Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Abortion, Habitual D000026 5 associated lipids
Acidosis D000138 13 associated lipids
Adenocarcinoma D000230 166 associated lipids
Agranulocytosis D000380 7 associated lipids
Airway Obstruction D000402 13 associated lipids
Albuminuria D000419 18 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Anaphylaxis D000707 35 associated lipids
Anemia D000740 21 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina Pectoris, Variant D000788 3 associated lipids
Angina, Unstable D000789 14 associated lipids
Hypoxia D000860 23 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Aortic Arch Syndromes D001015 2 associated lipids
Aortic Rupture D001019 3 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Arteriosclerosis D001161 86 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Weir MR et al. Acute effects of intravenous cyclosporine on blood pressure, renal hemodynamics, and urine prostaglandin production of healthy humans. 1990 Transplantation pmid:2301025
Fan TP et al. Mechanism of action of cyclosporine in preventing cardiac allograft rejection. II. Graft tissue levels of prostacyclin and thromboxane. 1987 Transplantation pmid:3547787
Kawaguchi A et al. Urinary thromboxane excretion in cardiac allograft rejection in immunosuppressed rats. 1987 Transplantation pmid:3547788
Capitanio A et al. Detection of circulating released platelets after renal transplantation. 1982 Transplantation pmid:6461116
Garvin PJ et al. Evaluation of the thromboxane A2 synthetase inhibitor OKY-046 in a warm ischemia-reperfusion rat model. 1996 Transplantation pmid:8633364
Markewitz A et al. Reduction of cyclosporine-induced nephrotoxicity by cilastatin following clinical heart transplantation. 1994 Transplantation pmid:8154033
Kim YI et al. Hepatoprotection by a PGI2 analogue in complete warm ischemia of the pig liver. Prostanoid release from the reperfused liver. 1994 Transplantation pmid:7940729
Khirabadi BS et al. Urine immunoreactive thromboxane B2 in rat cardiac allograft rejection. 1985 Transplantation pmid:3880966
Textor SC et al. Systemic and renal hemodynamic differences between FK506 and cyclosporine in liver transplant recipients. 1993 Transplantation pmid:7685934
Petric R et al. Amelioration of experimental cyclosporine nephrotoxicity by calcium channel inhibition. 1992 Transplantation pmid:1465778
Johnson BF et al. Urinary thromboxane and 6-keto-prostaglandin F1 alpha are early markers of acute rejection in experimental pancreas transplantation. 1994 Transplantation pmid:7518618
Youngelman DF et al. Effects of chronic cyclosporine administration on renal blood flow and intrarenal blood flow distribution. 1991 Transplantation pmid:1994546
Elzinga L et al. Modification of experimental nephrotoxicity with fish oil as the vehicle for cyclosporine. 1987 Transplantation pmid:3810835
Coffman TM et al. Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity. 1987 Transplantation pmid:3810836
García-Valdecasas JC et al. Prostacyclin, thromboxane, and oxygen free radicals and postoperative liver function in human liver transplantation. 1995 Transplantation pmid:7570973
Moore TC et al. Depression of peripheral lymph node lymphocyte traffic in sheep following central venous allogeneic whole-blood transfusion. 1990 Transplantation pmid:1970202
Suckfüll MM et al. The contribution of endothelial cells to hyperacute rejection in xenogeneic perfused working hearts. 1994 Transplantation pmid:8310518
Post S et al. Prostanoid release in experimental liver transplantation. 1990 Transplantation pmid:2316009
Ruiz P et al. Evidence that pretransplant donor blood transfusion prevents rat renal allograft dysfunction but not the in situ cellular alloimmune or morphologic manifestations of rejection. 1988 Transplantation pmid:3276038
Kawaguchi A et al. Increase in urinary thromboxane B2 in rats caused by cyclosporine. 1985 Transplantation pmid:4024243