 Gastroenterology pmid:9041257
Watanabe A et al. Effect of TYB-2285 on lung anaphylaxis in actively sensitized rats. 1997 Gen. Pharmacol. pmid:9013209
Lewis DA et al. Production of endothelium-derived factors from sodded expanded polytetrafluoroethylene grafts. 1997 J. Vasc. Surg. pmid:9013924
Liu CZ and Huang TF Crovidisin, a collagen-binding protein isolated from snake venom of Crotalus viridis, prevents platelet-collagen interaction. 1997 Arch. Biochem. Biophys. pmid:9016825
Yeh SL et al. Effects of n-3 and n-6 fatty acids on plasma eicosanoids and liver antioxidant enzymes in rats receiving total parenteral nutrition. 1997 Nutrition pmid:9058445
Feng J et al. Effects of tetramethylpyrazine on the release of PGI2 and TXA2 in the hypoxic isolated rat heart. 1997 Mol. Cell. Biochem. pmid:9059992
Hansen TN and Brockbank KG Increased platelet aggregation due to chilling to 20 degrees C is not related to increased sensitivity to agonists. 1997 Transfusion pmid:9225932
Bräutigam R et al. Arachidonic acid of platelet phospholipids is decreased after extracorporeal removal of plasma low density lipoproteins in patients with familial hypercholesterolemia. 1997 Atherosclerosis pmid:9180250
Rautanen M et al. Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs. 1997 Crit. Care Med. pmid:9233750
Müller M In vivo measurement of interstitial TxB2-concentrations in skeletal muscle during ischemia and reperfusion. 1997 Adv. Exp. Med. Biol. pmid:9561122
Arbogast E et al. Intrauterine eicosanoid production in uncomplicated and hypertensive pregnancies: alterations of placental 12-hydroxyeicosatetraenoic acid. 1997 Adv. Exp. Med. Biol. pmid:9561182
Byrne A et al. Continued thromboxane A2 formation despite administration of a platelet glycoprotein IIb/IIIa antagonist in patients undergoing coronary angioplasty. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9409315
Gerdemann R et al. [Effect of flunixin meglumine on plasma prostanoid concentrations in horses with colic in the perioperative period]. 1997 DTW. Dtsch. Tierarztl. Wochenschr. pmid:9410724
Kobayashi T et al. Changes in platelet calcium concentration by thromboxane A2 stimulation in patients with nephrotic syndrome of childhood. 1997 Nephron pmid:9375825
Chavali SR et al. Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin. 1997 Int. Arch. Allergy Immunol. pmid:9338609
Neupert W et al. Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases. 1997 Br. J. Pharmacol. pmid:9351505
Zahavi M and Zahavi J Concomitant in vitro platelet hypofunction and increased thromboxane B2 (TXB2) generation and enhanced in vivo platelet activation. A distinct syndrome in thrombosis? 1997 Eur. J. Haematol. pmid:9338626
Supanz S et al. Effects of the novel thromboxane (TXA2) receptor antagonist linotroban on inulin and para-aminohippuric acid clearances in the conscious male and female rat. 1997 Arzneimittelforschung pmid:9342416
Tulppala M et al. Low-dose aspirin in prevention of miscarriage in women with unexplained or autoimmune related recurrent miscarriage: effect on prostacyclin and thromboxane A2 production. 1997 Hum. Reprod. pmid:9262298
Nanji AA et al. Alterations in thromboxane synthase and thromboxane A2 receptors in experimental alcoholic liver disease. 1997 J. Pharmacol. Exp. Ther. pmid:9262373
Tu Y et al. Effect of intra-arachnoid space perfusion on thromboxane A and prostacycline in experimental spinal cord injury. 1997 J. Tongji Med. Univ. pmid:9639784
De La Cruz JP et al. Effects of S-adenosyl-L-methionine on platelet thromboxane and vascular prostacyclin. 1997 Biochem. Pharmacol. pmid:9264331
Li S and Tian H [Oral low-dose magnesium gluconate preventing pregnancy induced hypertension]. 1997 Zhonghua Fu Chan Ke Za Zhi pmid:9642379
Gresele P et al. Platelet activation markers in patients with peripheral arterial disease--a prospective comparison of different platelet function tests. 1997 Thromb. Haemost. pmid:9423790
Famaey JP In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview. 1997 Inflamm. Res. pmid:9427063
Baskett A et al. Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses. 1997 Am. J. Vet. Res. pmid:9361895
Shen ZQ et al. Inhibitory effects of copper-aspirin complex on platelet aggregation. 1997 Zhongguo Yao Li Xue Bao pmid:10072923
Barton MH et al. Effects of pentoxifylline infusion on response of horses to in vivo challenge exposure with endotoxin. 1997 Am. J. Vet. Res. pmid:9361896
Zeng S and Guo ZG Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine. 1997 Zhongguo Yao Li Xue Bao pmid:10072970
Kraft M et al. The effect of salmeterol on nocturnal symptoms, airway function, and inflammation in asthma. 1997 Chest pmid:9149578
Rocha FA et al. PAF modulates eicosanoids and TNF release in immune-complex arthritis in rats. 1997 J Lipid Mediat Cell Signal pmid:9101418
Sun ZT et al. [Clinical and experimental study on treating bronchial asthma with xingbei granule]. 1997 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9863090
Zhang XY and Qian XM [Clinical study of sudden deafness treated with method of integrated traditional Chinese and Western medicine]. 1997 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9863112
Wu JX et al. [Effects and mechanism of emodin and sandostatin on pancreatic ischemia in acute haemorrhagic necrotizing pancreatitis]. 1997 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9863132
Hu DH et al. [Effects of hypoxia and anisodamine on products of TXA2 and PGI2 in cultured intra-pulmonary arteriolar smooth muscle cells]. 1997 Sheng Li Xue Bao pmid:9863190
Li HP et al. [The relationship between the activity of phospholipase A2 and acute hypoxic pulmonary arterial pressure]. 1997 Sheng Li Xue Bao pmid:9863193
Oosaki R et al. Urinary excretion of leukotriene E4 and 11-dehydrothromboxane B2 in patients with spontaneous asthma attacks. 1997 Int. Arch. Allergy Immunol. pmid:9414142
Fenner H Differentiating among nonsteroidal antiinflammatory drugs by pharmacokinetic and pharmacodynamic profiles. 1997 Semin. Arthritis Rheum. pmid:9219317
Teng CM et al. Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man. 1997 J. Pharm. Pharmacol. pmid:9255715
De la Cruz JP et al. Effect of erythrocytes and prostacyclin production in the effect of fructose and sorbitol on platelet activation in human whole blood in vitro. 1997 Thromb. Res. pmid:9219331
Abate A et al. Inhibition of mediator release from anaphylactic guinea pig hearts by the novel phospholipase A2 inhibitor 3-(4-octadecylbenzoyl) acrylic acid. 1997 Inflamm. Res. pmid:9297549
Slepko N et al. Reorientation of prostanoid production accompanies "activation" of adult microglial cells in culture. 1997 J. Neurosci. Res. pmid:9260740
Davì G et al. Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease. 1997 Circulation pmid:9236419
Johnson RD et al. Aspirin induces increased expression of both prostaglandin H synthase-1 and prostaglandin H synthase-2 in cultured human placental trophoblast. 1997 Am. J. Obstet. Gynecol. pmid:9240586
Fujinishi A et al. Effects of nisoldipine on cytosolic calcium, platelet aggregation, and coagulation/fibrinolysis in patients with coronary artery disease. 1997 Angiology pmid:9194537
Freese R and Mutanen M Alpha-linolenic acid and marine long-chain n-3 fatty acids differ only slightly in their effects on hemostatic factors in healthy subjects. 1997 Am. J. Clin. Nutr. pmid:9280178
Cook ME et al. Comparative effects of nabumetone, sulindac, and ibuprofen on renal function. 1997 J. Rheumatol. pmid:9195523
Hato T et al. Outside-in signaling from integrin alpha IIb beta 3 into platelets in the absence of agonist-induced signaling. 1997 Int. J. Hematol. pmid:9195778
Hishinuma T et al. Microdetermination of the thromboxane B3 gas chromatography-selected-ion monitoring using [18O]thromboxane B3 as an internal standard. 1997 Prostaglandins pmid:9261859
Zheng NX et al. Pharmacokinetic-pharmacodynamic modelling of DP-1904, a novel thromboxane synthetase inhibitor in rabbits, based on an indirect response model. 1996 Oct-Dec Eur J Drug Metab Pharmacokinet pmid:9074892
Pacchiarini L et al. In vitro effect of reduced glutathione on platelet function. 1996 Nov-Dec Haematologica pmid:9009436
Miyahara T et al. Specific neutrophil elastase inhibitor does not attenuate acute lung injury induced by air embolism in awake sheep. 1996 Nov-Dec Exp. Lung Res. pmid:8979046
Bell SJ et al. Dietary fish oil and cytokine and eicosanoid production during human immunodeficiency virus infection. 1996 Jan-Feb JPEN J Parenter Enteral Nutr pmid:8788262
Yan Y et al. [Study on mechanism of eye-signs in blood stasis syndrome]. 1996 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9206243
Gu YJ et al. Leukocyte depletion results in improved lung function and reduced inflammatory response after cardiac surgery. 1996 J. Thorac. Cardiovasc. Surg. pmid:8751518
Cuzzolin L et al. Effect of single and repeated doses of a new nitroderivative of acetylsalicylic acid on platelet TXA2 production in rats. 1996 Life Sci. pmid:8786689
Vaskonen T et al. Interrelationships between salt and fish oil in stroke-prone spontaneously hypertensive rat. 1996 Blood Press. pmid:8790929
Izaki S et al. Platelet-activating factor and arachidonic acid metabolites in psoriatic inflammation. 1996 Br. J. Dermatol. pmid:8763425
Fleisch JH et al. Recombinant human secretory phospholipase A2 released thromboxane from guinea pig bronchoalveolar lavage cells: in vitro and ex vivo evaluation of a novel secretory phospholipase A2 inhibitor. 1996 J. Pharmacol. Exp. Ther. pmid:8764358
Nosál R et al. The H1-histamine antagonist Dithiaden inhibits human platelets in vitro. 1996 Inflamm. Res. pmid:8696916
Taylor PM et al. Pharmacodynamics and enantioselective pharmacokinetics of carprofen in the cat. 1996 Res. Vet. Sci. pmid:8685536
Janssen PL et al. Consumption of ginger (Zingiber officinale roscoe) does not affect ex vivo platelet thromboxane production in humans. 1996 Eur J Clin Nutr pmid:8933126
Klosterhalfen B et al. Influence of heat shock protein 70 and metallothionein induction by zinc-bis-(DL-hydrogenaspartate) on the release of inflammatory mediators in a porcine model of recurrent endotoxemia. 1996 Biochem. Pharmacol. pmid:8937427
Stein CM et al. Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma. 1996 Arthritis Rheum. pmid:8670323
Matsumoto K et al. Role of thromboxane-A2 and cholinergic mechanisms in bronchoconstriction induced by cigarette smoke in guinea-pigs. 1996 Eur. Respir. J. pmid:8980955
Li F et al. [Effects of frostbite on some factors of blood coagulation system in rats under hypoxia]. 1996 Space Med Med Eng (Beijing) pmid:11539914
Garvin PJ et al. Evaluation of the thromboxane A2 synthetase inhibitor OKY-046 in a warm ischemia-reperfusion rat model. 1996 Transplantation pmid:8633364
Leung LK and Glauert HP Reduction of the concentrations of prostaglandins E2 and F2alpha, and thromboxane B2 in cultured rat hepatocytes treated with the peroxisome proliferator ciprofibrate. 1996 Toxicol. Lett. pmid:8644126
Morioka K et al. Leukocyte and platelet depletion with a blood cell separator: effects on lung injury after cardiac surgery with cardiopulmonary bypass. 1996 J. Thorac. Cardiovasc. Surg. pmid:8551788
Siler-Khodr TM et al. Dose-related action of estradiol on placental prostanoid prediction. 1996 Prostaglandins pmid:8873234
Kotuliaková K et al. Human polymorphonuclear leukocytes: effect of chloroquine on aggregation, arachidonic acid liberation and thromboxane B2 generation. 1996 Gen. Physiol. Biophys. pmid:9248834
Xiao X et al. Effect of captopril on renal hemodynamics and renal prostaglandins in early type II diabetic patients with normo-or microalbuminuria. 1996 Chin. Med. Sci. J. pmid:9387403
Sang Y et al. [Effects of tangshenkang capsule on diabetic nephropathy]. 1996 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:9387731
Tsunomori M et al. 15-Hydroperoxyeicosapentaenoic acid inhibits arachidonic acid metabolism in rabbit platelets more potently than eicosapentaenoic acid. 1996 Biochim. Biophys. Acta pmid:8679681
Takase B et al. Arachidonic acid metabolites in acute myocardial infarction. 1996 Angiology pmid:8686958
Carbajal D et al. Possible cytoprotective mechanism in rats of D-002, an anti-ulcerogenic product isolated from beeswax. 1996 J. Pharm. Pharmacol. pmid:8887738
Nowak J et al. Thromboxane metabolite excretion in patients with hand-arm vibration syndrome. 1996 Clin Physiol pmid:8842572
Baenkler HW et al. Eicosanoids from biopsy of normal and polypous nasal mucosa. 1996 Rhinology pmid:8938887
Quinn JV et al. Evaluation of enzyme-linked immunosorbent assays for quantitation of eicosanoid mediators of sepsis syndrome. 1996 Shock pmid:8856849
Reale M et al. Human recombinant interleukin-1 beta induces thromboxane A2 release in polymorphonuclear leukocytes, macrophages and platelets: effect of IL-1 receptor antagonist. 1996 Mol. Cell. Biochem. pmid:8858567
Bordia T et al. An evaluation of garlic and onion as antithrombotic agents. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8860105
Meenan J et al. Lexipafant (BB-882), a platelet activating factor receptor antagonist, ameliorates mucosal inflammation in an animal model of colitis. 1996 Eur J Gastroenterol Hepatol pmid:8823572
Zhen ZY et al. Experimental study on microthrombi and myocardial injuries. 1996 Microvasc. Res. pmid:8812763
Pace-Asciak CR et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. 1996 Clin. Chim. Acta pmid:8814965