Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jacoby RF et al. | The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. | 2000 | Cancer Res. | pmid:11016626 |
| Van Hecken A et al. | Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers. | 2000 | J Clin Pharmacol | pmid:11028250 |
| Ciabattoni G et al. | In vivo lipid peroxidation and platelet activation in cystic fibrosis. | 2000 | Am. J. Respir. Crit. Care Med. | pmid:11029317 |
| Boyle JR et al. | Endovascular AAA repair attenuates the inflammatory and renal responses associated with conventional surgery. | 2000 | J. Endovasc. Ther. | pmid:11032254 |
| Filipov NM et al. | Anti-inflammatory effects of ergotamine in steers. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:11044256 |
| Parker CR et al. | Umbilical cord serum levels of thromboxane B2 in term infants of women who participated in a placebo-controlled trial of low-dose aspirin. | 2000 Jul-Aug | J Matern Fetal Med | pmid:11048830 |
| Delemarre FM et al. | Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11049696 |
| Thomson M et al. | Thromboxane-B(2) levels in serum of rabbits receiving a single intravenous dose of aqueous extract of garlic and onion. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11049697 |
| Qu X et al. | Selenium deficiency-induced alterations in the vascular system of the rat. | 2000 | Biol Trace Elem Res | pmid:11051602 |
| Rahman K and Billington D | Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans. | 2000 | J. Nutr. | pmid:11053504 |
| De Somer F et al. | Phosphorylcholine coating of extracorporeal circuits provides natural protection against blood activation by the material surface. | 2000 | Eur J Cardiothorac Surg | pmid:11053824 |
| Suzuki N et al. | Difference in urinary LTE4 and 11-dehydro-TXB2 excretion in asthmatic patients. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:11060902 |
| Ferry DR et al. | A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints. | 2000 | Ann. Oncol. | pmid:11061613 |
| Kawasaki K et al. | Inhibition of 12(S)-hydroxyeicosatetraenoic acid (12-HETE) production suppressed the intimal hyperplasia caused by poor-runoff conditions in the rabbit autologous vein grafts. | 2000 | J. Cardiovasc. Pharmacol. | pmid:11065214 |
| Vazquez-Cruz B et al. | Increased renal vasoconstriction and gene expression of cyclooxygenase-1 in renovascular hypertension. | 2000 | J. Cardiovasc. Pharmacol. | pmid:11065217 |
| Naito Y et al. | Increase in blood pressure with enhanced Na+, K+ -ATPase activity in stroke-prone spontaneously hypertensive rats after 4-weeks intake of rapeseed oil as the sole dietary fat. | 2000 | Pharmacol. Toxicol. | pmid:11068856 |
| Praticò D et al. | Endogenous biosynthesis of thromboxane and prostacyclin in 2 distinct murine models of atherosclerosis. | 2000 | Blood | pmid:11090066 |
| Darlametsos IE et al. | Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090252 |
| Cruz MA et al. | Vascular reactivity to angiotensin II and eicosanoid production in the human placenta from term and preterm pregnancy. | 2000 | Gynecol. Obstet. Invest. | pmid:11093047 |
| Basu S et al. | Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. | 2000 | Clin. Sci. | pmid:11099394 |