Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mitchell MD et al. | Thromboxane B2 in amniotic fluid before and during labour. | 1978 | Br J Obstet Gynaecol | pmid:656348 |
| Raz A et al. | Biosynthesis of thromboxane B2 and 12-L-hydroxy-5,8,10-heptadecatrienoic acid in human platelets. Evidence for a common enzymatic pathway. | 1978 | Eur. J. Biochem. | pmid:658053 |
| McMillan RM et al. | Malonaldehyde formation in intact platelets is catalysed by thromboxane synthase. | 1978 | Biochem. J. | pmid:743261 |
| Chignard M et al. | Synthesis of thromboxane B2 in incubates of dog platelet-rich plasma with arachidonic acid and its inhibition by different drugs. | 1978 | Biochem. Biophys. Res. Commun. | pmid:743319 |
| Adcock JJ et al. | The mechanism of enhancement by fatty acid hydroperoxides of anaphylactic mediator release. | 1978 | Prostaglandins | pmid:81495 |
| Boura AL and Murphy RD | Thromboxane B2 inhibits prostaglandin E2 inactivation by the rat isolated perfused lung. | 1978 Jul-Aug | Clin. Exp. Pharmacol. Physiol. | pmid:699382 |
| Mitchell MD et al. | Thromboxane B-2 in the plasma and amniotic fluid of late pregnant and periparturient sheep. | 1979 | J. Reprod. Fertil. | pmid:423152 |
| Folkert VW and Schlondorff D | Prostaglandin synthesis in isolated glomeruli. | 1979 | Prostaglandins | pmid:441427 |
| Parker CW et al. | Formation of thromboxane B2 and hydroxyarachidonic acids in purified human lymphocytes in the presence and absence of PHA. | 1979 | J. Immunol. | pmid:448099 |
| Needleman P et al. | Platelet and blood vessel arachidonate metabolism and interactions. | 1979 | J. Clin. Invest. | pmid:372240 |
| Morley J et al. | Prostaglandin and thromboxane production by human and guinea-pig macrophages and leucocytes. | 1979 | Prostaglandins | pmid:493559 |
| Meyers KM et al. | A dominant role of thromboxane formation in secondary aggregation of platelets. | 1979 | Nature | pmid:503210 |
| de Deckere EA et al. | Influence of type of dietary fat on the prostaglandin release from isolated rabbit and rat hearts and from rat aortas. | 1979 | Prostaglandins | pmid:504696 |
| Powell WS | Metabolism of prostaglandins, prostaglandin analogs and thromboxane B2 by lung and liver microsomes from pregnant rabbits. | 1979 | Biochim. Biophys. Acta | pmid:518891 |
| Spagnuolo C et al. | Differential effects of probenecid on the levels of endogenous PGF2 alpha and TXB2 in brain cortex. | 1979 | Prostaglandins | pmid:523683 |
| Bennett A and Sanger GJ | Trimethoquinol selectively antagonises longitudinal muscle contractions of rat isolated gastric fundus to thromboxane B2 and epoxymethano analogues of PGH2 [proceedings]. | 1979 | Br. J. Pharmacol. | pmid:526738 |
| Prancan AV et al. | L8027 and 1-nonyl-imidazole as non-selective inhibitors of thromboxane synthesis. | 1979 | Eur. J. Pharmacol. | pmid:527664 |
| Makheja AN et al. | Effects of onion (Allium cepa) extract on platelet aggregation and thromboxane synthesis. | 1979 | Prostaglandins Med | pmid:552092 |
| Lefer AM et al. | Protective effects of a novel thromboxane analog in lethal traumatic shock. | 1979 | Prostaglandins Med | pmid:552102 |
| Daniel EE et al. | Prostaglandins and myogenic control of tension in lower esophageal sphincter in vitro. | 1979 | Prostaglandins | pmid:379920 |
| Kanzaki Y et al. | Thromboxane as possible trigger of liver regeneration. | 1979 | Cell Mol Biol Incl Cyto Enzymol | pmid:535003 |
| Lewy RI et al. | Comparison of plasma concentrations of thromboxane B2 in Prinzmetal's variant angina and classical angina pectoris. | 1979 | Clin Cardiol | pmid:544110 |
| Russell FA and Deykin D | The use of high pressure liquid chromatography (HPLC) for the separation of radiolabeled arachidonic acid and its metabolities produced by thrombin-treated human platelets. I. The validation of the technique. | 1979 | Prostaglandins | pmid:523671 |
| Roberts LJ et al. | Prostaglandin thromboxane, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid production by ionophore-stimulated rat serosal mast cells. | 1979 | Biochim. Biophys. Acta | pmid:389290 |
| Dutilh CE et al. | Study of the two pathways for arachidonate oxygenation in blood platelets. | 1979 | Lipids | pmid:34075 |
| Kelly JP et al. | Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. | 1979 | J. Immunol. | pmid:109510 |
| Whittle BJ | Prostaglandin synthetase inhibitors. Drugs which affect arachidonic acid metabolism. | 1979 | Acta Obstet Gynecol Scand Suppl | pmid:111464 |
| Robinson JS et al. | Prostaglandin E, thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid and maternal plasma of rhesus monkeys (Macaca mulatta) during the latter third of gestation. | 1979 | J. Endocrinol. | pmid:112214 |
| Burch RM et al. | Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of imidazole. | 1979 | J. Pharmacol. Exp. Ther. | pmid:113526 |
| Patrono C et al. | Inhibition of platelet cyclooxygenase by aspirin-like drugs: methods for in vitro and ex vivo assessment. | 1979 | Agents Actions Suppl. | pmid:115255 |
| Wong PY and Cheung WY | Calmodulin stimulates human platelet phospholipase A2. | 1979 | Biochem. Biophys. Res. Commun. | pmid:116656 |
| Okuma M and Uchino H | Altered arachidonate metabolism by platelets in patients with myeloproliferative disorders. | 1979 | Blood | pmid:116695 |
| Best LC et al. | Evidence that extracellular calcium ions inhibit thromboxane B2 biosynthesis by human platelets. | 1979 | Biochem. Biophys. Res. Commun. | pmid:117802 |
| Oelz O | [The arachidonic acid metabolites (prostaglandins, thromboxanes, prostacyclin, leucotrienes):basics and clinical implications (author's transl)]. | 1979 | Ther Umsch | pmid:119331 |
| Robak J and Kasperczyk H | [Prostaglandin synthetase components (author's transl)]. | 1979 | Postepy Biochem. | pmid:120943 |
| Tremoli E et al. | Platelet thromboxanes and serum-cholesterol. | 1979 | Lancet | pmid:84115 |
| Makheia AN et al. | Inhibition of platelet aggregation and thromboxane synthesis by onion and garlic. | 1979 | Lancet | pmid:86023 |
| Lewy RI et al. | Intravenous heparin initiates in-vivo synthesis and release of thromboxane in angina pectoris. | 1979 | Lancet | pmid:87990 |
| Güllner HG et al. | Prostacyclin overproduction in Bartter's syndrome. | 1979 | Lancet | pmid:90861 |
| Davis TM et al. | Prostacyclin and thromboxane metabolites in diabetes. | 1979 | Lancet | pmid:90875 |
| Ford-Hutchinson AW et al. | The aggregation of rat neutrophils by arachidonic acid: a possible bioassay for lipoxygenase activity. | 1979 | J. Pharm. Pharmacol. | pmid:43380 |
| Gorman RR et al. | Independence of the cyclic AMP-lowering activity of thromboxane A2 from the platelet release reaction. | 1979 | Biochim. Biophys. Acta | pmid:216409 |
| Dembińska-Kièć A et al. | Prostacyclin-dependent differences in TXA2 formation by platelets from normal and atherosclerotic rabbits. | 1979 | Atherosclerosis | pmid:224890 |
| Fitzpatrick FA and Gorman RR | Regulatory role of cyclic adenosine 3',5'-monophosphate on the platelet cyclooxygenase and platelet function. | 1979 | Biochim. Biophys. Acta | pmid:216415 |
| Best LC et al. | Mode of action of dipyridamole on human platelets. | 1979 | Thromb. Res. | pmid:229583 |
| Marcus AJ | The role of prostaglandins in platelet function. | 1979 | Prog Hematol | pmid:230534 |
| Spagnuolo C et al. | PGF2 alpha, thromboxane B2 and HETE levels in gerbil brain cortex after ligation of common carotid arteries and decapitation. | 1979 | Prostaglandins | pmid:230539 |
| Jonsson CE et al. | Efflux of cyclic AMP, prostaglandin E2 and F2 alpha and thromboxane B2 in leg lymph of rabbits after scalding injury. | 1979 | Acta Physiol. Scand. | pmid:232367 |
| Karmazyn M and Dhalla NS | Thromboxane B2: a cardiodepressant of isolated rat hearts and inhibitor of sarcolemma Na+ - K+ stimulated ATPase activity. | 1979 | Prostaglandins Med | pmid:233217 |
| Kass MA and Holmberg NJ | Prostaglandin and thromboxane synthesis by microsomes of rabbit ocular tissues. | 1979 | Invest. Ophthalmol. Vis. Sci. | pmid:761971 |