Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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van Kooten F et al. | Increased thromboxane biosynthesis is associated with poststroke dementia. | 1999 | Stroke | pmid:10436098 |
Kim HS et al. | Effects of tetrandrine and fangchinoline on human platelet aggregation and thromboxane B2 formation. | 1999 | J Ethnopharmacol | pmid:10433485 |
Mills JL et al. | Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. | 1999 | JAMA | pmid:10432033 |
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McCowan LM et al. | Administration of low-dose aspirin to mothers with small for gestational age fetuses and abnormal umbilical Doppler studies to increase birthweight: a randomised double-blind controlled trial. | 1999 | Br J Obstet Gynaecol | pmid:10428519 |
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Peredo HA et al. | Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10397409 |
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Kubo K et al. | A 21-aminosteroid, U-74006F, attenuates endotoxin-induced lung injury in awake sheep. | 1999 | Respirology | pmid:10382236 |
Cryer B and Feldman M | Effects of very low dose daily, long-term aspirin therapy on gastric, duodenal, and rectal prostaglandin levels and on mucosal injury in healthy humans. | 1999 | Gastroenterology | pmid:10381905 |
Freedman JE et al. | Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene. | 1999 | Circ. Res. | pmid:10381894 |
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Walsh SW et al. | AA-2414, an antioxidant and thromboxane receptor blocker, completely inhibits peroxide-induced vasoconstriction in the human placenta. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10381779 |
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