Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pain D010146 64 associated lipids
Contusions D003288 3 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Pleurisy D010998 20 associated lipids
Burns D002056 34 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Kowalska MA et al. Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets. 2000 Blood pmid:10891429
Bailey SR et al. Differential activation of platelets from normal and allergic ponies by PAF and ADP. 2000 Inflamm. Res. pmid:10893045
Rao AR and Prabhakar MC Screening methods for antiasthmatic agents. 2000 Methods Find Exp Clin Pharmacol pmid:10893704
Cayatte AJ et al. The thromboxane receptor antagonist S18886 but not aspirin inhibits atherogenesis in apo E-deficient mice: evidence that eicosanoids other than thromboxane contribute to atherosclerosis. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10894809
Sugimoto KI et al. Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats. 2000 Clin. Exp. Pharmacol. Physiol. pmid:10901388
Köfeler HC et al. Effect of cytochrome P-450 inhibitors econazole, bifonazole and clotrimazole on prostanoid formation. 2000 Br. J. Pharmacol. pmid:10903961
Toft G et al. Intravenously and topically applied magnesium in the prevention of arterial thrombosis. 2000 Thromb. Res. pmid:10904104
Giedrojć J et al. [Investigation of prostaglandins in supernatant of cultured monocytes]. 2000 Prz. Lek. pmid:10907365
Momi S et al. Involvement of platelets in experimental mouse trypanosomiasis: evidence of mouse platelet cytotoxicity against Trypanosoma equiperdum. 2000 Exp. Parasitol. pmid:10910715
Ogura Y et al. Chemoprevention of biliary carcinogenesis in syrian hamsters by the novel carboxamide derivative IS-741 after initiation with N-nitrosobis(2-oxopropyl)amine (BOP). 2000 Carcinogenesis pmid:10910946
MalatyalioÄŸlu E et al. Levels of stable metabolites of prostacyclin and thromboxane A2 and their ratio in normotensive and preeclamptic pregnant women during the antepartum and postpartum periods. 2000 May-Jun J Matern Fetal Med pmid:10914626
Patrignani P et al. Effects of vitamin E supplementation on F(2)-isoprostane and thromboxane biosynthesis in healthy cigarette smokers. 2000 Circulation pmid:10920066
Dschietzig T et al. Stimulation of pulmonary big endothelin-1 and endothelin-1 by antithrombin III: a rationale for combined application of antithrombin III and endothelin antagonists in sepsis-related acute respiratory distress syndrome? 2000 Crit. Care Med. pmid:10921577
Muscará MN et al. Antihypertensive properties of a nitric oxide-releasing naproxen derivative in two-kidney, one-clip rats. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10924050
Wang JS et al. Effect of strenuous arm exercise on oxidized-LDL-potentiated platelet activation in individuals with spinal cord injury. 2000 Thromb. Haemost. pmid:10928481
Kamata K et al. Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats. 2000 Naunyn Schmiedebergs Arch. Pharmacol. pmid:10935533
Kim WG et al. Vasoconstrictive eicosanoid responses to extracorporeal circulation with or without an oxygenator in fetal lambs. 2000 Int J Artif Organs pmid:10941636
Tsikas D et al. Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. 2000 J Chromatogr A pmid:10941682
Porta C et al. Amifostine, a reactive oxigen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF. 2000 Haematologica pmid:10942928
Sane S et al. Eicosapentaenoic acid reduces pulmonary edema in endotoxemic rats. 2000 J. Surg. Res. pmid:10945939
Krysztopik RJ et al. Lazaroid and pentoxifylline suppress sepsis-induced increases in renal vascular resistance via altered arachidonic acid metabolism. 2000 J. Surg. Res. pmid:10945946
Stanke-Labesque F et al. Angiotensin II-induced contractions in human internal mammary artery: effects of cyclooxygenase and lipoxygenase inhibition. 2000 Cardiovasc. Res. pmid:10946074
Thorwest M et al. Dietary fish oil reduces microvascular thrombosis in a porcine experimental model. 2000 Thromb. Res. pmid:10946095
McCann ME et al. Effect of intravenous infusion of omega-3 and omega-6 lipid emulsions on equine monocyte fatty acid composition and inflammatory mediator production in vitro. 2000 Shock pmid:10947170
Kelly JP et al. Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway. 1979 J. Immunol. pmid:109510
Belton O et al. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. 2000 Circulation pmid:10952950
Siler-Khodr TM et al. Effect of ethanol on thromboxane and prostacyclin production in the human placenta. 2000 Alcohol pmid:10963940
Arakida Y et al. Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs. 2000 Eur. J. Pharmacol. pmid:10969159
Ohata T et al. Role of nitric oxide in a temperature dependent regulation of systemic vascular resistance in cardiopulmonary bypass. 2000 Eur J Cardiothorac Surg pmid:10973545
Togna GI et al. Cisplatin triggers platelet activation. 2000 Thromb. Res. pmid:10973681
Yuk DY et al. Antithrombotic and antiplatelet activities of 2-chloro-3-[4-(ethylcarboxy)-phenyl]-amino-1,4-naphthoquinone (NQ12), a newly synthesized 1,4-naphthoquinone derivative. 2000 Biochem. Pharmacol. pmid:10974210
Sabha M et al. Transdermal nicotine mimics the smoking-induced endothelial dysfunction. 2000 Clin. Pharmacol. Ther. pmid:10976548
van Haeringen NJ et al. Flurbiprofen and enantiomers in ophthalmic solution tested as inhibitors of prostanoid synthesis in human blood. 2000 J Ocul Pharmacol Ther pmid:10977130
Matz RL et al. Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids. 2000 Br. J. Pharmacol. pmid:10991924
Boatman RJ et al. Covalent protein adducts of hydroquinone in tissues from rats: quantitation of sulfhydryl-bound forms following single gavage or intraperitoneal administration or repetitive gavage administration. 2000 Chem. Res. Toxicol. pmid:10995259
WÅ‚odarczyk Z et al. Effects of pentoxifylline treatment on delayed graft function in cadaveric kidney recipients. 2000 Transplant. Proc. pmid:10995988
de Jong CL et al. Maternal thromboxane and prostacyclin levels in relation to fetal birth weight. 2000 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:11000507
Tanaka H et al. Effects of milrinone on platelet aggregation in swine with pulmonary hypertension. 2000 J Crit Care pmid:11011824
Coppola A et al. Homocysteine, coagulation, platelet function, and thrombosis. 2000 Semin. Thromb. Hemost. pmid:11011842
Kim WG et al. Is avoidance of air contact necessary for the in vitro evaluation of thrombogenicity in mechanical circulatory assist devices? 2000 Artif Organs pmid:11012543
Jacoby RF et al. The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. 2000 Cancer Res. pmid:11016626
Van Hecken A et al. Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers. 2000 J Clin Pharmacol pmid:11028250
Ciabattoni G et al. In vivo lipid peroxidation and platelet activation in cystic fibrosis. 2000 Am. J. Respir. Crit. Care Med. pmid:11029317
Boyle JR et al. Endovascular AAA repair attenuates the inflammatory and renal responses associated with conventional surgery. 2000 J. Endovasc. Ther. pmid:11032254
Filipov NM et al. Anti-inflammatory effects of ergotamine in steers. 2000 Proc. Soc. Exp. Biol. Med. pmid:11044256
Parker CR et al. Umbilical cord serum levels of thromboxane B2 in term infants of women who participated in a placebo-controlled trial of low-dose aspirin. 2000 Jul-Aug J Matern Fetal Med pmid:11048830
Delemarre FM et al. Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11049696
Thomson M et al. Thromboxane-B(2) levels in serum of rabbits receiving a single intravenous dose of aqueous extract of garlic and onion. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11049697
Qu X et al. Selenium deficiency-induced alterations in the vascular system of the rat. 2000 Biol Trace Elem Res pmid:11051602
Rahman K and Billington D Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans. 2000 J. Nutr. pmid:11053504