Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hohlfeld T et al. | Variable platelet response to aspirin in patients with ischemic stroke. | 2007 | Cerebrovasc. Dis. | pmid:17519543 |
Allais G et al. | Naproxen sodium in short-term prophylaxis of pure menstrual migraine: pathophysiological and clinical considerations. | 2007 | Neurol. Sci. | pmid:17508177 |
Wong PC et al. | Platelet aggregometry and receptor binding to predict the magnitude of antithrombotic and bleeding time effects of clopidogrel in rabbits. | 2007 | J. Cardiovasc. Pharmacol. | pmid:17513951 |
Hsiao G et al. | Characterization of a novel and potent collagen antagonist, caffeic acid phenethyl ester, in human platelets: in vitro and in vivo studies. | 2007 | Cardiovasc. Res. | pmid:17560560 |
Basselin M et al. | Flurbiprofen, a cyclooxygenase inhibitor, reduces the brain arachidonic acid signal in response to the cholinergic muscarinic agonist, arecoline, in awake rats. | 2007 | Neurochem. Res. | pmid:17562170 |
Aras-Lopéz R et al. | Dexamethasone decreases contraction to electrical field stimulation in mesenteric arteries from spontaneously hypertensive rats through decreases in thromboxane A2 release. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17562850 |
Gurbel PA et al. | Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study. | 2007 | Circulation | pmid:17562955 |
Tu CT et al. | Antifibrotic activity of rofecoxib in vivo is associated with reduced portal hypertension in rats with carbon tetrachloride-induced liver injury. | 2007 | J. Gastroenterol. Hepatol. | pmid:17565644 |
Zheng BH et al. | [The effect of inhaled nitric oxide on endothelium-derived angiokinetic factors in patients with acute high altitude disease]. | 2007 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:17445476 |
Marvin CC et al. | Synthesis of thromboxane B2 via ketalization/ring-closing metathesis. | 2007 | Org. Lett. | pmid:18047355 |
Wang Z et al. | Changes of vasoactive polypeptides during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage. | 2007 | Chin. Med. J. | pmid:18167188 |
DiChiara J et al. | The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study. | 2007 | Diabetes | pmid:17848625 |
Sha JP et al. | [Effect of the recombinant staphylokinase on pancreatic ischemia in severe acute pancreatitis of rats]. | 2007 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:17708840 |
Silvanto M et al. | Effect of 3 g of intravenous paracetamol on post-operative analgesia, platelet function and liver enzymes in patients undergoing tonsillectomy under local anaesthesia. | 2007 | Acta Anaesthesiol Scand | pmid:17711562 |
Shemesh E et al. | Symptoms of posttraumatic stress disorder in patients who have had a myocardial infarction. | 2006 May-Jun | Psychosomatics | pmid:16684940 |
Tuominen OM et al. | Effects of bisphosphonates on prostaglandin E2 and thromboxane B2 production in human whole blood and monocytes stimulated by lipopolysaccharide and A23187. | 2006 Jul-Aug | Methods Find Exp Clin Pharmacol | pmid:16894405 |
Wang LH et al. | Effect of heparin on activation of platelet function in patients during radiofrequency catheter ablation. | 2006 Jan-Feb | Clin. Exp. Pharmacol. Physiol. | pmid:16445701 |
Wynn RL and Cook J | Does ibuprofen block the cardioprotective effects of aspirin in dental patients? | 2006 Jan-Feb | Gen Dent | pmid:16494111 |
Sciulli MG et al. | Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease. | 2006 | Clin. Pharmacol. Ther. | pmid:16890573 |
Shi T et al. | Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V. | 2006 | Arthritis Rheum. | pmid:16868978 |
Ramamurthy S et al. | Characterization of thromboxane A2 receptor signaling in developing rat oligodendrocytes: nuclear receptor localization and stimulation of myelin basic protein expression. | 2006 | J. Neurosci. Res. | pmid:16998891 |
Zhou Y et al. | Increased expression of cyclooxygenase-2 mediates enhanced contraction to endothelin ETA receptor stimulation in endothelial nitric oxide synthase knockout mice. | 2006 | Circ. Res. | pmid:16645140 |
Karkabounas S et al. | Anticarcinogenic and antiplatelet effects of carvacrol. | 2006 | Exp. Oncol. | pmid:16837902 |
Wilder-Smith CH et al. | Dose-effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects. | 2006 | Scand. J. Gastroenterol. | pmid:16497612 |
Brenneis C et al. | Inhibition of prostaglandin E2 synthesis by SC-560 is independent of cyclooxygenase 1 inhibition. | 2006 | FASEB J. | pmid:16816110 |
Baltzer WI et al. | Measurement of urinary 11-dehydro-thromboxane B2 excretion in dogs with gastric dilatation-volvulus. | 2006 | Am. J. Vet. Res. | pmid:16426215 |
Chiu HF et al. | Mechanisms involved in the antiplatelet effect of C-phycocyanin. | 2006 | Br. J. Nutr. | pmid:16469164 |
Rossoni G et al. | Nitric oxide and prostacyclin pathways: an integrated mechanism that limits myocardial infarction progression in anaesthetized rats. | 2006 | Pharmacol. Res. | pmid:16488624 |
Lepäntalo A et al. | Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients. | 2006 | Thromb. Haemost. | pmid:16493486 |
Kurosawa S et al. | Effects of ulinastatin on pulmonary artery pressure during abdominal aortic aneurysmectomy. | 2006 | J Clin Anesth | pmid:16517327 |
Flipo RM | [Are the NSAIDs able to compromising the cardio-preventive efficacy of aspirin?]. | 2006 | Presse Med | pmid:17078596 |
Ibrahim S et al. | Transfer of very low density lipoprotein-associated phospholipids to activated human platelets. | 2006 | J. Lipid Res. | pmid:16293890 |
Cheung PY et al. | Platelet dysfunction in asphyxiated newborn piglets resuscitated with 21% and 100% oxygen. | 2006 | Pediatr. Res. | pmid:16627873 |
Laleman W et al. | A stable model of cirrhotic portal hypertension in the rat: thioacetamide revisited. | 2006 | Eur. J. Clin. Invest. | pmid:16620286 |
Zhao Y et al. | Effect of a Chinese herbal formula, Shi-Bi-Lin, on an experimental model of allergic rhinitis. | 2006 | Ann. Allergy Asthma Immunol. | pmid:16802773 |
Lee KS et al. | Antiplatelet activity of [5-(2-methoxy-5-chlorophenyl)furan-2-ylcarbonyl]guanidine (KR-32570), a novel sodium/hydrogen exchanger-1 and its mechanism of action. | 2006 | Arch. Pharm. Res. | pmid:16756082 |
Peck OM et al. | The phosphatidylinositol 3 kinase pathway regulates tolerance to lipopolysaccharide and priming responses to Staphylococcus aureus and lipopolysaccharide. | 2006 | Shock | pmid:16783195 |
Frelinger AL et al. | Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. | 2006 | Circulation | pmid:16785341 |
Cox D et al. | Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers. | 2006 | Stroke | pmid:16794200 |
Munsterhjelm E et al. | Influence on platelet aggregation of i.v. parecoxib and acetaminophen in healthy volunteers. | 2006 | Br J Anaesth | pmid:16698862 |
Vranic II et al. | Adenosine cardioprotection study in clinical setting of paroxysmal supraventricular tachycardia. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16682179 |
Huntjens DR et al. | Correlation between in vitro and in vivo concentration-effect relationships of naproxen in rats and healthy volunteers. | 2006 | Br. J. Pharmacol. | pmid:16682968 |
Zhang JY et al. | [Study on therapeutic effects of series of muskone on myocardial infarction canines]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:17225541 |
Basili S et al. | Insulin resistance as a determinant of platelet activation in obese women. | 2006 | J. Am. Coll. Cardiol. | pmid:17174194 |
Hrushka NH et al. | [Effect of thromboxane B2 on morphological features of apoptosis in cultured rat hepatocytes exposed to hepatotropic substances]. | 2006 | Fiziol Zh | pmid:17176837 |
Niemi TT et al. | The effect of N-acetylcysteine on blood coagulation and platelet function in patients undergoing open repair of abdominal aortic aneurysm. | 2006 | Blood Coagul. Fibrinolysis | pmid:16607076 |
Chiang N and Serhan CN | New mechanism for an old drug: aspirin triggers anti-inflammatory lipid mediators with gender implications. | 2006 | Compr Ther | pmid:17435267 |
Stergioulas AT and Filippou DK | Effects of physical conditioning on lipids and arachidonic acid metabolites in untrained boys: a longitudinal study. | 2006 | Appl Physiol Nutr Metab | pmid:16900233 |
Chiang N et al. | Aspirin has a gender-dependent impact on antiinflammatory 15-epi-lipoxin A4 formation: a randomized human trial. | 2006 | Arterioscler. Thromb. Vasc. Biol. | pmid:16293793 |
Wolfram RM et al. | Salivary isoprostanes indicate increased oxidation injury in periodontitis with additional tobacco abuse. | 2006 | Biofactors | pmid:17264390 |