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Antiplatelet activity of BRX-018, (6aS,cis)-malonic acid 3-acetoxy-6a9-bis-(2-methoxycarbonyl-acetoxy)-6,6a,7,11b-tetrahydro-indeno[2,1-c]chromen-10-yl ester methylester. |
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Thromb. Res. |
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Vaporized perfluorohexane attenuates ventilator-induced lung injury in isolated, perfused rabbit lungs. |
2005 |
Anesthesiology |
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[Insulin resistance and effects of intravenous acute saline load on renal production of prostaglandin I2 and thromboxane A2 in salt-sensitive hypertensive patients]. |
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Bradykinin B2 receptor antagonist FR173657 ameliorates small bowel ischemia-reperfusion injury in dogs. |
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Streptococcus sanguis-induced platelet activation involves two waves of tyrosine phosphorylation mediated by FcgammaRIIA and alphaIIbbeta3. |
2005 |
Thromb. Haemost. |
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Cigarette smoking is associated with increased circulating proinflammatory and procoagulant markers in patients with chronic coronary artery disease: effects of aspirin treatment. |
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Am. Heart J. |
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Carvedilol--a beta-blocker with considerable antiaggregatory effect on human blood platelets. |
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Kidney Int. |
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Therapeutic effects and possible mechanisms of a snake venom preparation in the fibrotic rat liver. |
2005 |
Dig. Dis. Sci. |
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Increased phospholipase A2 and thromboxane but not prostacyclin production by placental trophoblast cells from normal and preeclamptic pregnancies cultured under hypoxia condition. |
2005 |
Placenta |
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Bile duct ligation induced acute inflammation up-regulates cyclooxygenase-2 content and PGE2 release in guinea pig gallbladder smooth muscle cell cultures. |
2005 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Nakamura K et al. |
Influence of preoperative administration of omega-3 fatty acid-enriched supplement on inflammatory and immune responses in patients undergoing major surgery for cancer. |
2005 |
Nutrition |
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2-(2-Br-phenyl)-8-methoxy-benzoxazinone (HPW-RX2), a direct thrombin inhibitor with a suppressive effect on thromboxane formation in platelets. |
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Eur. J. Pharmacol. |
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Virgin Olive Oil Study (VOLOS): vasoprotective potential of extra virgin olive oil in mildly dyslipidemic patients. |
2005 |
Eur J Nutr |
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Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ mobilization. |
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J. Pharmacol. Exp. Ther. |
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[Influence of Minkeqing oral liquid on IL-6, IL-8, ET-1, TX-B2 in blood and to observe bronchoalveolar lavage fluid of the rat with inhalating ovalbumin]. |
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Platelet activation in patients with colorectal cancer. |
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Prostaglandins Leukot. Essent. Fatty Acids |
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Biological assessment of aspirin efficacy on healthy individuals: heterogeneous response or aspirin failure? |
2005 |
Stroke |
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Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism. |
2005 |
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Blood pressure circadian rhythm and endothelial function in heavy smokers: acute effects of transdermal nicotine. |
2005 |
J Clin Hypertens (Greenwich) |
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[The changes of some vasoactive substances after operation in patients with obstructive sleep apnea-hypopnea syndrome]. |
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Inhibition of thromboxane biosynthesis by triflusal in type 2 diabetes mellitus. |
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Atherosclerosis |
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Enzymologic and pharmacologic profile of loxoprofen sodium and its metabolites. |
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[Synthesis of 2-, 4- and 5-(2-alkylcarbamoyl-1-methylvinyl)-7-alkyloxybenzo[b]furans and their leukotriene B4 receptor antagonistic activity]. |
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Improvement of age-related endothelial dysfunction by simvastatin: effect on NO and COX pathways. |
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Captopril effect on prostaglandin E2, thromboxane B2 and proteinuria in lupus nephritis patients. |
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Inflammopharmacology |
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Comparative study of anti-inflammatory and ulcerogenic activities of different cyclo-oxygenase inhibitors. |
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Inflammopharmacology |
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Mechanisms involved in the antiplatelet activity of ketamine in human platelets. |
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11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. |
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Transdermal hormone replacement therapy and Doppler findings in normal and overweight postmenopausal patients. |
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Treatment of unstable angina pectoris with modified nuan gan jian--a report of 33 cases. |
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Effects of d-003, a new substance purified from sugar cane wax, on platelet aggregation and plasma levels of arachidonic acid metabolites in healthy volunteers. |
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The ingestion of Ginkgo biloba extract (EGb 761) inhibits arachidonic acid-mediated platelet aggregation and thromboxane B2 production in healthy volunteers. |
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J Herb Pharmacother |
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Effect of red clover isoflavones on cox-2 activity in murine and human monocyte/macrophage cells. |
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Nutr Cancer |
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Antithrombotic effects of FK419, a novel nonpeptide platelet GPIIb/IIIa antagonist, in a guinea pig photochemically induced middle cerebral artery thrombosis model: comparison with ozagrel and argatroban. |
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J. Pharmacol. Exp. Ther. |
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[Effects of effective component from "qing kai ling" on endothelial cell of microvessel in MCAO rats]. |
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Prothrombotic responses to exercise are little influenced by clopidogrel treatment. |
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Terms and conditions: semantic complexity and aspirin resistance. |
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Circulation |
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[Clinical study on relationship between sluggishness of lung-defensive qi and levels of vasoactive intestinal polypeptide and thromboxane B2]. |
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Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans. |
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[Influence of single leaf Asarum himalaicum on renal function of rabbits]. |
2004 |
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Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. |
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Obes. Res. |
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Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies. |
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Br. J. Pharmacol. |
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Effect of prostaglandins against alloxan-induced cytotoxicity to insulin secreting insulinoma RIN cells in vitro. |
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Prostaglandins Leukot. Essent. Fatty Acids |
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Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms. |
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Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis. |
2004 |
Arthritis Res. Ther. |
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Measurement of platelet arachidonic acid metabolism. |
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Inhaled cornstarch glove powder increases latex-induced airway hyper-sensitivity in guinea-pigs. |
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Clin. Exp. Allergy |
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[Detection of thromboxane B2, 6-keto-prostaglandin F1alpha and anticardiolipin antibody in patients with obstructive sleep apnea-hypopnea syndrome]. |
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Meloxicam does not affect the antiplatelet effect of aspirin in healthy male and female volunteers. |
2004 |
J Clin Pharmacol |
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Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs. |
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Coron. Artery Dis. |
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Short-term prevention of thromboembolic complications in patients with atrial fibrillation with aspirin plus clopidogrel: the Clopidogrel-Aspirin Atrial Fibrillation (CLAAF) pilot study. |
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[Some mechanisms of the development of endothelial disfunction in aging]. |
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Fiziol Zh |
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Acetaldehyde induces histamine release from human airway mast cells to cause bronchoconstriction. |
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Int. Arch. Allergy Immunol. |
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Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs. |
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J. Pharm. Pharmacol. |
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Effects of thiol antioxidant on reduced nicotinamide adenine dinucleotide phosphate oxidase in hypertensive Dahl salt-sensitive rats. |
2004 |
Free Radic. Biol. Med. |
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The effect of general anesthesia and abdominal surgery upon plasma thromboxane B concentrations in horses. |
2004 |
Vet Anaesth Analg |
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Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. |
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Equine Vet. J. |
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Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism. |
2004 |
J. Pharmacol. Exp. Ther. |
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Experimental evidence of a potentially increased thrombo-embolic disease risk by domestic electromagnetic field exposure. |
2004 |
Bioelectromagnetics |
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Aspirin resistance and diabetic angiopathy: back to the future. |
2004 |
Thromb. Res. |
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Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. |
2004 |
Circ. Res. |
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Inhibition of platelet aggregation by polyaspartoyl L-arginine and its mechanism. |
2004 |
Acta Pharmacol. Sin. |
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Inhibition of IL-6, TNF-alpha, and cyclooxygenase-2 protein expression by prostaglandin E2-induced IL-10 in bone marrow-derived dendritic cells. |
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Cell. Immunol. |
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Dietary conjugated linoleic acid increases the mRNA ratio of Bax/Bcl-2 in the colonic mucosa of rats. |
2004 |
J. Nutr. Biochem. |
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Inhibition of inflammation contributes to organ protection of atenolol in sinoaortic-denervated rats. |
2004 |
J. Cardiovasc. Pharmacol. |
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Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils. |
2004 |
Metab. Clin. Exp. |
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Granulocyte colony-stimulating factor (filgrastim) treatment primes for increased ex vivo inducible prostanoid release. |
2004 |
J. Pharmacol. Exp. Ther. |
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Determinants of platelet activation in human essential hypertension. |
2004 |
Hypertension |
pmid:14656953
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Anti-inflammatory effects of a traditional Korean herbal formulation, Silsosangami, consisting of seven medicinal herbs: effect on hemolysis, neutrophil function, and gene expressions of iNOS and COX-2. |
2004 |
Vascul. Pharmacol. |
pmid:15664882
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Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders. |
2004 |
Acta Obstet Gynecol Scand |
pmid:15548142
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Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. |
2004 |
Circulation |
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[Effects of the extracts from decoction for resuscitation and its component herbs on PGI2, TXA2 and NO release from rat vascular endothelial cells under hypoxia in vitro]. |
2004 |
Zhongguo Zhong Yao Za Zhi |
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[Changes of the platelet function and serum anticardiolipin antibody in patients with pulmonary thromboembolism]. |
2004 |
Zhonghua Jie He He Hu Xi Za Zhi |
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[The effects of lupus anticoagulant on pulmonary thromboembolism]. |
2004 |
Zhonghua Jie He He Hu Xi Za Zhi |
pmid:15634384
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Franz KB |
A functional biological marker is needed for diagnosing magnesium deficiency. |
2004 |
J Am Coll Nutr |
pmid:15637224
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Ganafa AA et al. |
Amlodipine attenuates oxidative stress-induced hypertension. |
2004 |
Am. J. Hypertens. |
pmid:15363814
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Circulating levels of cyclooxygenase metabolites in experimental Trypanosoma cruzi infections. |
2004 |
Mediators Inflamm. |
pmid:15545053
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Wu JX et al. |
Changes in somatostatin receptor expression of the pancreas and effectiveness of octreotide in rats with acute necrotizing pancreatitis. |
2004 |
Chin J Dig Dis |
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Argan (Argania spinosa) oil lowers blood pressure and improves endothelial dysfunction in spontaneously hypertensive rats. |
2004 |
Br. J. Nutr. |
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Phenylpropanoid glycosides from Scrophularia scorodonia: in vitro anti-inflammatory activity. |
2004 |
Life Sci. |
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Proinflammatory cytokines enhance COX-1 gene expression in cultured rat glomerular mesangial cells. |
2004 |
Int. Immunopharmacol. |
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Protective effect of pentoxifylline on volume-induced lung injury in newborn piglets. |
2004 |
Biol. Neonate |
pmid:14981352
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Ikonomidis I et al. |
Reduction of daily life ischaemia by aspirin in patients with angina: underlying link between thromboxane A2 and macrophage colony stimulating factor. |
2004 |
Heart |
pmid:15020512
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What is the lowest dose of aspirin for maximum suppression of in vivo thromboxane production after a transient ischemic attack or ischemic stroke? |
2004 |
Cerebrovasc. Dis. |
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Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation. |
2004 |
Eur. J. Pharmacol. |
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Carrageenan-induced paw edema in rat elicits a predominant prostaglandin E2 (PGE2) response in the central nervous system associated with the induction of microsomal PGE2 synthase-1. |
2004 |
J. Biol. Chem. |
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Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status. |
2004 |
Diabetes |
pmid:15047620
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Uncontrolled hypertension, uncompensated type II diabetes, and smoking have different patterns of vascular dysfunction. |
2004 |
Chest |
pmid:15006938
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Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes. |
2004 |
Blood |
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Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: possible involvement of PGE2. |
2004 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Inhibitory effect of GBH on platelet aggregation through inhibition of intracellular Ca2+ mobilization in activated human platelets. |
2004 |
Life Sci. |
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[Characteristic changes of vascular tension factors in diabetic arterial occlusion of lower extremities]. |
2004 |
Zhongguo Zhong Xi Yi Jie He Za Zhi |
pmid:15495823
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Cyclooxygenase inhibition is associated with downregulation of apolipoprotein AI promoter activity in cultured hepatoma cell line HepG2. |
2004 |
Metab. Clin. Exp. |
pmid:14767868
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TP receptors regulate renal hemodynamics during angiotensin II slow pressor response. |
2004 |
Am. J. Physiol. Renal Physiol. |
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Peck OM et al. |
Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: role of interferon-gamma. |
2004 |
Shock |
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