Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Wang DP et al. | [Effect of the leech on 6-keto-PGF1 alpha, TXB2, total cholesterol and triglycerides in experimental hyperlipemic rabbits]. | 1988 | Zhonghua Nei Ke Za Zhi | pmid:3219953 |
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Wang GQ et al. | [A study of the role of plasma thromboxane B2 and 6-keto-prostaglandin F1 alpha in epidemic hemorrhagic fever]. | 1990 | Zhonghua Nei Ke Za Zhi | pmid:1976492 |
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Dong DC and Zhong L | [Measurement of urinary TXB2, 6-keto-PGF1 alpha by radioimmunoassay and its clinical significance]. | 1987 | Zhonghua Nei Ke Za Zhi | pmid:3451855 |
Shen XY et al. | [Changes in circulatory thromboxane B2 and 6-keto-prostaglandin F1 alpha in acute myocardial infarction]. | 1987 | Zhonghua Nei Ke Za Zhi | pmid:3652838 |
Zhang ZF et al. | [The changes in serum TXB2 and 6-keto-PGF1 alpha in 62 cases with renal disease]. | 1989 | Zhonghua Nei Ke Za Zhi | pmid:2737033 |
Pan YZ et al. | [The clinical significance of platelet activation during exercise-induced myocardial ischemia]. | 1994 | Zhonghua Nei Ke Za Zhi | pmid:7520851 |
Wang M | [Studies on plasma beta-thromboglobulin, thromboxane A2, prostaglandin I2 concentration and platelet count in liver diseases]. | 1992 | Zhonghua Nei Ke Za Zhi | pmid:1395919 |
Mei XW et al. | [The interaction of some active and immunological factors in blood in the development of chronic cor pulmonale]. | 1992 | Zhonghua Nei Ke Za Zhi | pmid:1395928 |
Jin L et al. | [The effect of low dose aspirin on the platelet function in patients with acute myocardial infarction]. | 1993 | Zhonghua Nei Ke Za Zhi | pmid:8269785 |
Wang S | [The effect of captopril on hemodynamics in patients of chronic obstructive pulmonary disease with pulmonary hypertension]. | 1993 | Zhonghua Nei Ke Za Zhi | pmid:8269786 |
Yu HZ | [Determinations of CSF and plasma concentrations of thromboxane B2 and 6-keto-PGF1 alpha in stroke patients]. | 1988 | Zhonghua Shen Jing Jing Shen Ke Za Zhi | pmid:3402273 |
Gao XG | [Plasma concentrations of thromboxane B2 and 6-keto-PGF1 alpha in patients with cerebral hemorrhage]. | 1988 | Zhonghua Shen Jing Jing Shen Ke Za Zhi | pmid:3402274 |
Jiang K | [The study of occurrence mechanism in acute and chronic cerebral vasospasm]. | 1992 | Zhonghua Shen Jing Jing Shen Ke Za Zhi | pmid:1304997 |
Cao QL | [Dynamic analysis of plasma TXB2 determined by radioimmunoassay in 30 cases of cerebral infarction]. | 1986 | Zhonghua Shen Jing Jing Shen Ke Za Zhi | pmid:3743234 |
Xie P | [Clinical significance of TXB2 level in CSF of patients with acute cerebrovascular diseases]. | 1986 | Zhonghua Shen Jing Jing Shen Ke Za Zhi | pmid:3743244 |
Zhao J | [Treatment of acute cerebral infarction with PGI2--evaluating the clinical effect and observation of dynamic changes in plasma TXB2 and 6-keto PGF1 alpha levels]. | 1991 | Zhonghua Shen Jing Jing Shen Ke Za Zhi | pmid:1889319 |
Teng Y | [The effect of hyperbaric oxygenation on prostaglandin I2 and thromboxane A2 during reperfusion for experimental cerebral ischemia in rabbits]. | 1992 | Zhonghua Shen Jing Jing Shen Ke Za Zhi | pmid:1591957 |
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Mao E et al. | [Pancreatic ischemia: a continuous injury factor in acute necrotic pancreatitis]. | 1997 | Zhonghua Wai Ke Za Zhi | pmid:10374521 |
Xing X et al. | [Preserving remnant liver function after major hepatic vein occlusion]. | 1998 | Zhonghua Wai Ke Za Zhi | pmid:11825430 |
Tian L | [Changes in platelet aggregation, TXB2 and 6-keto-PGF1 alpha in surgical shock]. | 1990 | Zhonghua Wai Ke Za Zhi | pmid:2096057 |
Xing X and Xia S | [The injury of liver sinusoidal endothelial cells in a rat's isolated liver perfusion (ILP) model for regional chemotherapy]. | 1996 | Zhonghua Wai Ke Za Zhi | pmid:9275689 |
Xiao J et al. | [Effects of platelet activating factor and platelet activating factor receptor antagonist on spinal cord blood flow after spinal cord injury]. | 1995 | Zhonghua Wai Ke Za Zhi | pmid:8762548 |
Miao XY | [Plasma level and effects of thromboxane A2 and 6-keto-PGF1 alpha in patients with acute obstructive suppurative cholangitis]. | 1990 | Zhonghua Wai Ke Za Zhi | pmid:2379443 |
Wang ZG et al. | [Experimental study and clinical application of endothelium seeded vena caval prostheses]. | 1994 | Zhonghua Wai Ke Za Zhi | pmid:7842898 |
Zhang L | [Effect of pollen typhae on 6-keto-PGF1 alpha, TXB2, TC and HDL-C in chronic hyperlipemic rabbits]. | 1986 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:3582146 |
Cai W | [Changes in plasma TXB2 and 6-keto-PGF1 alpha and left atrial thrombosis in mitral stenosis]. | 1990 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:2209410 |
Wang H | [Effects of corn pollen on the peroxides and 6-keto-PGF1 alpha/TXB2 in hyperlipidemic rabbits]. | 1990 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:2093561 |
Yang Y | [Analysis of serum TXB2 in essential hypertension]. | 1986 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:3743385 |
Xu ZC | [An experimental study on the mechanism of antiatherosclerotic effect of nifedipine]. | 1993 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:8243235 |
Li L | [Effects of svate on platelet morphology and function in patients with coronary heart disease and hypertension]. | 1991 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:1655375 |
Jin L et al. | [Platelet functions in patients with acute myocardial infarction]. | 1989 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:2636123 |
Chen SL et al. | [Effects of experimental coronary artery stenosis on platelet function]. | 1989 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:2636126 |
Bai XJ | [Plasma TXB2, 6-keto-PGF1 alpha content and their ratio in myocardial infarction patients]. | 1989 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:2637134 |
Luo Y | [Improvement of prostacyclin-thromboxane A2 balance in patients with acute myocardial infarction by intermittent aspirin]. | 1993 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:8194434 |
Gong LS et al. | [Plasma thromboxane B2 and 6-keto-prostaglandin F1-alpha concentrations in patients with essential and renovascular hypertension]. | 1986 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:3755674 |
Wang A and Gu T | [The relation between coronary diseases and lipid peroxidation]. | 1991 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:1914860 |
Wang L | [Effect of captopril on urinary 6-keto-PGF1 alpha, thromboxane B2 in inbred SHR rats]. | 1991 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:1821358 |
Wu YZ | [Changes in plasma TxB2 and 6-keto-PGF1 alpha in patients with retinal vein occlusion]. | 1993 | Zhonghua Yan Ke Za Zhi | pmid:8020381 |
Song LY | [Experimental study of the pathological mechanism of thromboxane A2 in alkaline ocular burn]. | 1990 | Zhonghua Yan Ke Za Zhi | pmid:2086144 |
Wang BZ et al. | [Association of the Pro1770Leu polymorphism in CYP5A1 gene with myocardial infarction in Uigur population of Xinjiang]. | 2010 | Zhonghua Yi Xue Yi Chuan Xue Za Zhi | pmid:20931532 |
Chen LB et al. | [Coagulation and prothrombotic state parameters: clinical analysis in early pregnancy]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24284247 |
Chen SY | [Correlation of platelet aggregation, platelet cAMP content and TXB2 synthesis in patients with diabetes mellitus]. | 1988 | Zhonghua Yi Xue Za Zhi | pmid:2853988 |
Liu J | [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. | 1983 | Zhonghua Yi Xue Za Zhi | pmid:6418338 |
Cai D et al. | [Changes in cytosolic free calcium and thromboxane B2 synthesis in platelets from diabetic subjects]. | 1995 | Zhonghua Yi Xue Za Zhi | pmid:7584570 |
Deng XF | [Effect of indomethacin on septic shock experimental and preliminary clinical trials]. | 1988 | Zhonghua Yi Xue Za Zhi | pmid:3228741 |