Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen CY et al. | Functional analysis of human thromboxane synthase polymorphic variants. | 2012 | Pharmacogenet. Genomics | pmid:22735388 |
| Shoeb M and Ramana KV | Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages. | 2012 | Free Radic. Biol. Med. | pmid:22067901 |
| Pelligand L et al. | Pharmacokinetic/pharmacodynamic modelling of robenacoxib in a feline tissue cage model of inflammation. | 2012 | J. Vet. Pharmacol. Ther. | pmid:21767277 |
| Wenzel F et al. | Determination of thromboxane formation, soluble CD40L release and thrombopoietin clearance in apheresis platelet concentrates. | 2012 | Platelets | pmid:21806498 |
| Tong Z et al. | Influence of ShuJinHuoXue tablets on ischemia reperfusion injury of animals' skeletal muscle. | 2012 | Molecules | pmid:22801363 |
| Cesari M et al. | Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study. | 2012 | J. Gerontol. A Biol. Sci. Med. Sci. | pmid:22389462 |
| Dragani A et al. | Oxidative stress and platelet activation in subjects with moderate hyperhomocysteinaemia due to MTHFR 677 C→T polymorphism. | 2012 | Thromb. Haemost. | pmid:22782530 |
| Saito Y et al. | Disruption of group IVA cytosolic phospholipase A(2) attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNF-α-mediated pathway. | 2012 | Am. J. Physiol. Heart Circ. Physiol. | pmid:22427514 |
| Mo J et al. | Expression of interleukin-18 in a rat model of deep vein thrombosis. | 2012 | J Cardiovasc Surg (Torino) | pmid:22318348 |
| Hartanto MD et al. | Urinary 11-dehydro-thromboxane Bâ‚‚ and 2,3-dinor-6-keto-prostaglandin-Fâ‚α in healthy post-menopausal and pre-menopausal women receiving aspirin 100 mg. | 2012 | J. Thromb. Thrombolysis | pmid:22311294 |
| Smith JP et al. | Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome. | 2012 | Hypertension | pmid:22311905 |
| Brivio I et al. | The pulmonary pharmacology of [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide] (2NTX-99), an anti-atherotrombotic compound with therapeutic potential in pathological conditions that target lung vasculature. | 2012 | Prostaglandins Other Lipid Mediat. | pmid:22342851 |
| Lemkes BA et al. | The influence of aspirin dose and glycemic control on platelet inhibition in patients with type 2 diabetes mellitus. | 2012 | J. Thromb. Haemost. | pmid:22252020 |
| Matsuzawa S et al. | Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury. | 2012 | Arzneimittelforschung | pmid:22945770 |
| Peters SM et al. | In vivo characterization of inflammatory biomarkers in swine and the impact of flunixin meglumine administration. | 2012 | Vet. Immunol. Immunopathol. | pmid:22648045 |
| Zhou MT et al. | Continuous regional arterial infusion with fluorouracil and octreotide attenuates severe acute pancreatitis in a canine model. | 2012 | PLoS ONE | pmid:22655040 |
| Saadawi S et al. | Inhibitory effects of acetylmelodorinol, chrysin and polycarpol from Mitrella kentii on prostaglandin Eâ‚‚ and Thromboxane Bâ‚‚ production and platelet activating factor receptor binding. | 2012 | Molecules | pmid:22538486 |
| Sadilkova L et al. | The purification step is not crucial in EIA measurements of thromboxane B2 and 11-dehydrothromboxane B2 in human plasma. | 2012 | Clin. Lab. | pmid:22372363 |
| Ju HK et al. | Metabolomic investigation of the anti-platelet aggregation activity of ginsenoside Rkâ‚ reveals attenuated 12-HETE production. | 2012 | J. Proteome Res. | pmid:22873173 |
| Chandrasekaran CV et al. | In vitro comparative evaluation of non-leaves and leaves extracts of Andrographis paniculata on modulation of inflammatory mediators. | 2012 | Antiinflamm Antiallergy Agents Med Chem | pmid:22882083 |